Detailed information    

insolico Bioinformatically predicted

Overview

Name   degS   Type   Regulator
Locus tag   IMZ18_RS21610 Genome accession   NZ_CP063151
Coordinates   4087434..4088591 (+) Length   385 a.a.
NCBI ID   WP_003227983.1    Uniprot ID   A0A199WDV9
Organism   Bacillus subtilis subsp. subtilis strain CMIN-4     
Function   phosphorylation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 4082434..4093591
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IMZ18_RS21580 (IMZ18_21580) - 4082648..4083427 (-) 780 WP_014481059.1 hypothetical protein -
  IMZ18_RS21585 (IMZ18_21585) - 4083503..4083955 (-) 453 WP_014481058.1 hypothetical protein -
  IMZ18_RS21590 (IMZ18_21590) - 4084006..4084461 (-) 456 WP_014481057.1 hypothetical protein -
  IMZ18_RS21595 (IMZ18_21595) - 4084510..4084965 (-) 456 WP_041516563.1 hypothetical protein -
  IMZ18_RS21600 (IMZ18_21600) - 4085572..4086564 (-) 993 WP_014481056.1 LCP family protein -
  IMZ18_RS21605 (IMZ18_21605) - 4086564..4087217 (-) 654 WP_014481055.1 YigZ family protein -
  IMZ18_RS21610 (IMZ18_21610) degS 4087434..4088591 (+) 1158 WP_003227983.1 two-component sensor histidine kinase DegS Regulator
  IMZ18_RS21615 (IMZ18_21615) degU 4088674..4089363 (+) 690 WP_014481054.1 two-component system response regulator DegU Regulator
  IMZ18_RS21620 (IMZ18_21620) fakBA 4089461..4090306 (+) 846 WP_014481053.1 DegV family protein -
  IMZ18_RS21625 (IMZ18_21625) comFA 4090413..4091804 (+) 1392 WP_014481052.1 ATP-dependent helicase ComFA Machinery gene
  IMZ18_RS21630 (IMZ18_21630) comFB 4091864..4092160 (+) 297 WP_003227989.1 late competence protein ComFB -
  IMZ18_RS21635 (IMZ18_21635) comFC 4092124..4092846 (+) 723 WP_014481051.1 comF operon protein ComFC Machinery gene
  IMZ18_RS21640 (IMZ18_21640) yvyF 4092919..4093338 (+) 420 WP_014481050.1 TIGR03826 family flagellar region protein -

Sequence

Protein


Download         Length: 385 a.a.        Molecular weight: 44957.76 Da        Isoelectric Point: 6.2957

>NTDB_id=493510 IMZ18_RS21610 WP_003227983.1 4087434..4088591(+) (degS) [Bacillus subtilis subsp. subtilis strain CMIN-4]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide


Download         Length: 1158 bp        

>NTDB_id=493510 IMZ18_RS21610 WP_003227983.1 4087434..4088591(+) (degS) [Bacillus subtilis subsp. subtilis strain CMIN-4]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAAGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATCGAGCTTGGCGATAAACTTGAAGTGCAAACCCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGGATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTACGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

Histidine kinase (HisKA_3)

(180-248)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(291-384)

Sensor protein DegS (DegS)

(12-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A199WDV9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  degS Bacillus subtilis subsp. subtilis str. 168

100

100

1