Detailed information NTG0493427

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: IMY14_RS18960
• Genome accession: NZ_CP063150
• Coordinates: 3636170..3637327 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus subtilis strain s-16
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3631170..3642327

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IMY14_RS18930	yvyF	3631423..3631842 (-)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-
IMY14_RS18935	comFC	3631916..3632638 (-)	723	WP_047183272.1	comF operon protein ComFC	Machinery gene
IMY14_RS18940	comFB	3632602..3632898 (-)	297	WP_015483764.1	late competence protein ComFB	-
IMY14_RS18945	comFA	3632958..3634349 (-)	1392	WP_047183273.1	ATP-dependent helicase ComFA	Machinery gene
IMY14_RS18950	fakBA	3634455..3635300 (-)	846	WP_047183274.1	DegV family protein	-
IMY14_RS18955	degU	3635398..3636087 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
IMY14_RS18960	degS	3636170..3637327 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
IMY14_RS18965	yvyE	3637544..3638197 (+)	654	WP_003227979.1	YigZ family protein	-
IMY14_RS18970	tagV	3638197..3639372 (+)	1176	WP_047183275.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
IMY14_RS18975	tagO	3639445..3640521 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
IMY14_RS18980	tuaH	3640666..3641859 (-)	1194	WP_080344290.1	glycosyltransferase family 1 protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=493427 IMY14_RS18960 WP_003227983.1 3636170..3637327(-) (degS) [Bacillus subtilis strain s-16]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=493427 IMY14_RS18960 WP_003227983.1 3636170..3637327(-) (degS) [Bacillus subtilis strain s-16]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATTGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATCGAGCTTGGCGATAAACTTGAAGTGCAAACCCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAGATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTACGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1