Detailed information NTG0495571

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: IOD66_RS09045
• Genome accession: NZ_CP063424
• Coordinates: 1937905..1938561 (+)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae strain APP5
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 1932905..1943561

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IOD66_RS09000 (IOD66_09015)	rplP	1932976..1933386 (-)	411	WP_005599294.1	50S ribosomal protein L16	-
IOD66_RS09005 (IOD66_09020)	rpsC	1933400..1934107 (-)	708	WP_005599293.1	30S ribosomal protein S3	-
IOD66_RS09010 (IOD66_09025)	rplV	1934126..1934458 (-)	333	WP_005599292.1	50S ribosomal protein L22	-
IOD66_RS09015 (IOD66_09030)	rpsS	1934469..1934744 (-)	276	WP_005539416.1	30S ribosomal protein S19	-
IOD66_RS09020 (IOD66_09035)	rplB	1934772..1935593 (-)	822	WP_005599291.1	50S ribosomal protein L2	-
IOD66_RS09025 (IOD66_09040)	rplW	1935614..1935919 (-)	306	WP_005599290.1	50S ribosomal protein L23	-
IOD66_RS09030 (IOD66_09045)	rplD	1935916..1936518 (-)	603	WP_005599282.1	50S ribosomal protein L4	-
IOD66_RS09035 (IOD66_09050)	rplC	1936534..1937160 (-)	627	WP_005599280.1	50S ribosomal protein L3	-
IOD66_RS09040 (IOD66_09055)	rpsJ	1937186..1937497 (-)	312	WP_001181005.1	30S ribosomal protein S10	-
IOD66_RS09045 (IOD66_09060)	sxy/tfoX	1937905..1938561 (+)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
IOD66_RS09050 (IOD66_09065)	fumC	1938716..1940110 (+)	1395	WP_005605803.1	class II fumarate hydratase	-
IOD66_RS09055 (IOD66_09070)	nagA	1940259..1941404 (-)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
IOD66_RS09060 (IOD66_09075)	nagB	1941456..1942259 (-)	804	WP_005599267.1	glucosamine-6-phosphate deaminase	-
IOD66_RS09065 (IOD66_09080)	nanA	1942309..1943187 (-)	879	WP_005599265.1	N-acetylneuraminate lyase	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=495571 IOD66_RS09045 WP_005609196.1 1937905..1938561(+) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain APP5]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=495571 IOD66_RS09045 WP_005609196.1 1937905..1938561(+) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain APP5]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376