Detailed information NTG0049580

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: SSGZ1_RS03410
• Genome accession: NC_017617
• Coordinates: 686471..688708 (+)
• Length: 745 a.a.
• NCBI ID: WP_012775040.1
• Uniprot ID: -
• Organism: Streptococcus suis GZ1
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 681471..693708

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSGZ1_RS03385 (SSGZ1_0639)	-	681543..682472 (-)	930	WP_012775038.1	ABC transporter substrate-binding protein	-
SSGZ1_RS03390 (SSGZ1_0640)	-	682485..683270 (-)	786	WP_011922762.1	ABC transporter ATP-binding protein	-
SSGZ1_RS03395 (SSGZ1_0642)	-	683422..684866 (-)	1445	Protein_624	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
SSGZ1_RS03400 (SSGZ1_0643)	-	685013..685762 (+)	750	WP_012775039.1	lysophospholipid acyltransferase family protein	-
SSGZ1_RS03405 (SSGZ1_0644)	-	685825..686487 (+)	663	WP_011922190.1	helix-hairpin-helix domain-containing protein	-
SSGZ1_RS03410 (SSGZ1_0645)	comEC/celB	686471..688708 (+)	2238	WP_012775040.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SSGZ1_RS10510 (SSGZ1_0646)	-	688725..688850 (+)	126	Protein_628	IS982 family transposase	-
SSGZ1_RS03420 (SSGZ1_0647)	-	689033..689689 (+)	657	WP_011922763.1	CBS domain-containing protein	-
SSGZ1_RS03425 (SSGZ1_0648)	-	689783..690610 (+)	828	WP_011922194.1	hypothetical protein	-
SSGZ1_RS03430 (SSGZ1_0649)	-	690616..691887 (+)	1272	WP_011922195.1	toxic anion resistance protein	-
SSGZ1_RS03435 (SSGZ1_0650)	-	691924..692790 (-)	867	WP_002935357.1	YitT family protein	-
SSGZ1_RS03440 (SSGZ1_0651)	tmk	692965..693603 (+)	639	WP_012775041.1	dTMP kinase	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 83965.92 Da
• Isoelectric Point: 7.8195

>NTDB_id=49580 SSGZ1_RS03410 WP_012775040.1 686471..688708(+) (comEC/celB) [Streptococcus suis GZ1]
MSRLSKLPCQPVHLAVLAVAAYFAVHSFSLLTMCLLSLVLAVFGVRQGKTVFLKTLPLLTLCGLFFGCQKVQWERAAQSA
PEQVTTVQVIPDTIDINGDSLSFRGRADGQNYQVFYKLTSQEEQTYFQNLADLVQLEVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVKLTAIKKIVPVQSWNVFDWLSTWRRQALVYVKTNFPAPMSHYMTGLLFGELDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKETVDKLQIPFSLVYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFICLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFYAFQPLSILLTFVFSFVFDVLLLPGLSV
IFLLSPVVKMTWVNGFFVFMEKIIVWVADLGLRPWILGKPSELVLLLLLVSLFLLYDFHRRKKWLLGLSLVLALLFFITK
HPLENEVTVLDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIVVSPGSLTVPDFVATLKKINVPVHVVKVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIETYPNLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALVSAGENNRYKHPHQETLERFDSRNIQ
VYRTDQQGAIRFRGWKEWKIETVRR

Nucleotide

• Length: 2238 bp

>NTDB_id=49580 SSGZ1_RS03410 WP_012775040.1 686471..688708(+) (comEC/celB) [Streptococcus suis GZ1]
ATGTCACGGTTGAGTAAGCTCCCCTGCCAGCCCGTTCACCTGGCAGTCTTGGCGGTGGCAGCTTACTTTGCAGTCCACTC
TTTTTCCCTCTTGACAATGTGCCTGCTCAGCTTGGTGTTAGCTGTCTTTGGTGTTCGGCAAGGTAAGACAGTTTTCCTCA
AAACGCTGCCGCTTCTAACCCTGTGTGGTCTCTTTTTCGGATGCCAAAAGGTCCAATGGGAGCGGGCAGCTCAGTCAGCC
CCAGAGCAAGTGACGACTGTGCAGGTCATTCCAGATACCATAGACATCAATGGCGACAGCTTGTCTTTTCGTGGTCGGGC
TGATGGACAAAACTATCAGGTTTTCTACAAATTAACCAGTCAGGAGGAGCAGACCTATTTTCAAAATCTGGCAGACCTGG
TCCAGCTAGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGCGGAATTTCAAGGGCTTTGACTATCAGGCCTATCTG
AAAACACAGGGCATCTATCGGACTGTCAAGCTAACGGCGATTAAGAAGATTGTCCCTGTCCAGTCTTGGAATGTTTTTGA
CTGGCTGTCAACTTGGCGGAGGCAGGCCTTGGTCTATGTCAAAACCAATTTTCCGGCTCCCATGAGTCACTACATGACAG
GGCTTTTGTTTGGGGAGCTGGATAGTGATTTTGACCAGATGAGTGACCTCTATTCCAGTCTAGGAATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTGGGCTTTTTCATCGACAAGTTTCGTTGGATTTTGTTGCGTCTGGGCTTGACCAAGGAAAC
AGTGGATAAGTTACAAATTCCCTTTTCCCTTGTCTATGCTGGTTTGACAGGCTTTTCTGTGTCGGTGGTGCGGTCCTTGG
TCCAAAAAATTCTGGGTAATCTAGGCTTGCGGAAGTTGGATAATTTTGCGGTGACGGTCTTTATCTGTCTGTTGATACTG
CCCCGATTTTTACTGACAGCAGGAGGAGTGCTGACTTTTACTTATGCTTTCTTGCTGACGGTCTTTGATTTTGAGGATTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCACTGGGAATTTTGCCGGTGCTTATGACCTATTTCTATG
CCTTTCAGCCTCTATCTATCCTCTTGACCTTTGTCTTTTCCTTTGTCTTTGATGTCCTACTCTTGCCAGGTTTGTCAGTC
ATTTTTCTCCTGTCGCCAGTTGTCAAGATGACTTGGGTCAACGGATTTTTCGTCTTTATGGAGAAAATCATTGTCTGGGT
GGCTGATTTGGGATTGCGGCCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTCTTGCTTTTGCTGGTCAGCCTCTTCT
TGCTCTACGATTTCCACAGGAGAAAGAAATGGCTTCTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATCACCAAA
CACCCGCTGGAAAATGAGGTGACGGTGCTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTTCTGATTGATGTAGGCGGACGAGTCGATTTCGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGTGTGGATAGGATTGATAGTTTAGTCCTGACCCACACCGACACAGAC
CATGTGGGGGATGTGCTGGAAGTGGCGAAGCAGGTCCAGATTGGTCGGATTGTCGTGTCGCCGGGAAGTCTGACGGTGCC
TGACTTTGTAGCGACCTTGAAAAAAATCAATGTTCCTGTCCATGTGGTAAAAGTGGGCGACCGCCTACCAATTTTTGACT
CCTATCTGGAGGTCCTCTATCCAGACGGGACAGGCGACGGTGGCAATAATGACTCCATTGTCCTTTACGGTCGCTTGTTG
GAAACTAACTTTCTCTTTACAGGAGACCTGGAGCAAGGGGAGTTGGACTTGATAGAAACCTATCCCAACCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCATGGCTCCAAAGGCTCTTCTTATCCTGAATTTTTAGACCATATCGGTGCCAAGATTGCCT
TGGTATCTGCTGGAGAAAACAACCGCTACAAGCATCCTCACCAAGAAACCTTGGAACGATTTGACAGCCGGAATATCCAA
GTCTATCGCACAGACCAGCAAGGAGCCATTCGCTTCCGAGGTTGGAAGGAGTGGAAGATTGAGACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-698)

• Domain of unknown function (DUF4131) (DUF4131) (30-175)

• Competence protein (Competence) (215-461)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	53.774	99.597	0.536
comEC/celB	Streptococcus mitis NCTC 12261	52.782	98.926	0.522
comEC/celB	Streptococcus pneumoniae TIGR4	51.973	98.658	0.513
comEC/celB	Streptococcus pneumoniae Rx1	51.701	98.658	0.51
comEC/celB	Streptococcus pneumoniae D39	51.701	98.658	0.51
comEC/celB	Streptococcus pneumoniae R6	51.701	98.658	0.51
comEC	Lactococcus lactis subsp. cremoris KW2	49.399	100	0.497