Detailed information NTG0049343

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SPNINV200_RS09705
• Genome accession: NC_017593
• Coordinates: 1833720..1834730 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae INV200
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1828720..1839730

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPNINV200_RS09680 (SPNINV200_18060)	-	1830066..1830359 (-)	294	WP_000977363.1	hypothetical protein	-
SPNINV200_RS09685 (SPNINV200_18070)	-	1830521..1830973 (+)	453	WP_000079148.1	universal stress protein	-
SPNINV200_RS09690 (SPNINV200_18080)	-	1831008..1832396 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
SPNINV200_RS09695 (SPNINV200_18090)	-	1832462..1833424 (+)	963	WP_001124777.1	asparaginase	-
SPNINV200_RS09700	-	1833453..1833656 (-)	204	WP_001813553.1	hypothetical protein	-
SPNINV200_RS09705 (SPNINV200_18100)	ccpA	1833720..1834730 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
SPNINV200_RS09710 (SPNINV200_18110)	-	1835154..1835753 (-)	600	WP_000866698.1	response regulator transcription factor	-
SPNINV200_RS09715 (SPNINV200_18120)	-	1835754..1836851 (-)	1098	WP_000893537.1	sensor histidine kinase	-
SPNINV200_RS09720 (SPNINV200_18130)	-	1836851..1837588 (-)	738	WP_001809843.1	ABC transporter permease	-
SPNINV200_RS09725 (SPNINV200_18140)	-	1837590..1838474 (-)	885	WP_000219347.1	ABC transporter ATP-binding protein	-
SPNINV200_RS09730 (SPNINV200_18150)	-	1838461..1838655 (-)	195	WP_000820187.1	hypothetical protein	-
SPNINV200_RS12545 (SPNINV200_18160)	-	1838652..1838858 (-)	207	Protein_1822	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=49343 SPNINV200_RS09705 WP_000990607.1 1833720..1834730(-) (ccpA) [Streptococcus pneumoniae INV200]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=49343 SPNINV200_RS09705 WP_000990607.1 1833720..1834730(-) (ccpA) [Streptococcus pneumoniae INV200]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568