Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   INP92_RS00055 Genome accession   NZ_CP063122
Coordinates   11287..11955 (-) Length   222 a.a.
NCBI ID   WP_049369445.1    Uniprot ID   A0A369YVV2
Organism   Haemophilus parainfluenzae strain M1C125_4     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6287..16955
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP92_RS00035 (INP92_00035) - 6593..7459 (-) 867 WP_014064022.1 MurR/RpiR family transcriptional regulator -
  INP92_RS00040 (INP92_00040) - 7452..8390 (-) 939 WP_197554189.1 N-acetylmannosamine kinase -
  INP92_RS00045 (INP92_00045) - 8402..9091 (-) 690 WP_197554192.1 N-acetylmannosamine-6-phosphate 2-epimerase -
  INP92_RS00050 (INP92_00050) nagE 9310..10776 (+) 1467 WP_197545814.1 N-acetylglucosamine-specific PTS transporter subunit IIBC -
  INP92_RS00055 (INP92_00055) crp 11287..11955 (-) 669 WP_049369445.1 cAMP-activated global transcriptional regulator CRP Regulator
  INP92_RS00060 (INP92_00060) - 11972..12190 (-) 219 WP_197555047.1 YheU family protein -
  INP92_RS00065 (INP92_00065) slmA 12212..12865 (-) 654 WP_005698358.1 nucleoid occlusion factor SlmA -
  INP92_RS00070 (INP92_00070) dut 12869..13324 (-) 456 WP_197554195.1 dUTP diphosphatase -
  INP92_RS00075 (INP92_00075) coaBC 13398..14600 (-) 1203 WP_197554198.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  INP92_RS00080 (INP92_00080) radC 14803..15468 (+) 666 WP_197554201.1 RadC family protein -
  INP92_RS00085 (INP92_00085) rpmB 15687..15923 (+) 237 WP_005599762.1 50S ribosomal protein L28 -
  INP92_RS00090 (INP92_00090) rpmG 15935..16105 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 25146.92 Da        Isoelectric Point: 6.9081

>NTDB_id=493124 INP92_RS00055 WP_049369445.1 11287..11955(-) (crp) [Haemophilus parainfluenzae strain M1C125_4]
MSENVELLEEQKPQDDDQQRDPALDWFLTHCHLHKYPAKSTLIHAGEDANILYFLIKGTVMVSSKDDEGKEMILSYLGAG
QFFGEAGLFDEGSKRSAWVKTKTPCEIAEISYKKYRQLIQINPEILMFLTSQLSKRLQNTSRQVTNLAFLDVAGRIAQAL
MHLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGTR

Nucleotide


Download         Length: 669 bp        

>NTDB_id=493124 INP92_RS00055 WP_049369445.1 11287..11955(-) (crp) [Haemophilus parainfluenzae strain M1C125_4]
ATGTCAGAAAATGTAGAATTATTAGAAGAACAAAAGCCCCAGGACGATGATCAGCAACGTGATCCTGCTCTGGATTGGTT
CCTAACCCACTGTCATTTACATAAATATCCGGCTAAATCTACCTTAATTCATGCGGGGGAAGATGCCAATATTTTATATT
TCTTAATTAAAGGAACGGTGATGGTTTCATCGAAAGATGATGAAGGCAAAGAGATGATTTTATCTTATTTAGGTGCTGGA
CAATTTTTTGGTGAAGCAGGTTTATTTGATGAAGGCTCGAAACGTTCTGCTTGGGTGAAAACGAAAACCCCTTGTGAAAT
TGCAGAAATTTCCTATAAAAAATATCGTCAGCTTATTCAAATTAATCCTGAGATTTTAATGTTCCTTACTTCTCAGTTAT
CAAAGCGCTTGCAAAATACATCTCGACAAGTGACTAACTTGGCCTTTTTAGATGTGGCAGGCCGTATTGCTCAGGCGCTT
ATGCATTTAGCAAAACAACCTGAAGCCATGACGCATCCTGATGGTATGCAAATTAAAATTACGCGTCAGGAAATAGGCCA
GATGGTAGGTTGTTCGCGTGAAACTGTCGGGCGAATCATTAAGATGCTGGAAGATCAAAATCTAATCCATGCGCACGGCA
AAACCATTGTGGTTTACGGCACAAGATAG

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(34-120)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(154-218)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A369YVV2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

90.909

94.144

0.856
  crp Vibrio cholerae strain A1552

73.529

91.892

0.676
  crp Acinetobacter baumannii D1279779

46.231

89.64

0.414