Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   IM723_RS03535 Genome accession   NZ_CP063275
Coordinates   664622..665362 (+) Length   246 a.a.
NCBI ID   WP_096811959.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain DMST-H2     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 659622..670362
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IM723_RS03515 - 661152..661514 (+) 363 WP_039671040.1 SAG1252 family conjugative relaxosome accessory protein -
  IM723_RS03520 mobC 661517..661882 (+) 366 WP_039671039.1 plasmid mobilization relaxosome protein MobC -
  IM723_RS03525 - 661869..663752 (+) 1884 WP_111679172.1 SAG1250 family conjugative relaxase -
  IM723_RS03530 - 664279..664620 (+) 342 WP_024404826.1 LytTR family DNA-binding domain-containing protein -
  IM723_RS03535 comE/blpR 664622..665362 (+) 741 WP_096811959.1 response regulator transcription factor Regulator
  IM723_RS03540 - 665373..666713 (+) 1341 WP_039671036.1 GHKL domain-containing protein -
  IM723_RS03545 - 666761..666916 (-) 156 WP_096811960.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  IM723_RS03550 - 667015..668376 (-) 1362 WP_173940475.1 bacteriocin secretion accessory protein -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28894.15 Da        Isoelectric Point: 7.2201

>NTDB_id=494159 IM723_RS03535 WP_096811959.1 664622..665362(+) (comE/blpR) [Streptococcus thermophilus strain DMST-H2]
MNIFVMEDDFMQQARIEKIITKLLEKHNIVPKKFEISGKPHQLLQAIEEKGVHQLFFLDIEIKEDELKGLQVAKQIREID
PYASIVFVTTHSEFMPLSFRYQVSALDYIDKELGVTEFESRIEAALLHTHNKDNSAVSDDSFYFKSKYAQVQYPFNEVYY
IETSPRPHRVILYTKTDRMEFTASLSDILKQDKRLVQCHRSFAINPRNVVKVDRNEKQIYFPNGATCFISRQKLESTLAV
IDRLHR

Nucleotide


Download         Length: 741 bp        

>NTDB_id=494159 IM723_RS03535 WP_096811959.1 664622..665362(+) (comE/blpR) [Streptococcus thermophilus strain DMST-H2]
ATGAATATCTTTGTAATGGAAGATGATTTTATGCAACAAGCGAGAATTGAGAAGATTATTACTAAGCTGTTAGAAAAGCA
CAACATCGTTCCGAAAAAATTTGAAATTTCAGGAAAACCTCATCAGCTACTTCAAGCAATAGAAGAAAAAGGAGTACATC
AGCTCTTCTTTTTAGATATTGAGATTAAGGAAGACGAACTAAAAGGACTTCAAGTCGCTAAACAAATTAGAGAGATTGAC
CCTTATGCTAGTATTGTTTTTGTGACAACACACTCCGAGTTTATGCCCTTATCTTTCAGGTACCAGGTATCTGCCTTGGA
CTATATTGACAAAGAGCTTGGAGTTACCGAATTTGAATCGCGAATAGAAGCAGCTTTACTTCATACTCACAATAAGGACA
ATAGCGCCGTATCGGATGATTCATTCTATTTTAAGTCCAAATATGCTCAAGTACAATACCCATTCAATGAAGTGTACTAC
ATCGAGACTTCTCCCCGCCCTCATCGTGTTATCCTTTATACCAAGACAGACCGAATGGAGTTCACAGCAAGTTTGTCAGA
CATTTTGAAACAAGATAAACGACTTGTACAATGTCATCGTTCGTTTGCAATCAATCCGAGGAATGTTGTTAAAGTGGATA
GAAATGAAAAACAGATCTACTTTCCTAATGGAGCCACCTGTTTTATTTCAAGGCAAAAGCTAGAATCAACTTTAGCTGTT
ATTGATAGACTGCATAGATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.719

98.374

0.528
  comE/comE1 Streptococcus equinus JB1

41.423

97.154

0.402
  comE/comE2 Streptococcus equinus JB1

36.475

99.187

0.362