Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   INP94_RS00055 Genome accession   NZ_CP063120
Coordinates   11293..11961 (-) Length   222 a.a.
NCBI ID   WP_049369445.1    Uniprot ID   A0A369YVV2
Organism   Haemophilus parainfluenzae strain M1C137_2     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6293..16961
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP94_RS00035 (INP94_00035) - 6590..7456 (-) 867 WP_005698439.1 MurR/RpiR family transcriptional regulator -
  INP94_RS00040 (INP94_00040) - 7449..8387 (-) 939 WP_197543630.1 N-acetylmannosamine kinase -
  INP94_RS00045 (INP94_00045) - 8399..9088 (-) 690 WP_197543631.1 N-acetylmannosamine-6-phosphate 2-epimerase -
  INP94_RS00050 (INP94_00050) nagE 9317..10783 (+) 1467 WP_197543632.1 N-acetylglucosamine-specific PTS transporter subunit IIBC -
  INP94_RS00055 (INP94_00055) crp 11293..11961 (-) 669 WP_049369445.1 cAMP-activated global transcriptional regulator CRP Regulator
  INP94_RS00060 (INP94_00060) - 11978..12196 (-) 219 WP_197543633.1 YheU family protein -
  INP94_RS00065 (INP94_00065) slmA 12218..12871 (-) 654 WP_049372870.1 nucleoid occlusion factor SlmA -
  INP94_RS00070 (INP94_00070) dut 12875..13330 (-) 456 WP_005698440.1 dUTP diphosphatase -
  INP94_RS00075 (INP94_00075) coaBC 13404..14606 (-) 1203 WP_197543634.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  INP94_RS00080 (INP94_00080) radC 14811..15476 (+) 666 WP_197543635.1 RadC family protein -
  INP94_RS00085 (INP94_00085) rpmB 15695..15931 (+) 237 WP_005599762.1 50S ribosomal protein L28 -
  INP94_RS00090 (INP94_00090) rpmG 15943..16113 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 25146.92 Da        Isoelectric Point: 6.9081

>NTDB_id=493061 INP94_RS00055 WP_049369445.1 11293..11961(-) (crp) [Haemophilus parainfluenzae strain M1C137_2]
MSENVELLEEQKPQDDDQQRDPALDWFLTHCHLHKYPAKSTLIHAGEDANILYFLIKGTVMVSSKDDEGKEMILSYLGAG
QFFGEAGLFDEGSKRSAWVKTKTPCEIAEISYKKYRQLIQINPEILMFLTSQLSKRLQNTSRQVTNLAFLDVAGRIAQAL
MHLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGTR

Nucleotide


Download         Length: 669 bp        

>NTDB_id=493061 INP94_RS00055 WP_049369445.1 11293..11961(-) (crp) [Haemophilus parainfluenzae strain M1C137_2]
ATGTCAGAAAATGTAGAATTATTAGAAGAACAAAAGCCGCAGGACGATGATCAACAACGTGATCCTGCTCTGGATTGGTT
CCTAACGCACTGCCATTTACATAAATATCCGGCAAAATCGACCTTAATTCATGCAGGGGAAGATGCGAATATTTTATATT
TCTTAATTAAAGGAACCGTGATGGTTTCATCGAAAGATGATGAAGGCAAAGAGATGATTTTATCTTATTTAGGTGCCGGA
CAATTTTTTGGTGAGGCAGGTTTATTTGATGAAGGCTCGAAACGTTCTGCTTGGGTGAAAACGAAAACCCCTTGTGAAAT
TGCGGAAATTTCCTATAAAAAATATCGTCAGCTTATTCAAATTAATCCTGAGATTTTAATGTTCCTTACTTCTCAGTTAT
CAAAACGCTTGCAAAACACGTCTCGACAAGTGACTAACTTGGCCTTTTTGGATGTGGCAGGGCGTATTGCTCAGGCGCTT
ATGCATTTAGCAAAACAGCCTGAAGCGATGACGCATCCTGATGGCATGCAGATTAAAATTACGCGTCAGGAAATCGGTCA
AATGGTGGGCTGTTCACGTGAAACCGTAGGGCGAATAATTAAGATGCTGGAAGATCAGAATCTCATTCATGCGCACGGCA
AAACCATTGTTGTTTACGGCACTCGATAG

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(34-120)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(154-218)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A369YVV2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

90.909

94.144

0.856
  crp Vibrio cholerae strain A1552

73.529

91.892

0.676
  crp Acinetobacter baumannii D1279779

46.231

89.64

0.414