Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   INP91_RS08515 Genome accession   NZ_CP063123
Coordinates   1765951..1766619 (-) Length   222 a.a.
NCBI ID   WP_049369445.1    Uniprot ID   A0A369YVV2
Organism   Haemophilus parainfluenzae strain M1C120_2     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1760951..1771619
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP91_RS08495 (INP91_08490) - 1761257..1762123 (-) 867 WP_005698439.1 MurR/RpiR family transcriptional regulator -
  INP91_RS08500 (INP91_08495) - 1762116..1763054 (-) 939 WP_070868997.1 N-acetylmannosamine kinase -
  INP91_RS08505 (INP91_08500) - 1763066..1763755 (-) 690 WP_197545813.1 N-acetylmannosamine-6-phosphate 2-epimerase -
  INP91_RS08510 (INP91_08505) nagE 1763974..1765440 (+) 1467 WP_197545814.1 N-acetylglucosamine-specific PTS transporter subunit IIBC -
  INP91_RS08515 (INP91_08510) crp 1765951..1766619 (-) 669 WP_049369445.1 cAMP-activated global transcriptional regulator CRP Regulator
  INP91_RS08520 (INP91_08515) - 1766636..1766854 (-) 219 WP_070712917.1 YheU family protein -
  INP91_RS08525 (INP91_08520) slmA 1766876..1767529 (-) 654 WP_193451371.1 nucleoid occlusion factor SlmA -
  INP91_RS08530 (INP91_08525) dut 1767533..1767988 (-) 456 WP_193451372.1 dUTP diphosphatase -
  INP91_RS08535 (INP91_08530) coaBC 1768061..1769263 (-) 1203 WP_193451373.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  INP91_RS08540 (INP91_08535) radC 1769467..1770132 (+) 666 WP_193451458.1 RadC family protein -
  INP91_RS08545 (INP91_08540) rpmB 1770351..1770587 (+) 237 WP_005599762.1 50S ribosomal protein L28 -
  INP91_RS08550 (INP91_08545) rpmG 1770599..1770769 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 25146.92 Da        Isoelectric Point: 6.9081

>NTDB_id=493179 INP91_RS08515 WP_049369445.1 1765951..1766619(-) (crp) [Haemophilus parainfluenzae strain M1C120_2]
MSENVELLEEQKPQDDDQQRDPALDWFLTHCHLHKYPAKSTLIHAGEDANILYFLIKGTVMVSSKDDEGKEMILSYLGAG
QFFGEAGLFDEGSKRSAWVKTKTPCEIAEISYKKYRQLIQINPEILMFLTSQLSKRLQNTSRQVTNLAFLDVAGRIAQAL
MHLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGTR

Nucleotide


Download         Length: 669 bp        

>NTDB_id=493179 INP91_RS08515 WP_049369445.1 1765951..1766619(-) (crp) [Haemophilus parainfluenzae strain M1C120_2]
ATGTCAGAAAATGTAGAATTATTAGAAGAACAAAAGCCGCAGGACGATGATCAGCAACGTGATCCTGCTCTGGATTGGTT
CCTAACTCACTGTCATTTACATAAATATCCGGCAAAATCGACCTTAATCCATGCAGGGGAAGATGCCAATATTTTATATT
TCTTAATTAAAGGAACCGTGATGGTTTCATCGAAAGATGATGAAGGCAAAGAGATGATTTTATCTTATTTAGGTGCTGGA
CAATTTTTTGGTGAAGCAGGTTTATTTGATGAAGGCTCGAAACGTTCTGCTTGGGTGAAAACGAAAACCCCTTGTGAAAT
TGCAGAAATTTCCTATAAAAAATATCGTCAGCTTATTCAAATTAATCCTGAGATTTTAATGTTCCTTACTTCTCAGTTAT
CAAAGCGCTTGCAAAATACATCTCGACAAGTGACTAACTTGGCCTTTTTAGATGTGGCAGGCCGTATTGCTCAGGCGCTT
ATGCATTTAGCAAAACAACCTGAAGCCATGACGCATCCTGATGGTATGCAAATTAAAATTACGCGTCAGGAAATAGGCCA
GATGGTAGGTTGTTCGCGTGAAACTGTCGGGCGAATCATTAAGATGCTGGAAGATCAAAATCTAATCCATGCGCACGGCA
AAACCATTGTGGTTTACGGCACAAGATAG

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(34-120)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(154-218)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A369YVV2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

90.909

94.144

0.856
  crp Vibrio cholerae strain A1552

73.529

91.892

0.676
  crp Acinetobacter baumannii D1279779

46.231

89.64

0.414