Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   IPV48_RS25335 Genome accession   NZ_CP063386
Coordinates   5409204..5410541 (+) Length   445 a.a.
NCBI ID   WP_003110427.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain ST1076_d118limb1     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 5404204..5415541
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IPV48_RS25310 (IPV48_25305) pgeF 5404347..5405075 (-) 729 WP_015503650.1 peptidoglycan editing factor PgeF -
  IPV48_RS25315 (IPV48_25310) rluD 5405072..5406034 (-) 963 WP_003094686.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  IPV48_RS25320 (IPV48_25315) - 5406180..5407205 (+) 1026 WP_003102590.1 outer membrane protein assembly factor BamD -
  IPV48_RS25325 (IPV48_25320) - 5407362..5407607 (+) 246 WP_014603563.1 PP0621 family protein -
  IPV48_RS25330 (IPV48_25325) pilS 5407597..5409189 (+) 1593 WP_003110428.1 two-component system sensor histidine kinase PilS Regulator
  IPV48_RS25335 (IPV48_25330) pilR 5409204..5410541 (+) 1338 WP_003110427.1 two-component system response regulator PilR Regulator
  IPV48_RS25340 (IPV48_25335) thiO 5410587..5411681 (-) 1095 WP_003134931.1 glycine oxidase ThiO -
  IPV48_RS25345 (IPV48_25340) - 5411816..5412325 (+) 510 WP_015503652.1 Tfp pilus assembly protein FimT/FimU -
  IPV48_RS25350 (IPV48_25345) - 5412431..5412937 (+) 507 WP_003094696.1 Tfp pilus assembly protein FimT/FimU -
  IPV48_RS25355 (IPV48_25350) pilV 5412928..5413485 (+) 558 WP_003094697.1 type 4a pilus minor pilin PilV Machinery gene
  IPV48_RS25360 (IPV48_25355) pilW 5413482..5414306 (+) 825 WP_003094698.1 type 4a pilus minor pilin PilW -
  IPV48_RS25365 (IPV48_25360) pilX 5414303..5414890 (+) 588 WP_003094700.1 type 4a pilus minor pilin PilX -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49723.03 Da        Isoelectric Point: 5.8638

>NTDB_id=495064 IPV48_RS25335 WP_003110427.1 5409204..5410541(+) (pilR) [Pseudomonas aeruginosa strain ST1076_d118limb1]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLADRI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=495064 IPV48_RS25335 WP_003110427.1 5409204..5410541(+) (pilR) [Pseudomonas aeruginosa strain ST1076_d118limb1]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAGCTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAAGCCGCCAGCGGTGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGATCGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGTAACGTCCGCGAGCTGGAGAATATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAACCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCGGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAAGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGTTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

Sigma-54 interaction domain (Sigma54_activat)

(135-301)

Response regulator receiver domain (Response_reg)

(7-115)

Bacterial regulatory protein, Fis family (HTH_8)

(402-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

99.775

100

0.998
  pilR Acinetobacter baumannii strain A118

51.198

100

0.528
  luxO Vibrio cholerae strain A1552

38.17

100

0.384