Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiC   Type   Regulator
Locus tag   SPYALAB49_RS01375 Genome accession   NC_017596
Coordinates   257860..259362 (+) Length   500 a.a.
NCBI ID   WP_002992227.1    Uniprot ID   -
Organism   Streptococcus pyogenes Alab49     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 252860..264362
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYALAB49_RS01360 (SPYALAB49_000280) - 252913..254094 (-) 1182 WP_002992220.1 D-alanyl-D-alanine carboxypeptidase family protein -
  SPYALAB49_RS01365 (SPYALAB49_000281) pbp3 254262..255494 (-) 1233 WP_002991111.1 D-alanyl-D-alanine carboxypeptidase PBP3 -
  SPYALAB49_RS01370 (SPYALAB49_000282) amiA 255825..257795 (+) 1971 WP_014635281.1 peptide ABC transporter substrate-binding protein Regulator
  SPYALAB49_RS01375 (SPYALAB49_000283) amiC 257860..259362 (+) 1503 WP_002992227.1 ABC transporter permease Regulator
  SPYALAB49_RS01380 (SPYALAB49_000284) amiD 259362..260288 (+) 927 WP_002986004.1 oligopeptide ABC transporter permease OppC Regulator
  SPYALAB49_RS01385 (SPYALAB49_000285) amiE 260297..261367 (+) 1071 WP_002992231.1 ABC transporter ATP-binding protein Regulator
  SPYALAB49_RS01390 (SPYALAB49_000286) amiF 261360..262283 (+) 924 WP_002986000.1 ABC transporter ATP-binding protein Regulator
  SPYALAB49_RS10115 - 262321..262410 (-) 90 WP_109821088.1 IS3 family transposase -
  SPYALAB49_RS09740 (SPYALAB49_000287) - 262431..262670 (-) 240 WP_023605208.1 hypothetical protein -

Sequence

Protein


Download         Length: 500 a.a.        Molecular weight: 56121.46 Da        Isoelectric Point: 10.2222

>NTDB_id=49518 SPYALAB49_RS01375 WP_002992227.1 257860..259362(+) (amiC) [Streptococcus pyogenes Alab49]
MKKYILNRIMRSLVSVVLVTALTYTIVYTLVPTSLIFKQDPNYNKMTTTPDKKVAYENLTFQRMGYVNYFSSKELKDNAS
KVDSSVTTEATSANKAIYEKYIDSLGNGWQLKRFPTSKQFYAIRNIPIYERVWNFFSNLVVIDHPWKIQDKDNPKLARYI
RLEKDKSVGWSLVGSGTKHKYLLYTNGKFPYLHQNFVTLNLGTSYPTYSNIPVLQVISQGQGRTALQDVTFPSGVTKKSS
VDIYSRSYKNPKSLDDITKVNYGKGDSYTKTINNYVDPSMIHNSFVIGFFGVMFSYIVGLPLGLFMARFKNTYFDRFSTA
TMTFMLALPSIAVIYVVRFLGGMAGLPDSFPMLGASDPKSYILPALILGILNIPTTVIWFRRYLVDLQASDWVRFARSKG
LSESEIYRGHLFKNAMVPIVSGVPASIILAIGGATLTETVFAFPGMGKMLIDSIKSANNSMIVGLTFIFTVLSIVSLLLG
DIVMTLVDPRIKLSTKKGGK

Nucleotide


Download         Length: 1503 bp        

>NTDB_id=49518 SPYALAB49_RS01375 WP_002992227.1 257860..259362(+) (amiC) [Streptococcus pyogenes Alab49]
ATGAAAAAATACATTTTAAACCGTATCATGCGATCGTTAGTGTCGGTAGTTTTGGTAACGGCTTTAACATACACCATCGT
ATATACTCTAGTACCTACCAGCCTTATCTTTAAACAAGACCCTAATTATAATAAAATGACAACAACACCAGATAAAAAAG
TAGCGTATGAAAATCTAACTTTTCAACGTATGGGTTATGTCAATTATTTTTCAAGCAAAGAATTAAAAGATAATGCTTCT
AAAGTAGATAGTAGTGTAACGACAGAAGCAACTAGTGCTAACAAAGCTATCTATGAGAAGTATATTGATTCTCTTGGCAA
TGGCTGGCAGCTAAAACGCTTCCCCACTAGCAAACAGTTTTATGCAATTCGCAATATTCCTATTTACGAACGTGTTTGGA
ACTTTTTCTCAAATCTAGTTGTTATTGATCACCCTTGGAAGATTCAGGATAAAGACAATCCAAAATTAGCTAGGTATATT
CGTCTAGAAAAAGATAAATCAGTTGGCTGGTCACTTGTTGGTTCGGGGACAAAACATAAATATCTCCTCTACACTAACGG
AAAATTTCCTTATCTTCACCAAAACTTTGTTACCCTAAACTTAGGAACATCTTACCCAACATACAGCAATATTCCTGTTC
TTCAGGTTATTTCACAAGGGCAAGGACGAACAGCTCTTCAAGATGTGACCTTCCCATCAGGTGTCACTAAGAAATCGTCA
GTGGATATCTATAGCCGTAGCTACAAAAATCCAAAATCATTGGATGATATCACCAAGGTAAACTATGGTAAGGGAGATTC
CTACACTAAAACCATCAATAATTATGTCGACCCATCAATGATTCACAATTCTTTTGTAATTGGTTTTTTTGGTGTTATGT
TTTCCTATATCGTTGGTTTGCCTCTTGGTTTATTTATGGCTCGGTTTAAAAATACCTATTTTGACCGTTTCTCAACAGCG
ACCATGACCTTCATGCTTGCTTTACCAAGTATTGCTGTTATCTATGTTGTTCGCTTCCTAGGCGGCATGGCTGGTTTACC
AGATAGTTTCCCAATGCTAGGGGCATCTGATCCTAAATCTTATATTTTACCAGCCCTTATTTTAGGAATTTTAAATATTC
CAACTACGGTTATCTGGTTCCGTCGCTATCTTGTTGACCTTCAGGCCAGTGATTGGGTACGTTTTGCGCGTTCAAAAGGA
TTATCAGAATCTGAAATTTACAGAGGGCATCTCTTCAAAAATGCCATGGTCCCAATTGTGTCAGGGGTTCCTGCAAGTAT
TATCCTTGCTATTGGTGGTGCAACCTTAACAGAGACTGTCTTTGCCTTCCCGGGTATGGGTAAAATGTTAATTGATTCTA
TTAAATCTGCTAACAATTCTATGATTGTTGGATTAACCTTTATCTTCACTGTCTTGTCAATTGTTTCACTTTTACTAGGA
GATATTGTCATGACCCTTGTCGATCCACGTATTAAATTGTCAACAAAAAAAGGAGGTAAGTAA

Domains

Predicted by InterproScan.

Binding-protein-dependent transport system inner membrane component (BPD_transp_1)

(299-492)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiC Streptococcus salivarius strain HSISS4

59.6

100

0.596
  amiC Streptococcus thermophilus LMD-9

59.2

100

0.592
  amiC Streptococcus thermophilus LMG 18311

59.2

100

0.592

Multiple sequence alignment