Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   INP93_RS00055 Genome accession   NZ_CP063121
Coordinates   11283..11951 (-) Length   222 a.a.
NCBI ID   WP_049369445.1    Uniprot ID   A0A369YVV2
Organism   Haemophilus parainfluenzae strain M1C130_2     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6283..16951
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP93_RS00035 (INP93_00035) - 6590..7456 (-) 867 WP_014064022.1 MurR/RpiR family transcriptional regulator -
  INP93_RS00040 (INP93_00040) - 7449..8387 (-) 939 WP_197544798.1 N-acetylmannosamine kinase -
  INP93_RS00045 (INP93_00045) - 8399..9088 (-) 690 WP_049372873.1 N-acetylmannosamine-6-phosphate 2-epimerase -
  INP93_RS00050 (INP93_00050) nagE 9306..10772 (+) 1467 WP_197544799.1 N-acetylglucosamine-specific PTS transporter subunit IIBC -
  INP93_RS00055 (INP93_00055) crp 11283..11951 (-) 669 WP_049369445.1 cAMP-activated global transcriptional regulator CRP Regulator
  INP93_RS00060 (INP93_00060) - 11968..12186 (-) 219 WP_005695554.1 YheU family protein -
  INP93_RS00065 (INP93_00065) slmA 12208..12861 (-) 654 WP_005698358.1 nucleoid occlusion factor SlmA -
  INP93_RS00070 (INP93_00070) dut 12865..13320 (-) 456 WP_197544800.1 dUTP diphosphatase -
  INP93_RS00075 (INP93_00075) coaBC 13394..14596 (-) 1203 WP_197544801.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  INP93_RS00080 (INP93_00080) radC 14800..15465 (+) 666 WP_049371887.1 RadC family protein -
  INP93_RS00085 (INP93_00085) rpmB 15684..15920 (+) 237 WP_005599762.1 50S ribosomal protein L28 -
  INP93_RS00090 (INP93_00090) rpmG 15932..16102 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 25146.92 Da        Isoelectric Point: 6.9081

>NTDB_id=493092 INP93_RS00055 WP_049369445.1 11283..11951(-) (crp) [Haemophilus parainfluenzae strain M1C130_2]
MSENVELLEEQKPQDDDQQRDPALDWFLTHCHLHKYPAKSTLIHAGEDANILYFLIKGTVMVSSKDDEGKEMILSYLGAG
QFFGEAGLFDEGSKRSAWVKTKTPCEIAEISYKKYRQLIQINPEILMFLTSQLSKRLQNTSRQVTNLAFLDVAGRIAQAL
MHLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGTR

Nucleotide


Download         Length: 669 bp        

>NTDB_id=493092 INP93_RS00055 WP_049369445.1 11283..11951(-) (crp) [Haemophilus parainfluenzae strain M1C130_2]
ATGTCAGAAAATGTCGAATTATTAGAAGAACAAAAGCCGCAGGACGATGATCAGCAGCGAGATCCTGCTCTGGATTGGTT
CCTTACTCACTGTCATTTACATAAATATCCAGCAAAATCGACCTTAATTCATGCGGGTGAAGATGCCAATATTTTATATT
TCTTAATTAAAGGAACCGTGATGGTTTCATCGAAAGATGATGAAGGCAAAGAGATGATTTTATCTTATTTAGGTGCCGGA
CAATTTTTTGGTGAAGCGGGTTTATTTGATGAAGGCTCGAAACGTTCTGCTTGGGTGAAAACGAAAACCCCTTGTGAAAT
TGCAGAAATTTCCTATAAAAAATATCGTCAGCTTATCCAAATTAATCCTGAGATTTTAATGTTCCTTACTTCTCAGTTAT
CAAAACGCTTGCAAAATACATCGCGACAAGTGACTAACTTGGCCTTTTTAGATGTGGCAGGGCGTATTGCTCAGGCGCTT
ATGCATTTAGCAAAACAACCTGAAGCGATGACGCATCCTGATGGTATGCAGATTAAAATTACACGTCAGGAAATCGGTCA
AATGGTAGGTTGTTCGCGTGAAACCGTAGGGCGAATCATTAAGATGCTGGAAGATCAAAATCTCATTCATGCACACGGCA
AAACCATTGTGGTTTATGGCACAAGATAG

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(34-120)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(154-218)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A369YVV2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

90.909

94.144

0.856
  crp Vibrio cholerae strain A1552

73.529

91.892

0.676
  crp Acinetobacter baumannii D1279779

46.231

89.64

0.414