Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   SSU12_RS05115 Genome accession   NC_017619
Coordinates   1034024..1035403 (-) Length   459 a.a.
NCBI ID   WP_012027074.1    Uniprot ID   -
Organism   Streptococcus suis SS12     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1029024..1040403
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSU12_RS05085 (SSU12_1002) - 1029469..1030059 (-) 591 WP_012027067.1 class I SAM-dependent methyltransferase -
  SSU12_RS05090 (SSU12_1003) coaA 1030168..1031088 (+) 921 WP_012027068.1 type I pantothenate kinase -
  SSU12_RS05095 (SSU12_1004) rpsT 1031147..1031395 (+) 249 WP_012027069.1 30S ribosomal protein S20 -
  SSU12_RS05100 (SSU12_1005) tnpA 1031537..1032051 (-) 515 Protein_954 IS200/IS605 family transposase -
  SSU12_RS05105 (SSU12_1006) - 1032464..1033693 (-) 1230 WP_012027071.1 transglutaminase domain-containing protein -
  SSU12_RS05115 (SSU12_1008) ciaH 1034024..1035403 (-) 1380 WP_012027074.1 cell wall metabolism sensor histidine kinase WalK Regulator
  SSU12_RS05120 (SSU12_1009) ciaR 1035396..1036067 (-) 672 WP_009909965.1 response regulator transcription factor Regulator
  SSU12_RS05125 (SSU12_1010) - 1036261..1036641 (-) 381 WP_012027076.1 hypothetical protein -
  SSU12_RS05130 (SSU12_1011) - 1037026..1038230 (+) 1205 Protein_959 IS110 family transposase -
  SSU12_RS05135 (SSU12_1012) phoU 1038432..1039088 (-) 657 WP_012028219.1 phosphate signaling complex protein PhoU -
  SSU12_RS05140 (SSU12_1013) pstB 1039117..1039875 (-) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51955.61 Da        Isoelectric Point: 5.5984

>NTDB_id=49684 SSU12_RS05115 WP_012027074.1 1034024..1035403(-) (ciaH) [Streptococcus suis SS12]
MPKRIGKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKEEPAMAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKEQKNTRDGDQLRLGVNTHVLLYSKSGEMVNPDTFTGLANLPLDKEKLGEIKETTVESSFGM
SEDYRYITIGLATDELGYYSSYDIKYATILVNVSQIKSSIESYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPETTILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGTIQIAANIKDKLVCFTVIDNGLGISDV
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKNLDGEISVRDNQPKGTIFEVRLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=49684 SSU12_RS05115 WP_012027074.1 1034024..1035403(-) (ciaH) [Streptococcus suis SS12]
ATGCCTAAGCGAATCGGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTATCAAAATTCAGATAATACCTTGAAACGGA
TTAAGGAAGAACCAGCGATGGCTGTTGGTTTTGCGATCGCAAGAACCTATGAGCCCAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAGAACAAAAAAATACTAGAGATGG
AGATCAGCTGAGATTAGGTGTCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCGGATACTTTTA
CTGGTTTGGCCAACCTACCGTTAGATAAGGAAAAATTGGGTGAAATTAAGGAAACTACGGTTGAATCAAGTTTTGGTATG
TCTGAAGATTATCGCTATATAACGATTGGGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTGGTGAATGTCAGCCAAATTAAATCTTCCATTGAGAGCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGTTGATTTCTATACTAGCAAGTATTTACCTATCGAATCTTAGCATGCGTCCAATCCTAATTAGTTATCAAAAACAA
AAAGACTTCGTTGAAAATGCTAGTCATGAGTTACGCACACCGTTGGCAGTTCTTCAAAATCGCCTGGAAAGTCTATTTCG
TCATCCCGAGACAACTATTTTGGAAAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTTCGAAATATGCGACTATTAA
CAACGAACTTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACTCTAACAGTTAATAATTTGATTCATCAGCCAAT
TCGAACAGACAAGGTTTTGATTAAACAGTTGCTCACCATTTTGTTTGACAACGCTATGAAGTATACCGATGATGATGGGA
CAATTCAAATAGCAGCTAATATCAAGGACAAACTAGTTTGTTTTACAGTTATTGACAATGGTTTGGGAATCAGCGATGTC
GATAAAAAGAAAATCTTTGATCGCTTTTACCGAGTTGACAAGGCTAGAACACGTCAAAAAGGTGGATTTGGTTTAGGTTT
ATCTTTAGCTCAACAAATTATTAAGAATCTAGATGGTGAGATTTCTGTGAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTACGTTTACCCAAATAA

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.237

100

0.492
  ciaH Streptococcus pneumoniae D39

49.237

100

0.492
  ciaH Streptococcus pneumoniae R6

49.237

100

0.492
  ciaH Streptococcus pneumoniae TIGR4

49.237

100

0.492
  ciaH Streptococcus mutans UA159

49.664

97.386

0.484

Multiple sequence alignment