Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   INP96_RS00055 Genome accession   NZ_CP063116
Coordinates   11288..11956 (-) Length   222 a.a.
NCBI ID   WP_049369445.1    Uniprot ID   A0A369YVV2
Organism   Haemophilus parainfluenzae strain M1C146_1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6288..16956
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP96_RS00035 (INP96_00035) - 6595..7461 (-) 867 WP_070582513.1 MurR/RpiR family transcriptional regulator -
  INP96_RS00040 (INP96_00040) - 7454..8392 (-) 939 WP_070582514.1 N-acetylmannosamine kinase -
  INP96_RS00045 (INP96_00045) - 8404..9093 (-) 690 WP_070582515.1 N-acetylmannosamine-6-phosphate 2-epimerase -
  INP96_RS00050 (INP96_00050) nagE 9320..10786 (+) 1467 WP_014064025.1 N-acetylglucosamine-specific PTS transporter subunit IIBC -
  INP96_RS00055 (INP96_00055) crp 11288..11956 (-) 669 WP_049369445.1 cAMP-activated global transcriptional regulator CRP Regulator
  INP96_RS00060 (INP96_00060) - 11973..12191 (-) 219 WP_197555863.1 YheU family protein -
  INP96_RS00065 (INP96_00065) slmA 12213..12866 (-) 654 WP_197555864.1 nucleoid occlusion factor SlmA -
  INP96_RS00070 (INP96_00070) dut 12870..13325 (-) 456 WP_197555865.1 dUTP diphosphatase -
  INP96_RS00075 (INP96_00075) coaBC 13399..14601 (-) 1203 WP_197555866.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  INP96_RS00080 (INP96_00080) radC 14807..15472 (+) 666 WP_197555867.1 RadC family protein -
  INP96_RS00085 (INP96_00085) rpmB 15691..15927 (+) 237 WP_005599762.1 50S ribosomal protein L28 -
  INP96_RS00090 (INP96_00090) rpmG 15939..16109 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 25146.92 Da        Isoelectric Point: 6.9081

>NTDB_id=492997 INP96_RS00055 WP_049369445.1 11288..11956(-) (crp) [Haemophilus parainfluenzae strain M1C146_1]
MSENVELLEEQKPQDDDQQRDPALDWFLTHCHLHKYPAKSTLIHAGEDANILYFLIKGTVMVSSKDDEGKEMILSYLGAG
QFFGEAGLFDEGSKRSAWVKTKTPCEIAEISYKKYRQLIQINPEILMFLTSQLSKRLQNTSRQVTNLAFLDVAGRIAQAL
MHLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGTR

Nucleotide


Download         Length: 669 bp        

>NTDB_id=492997 INP96_RS00055 WP_049369445.1 11288..11956(-) (crp) [Haemophilus parainfluenzae strain M1C146_1]
ATGTCAGAAAATGTAGAATTATTAGAAGAACAAAAGCCCCAGGACGATGATCAGCAACGTGATCCTGCTCTGGATTGGTT
CCTAACCCACTGTCATTTACATAAATATCCGGCAAAATCGACCTTAATTCATGCGGGGGAAGATGCCAATATTTTATATT
TCTTAATTAAAGGAACGGTGATGGTTTCATCGAAAGATGATGAAGGCAAAGAGATGATTTTATCTTATCTAGGTGCTGGA
CAGTTTTTTGGTGAAGCGGGTTTATTTGATGAAGGCTCGAAACGTTCTGCTTGGGTAAAAACGAAAACCCCTTGTGAAAT
TGCAGAAATTTCCTATAAAAAATATCGTCAGCTTATCCAAATTAATCCTGAGATTTTAATGTTCCTTACTTCTCAGTTAT
CAAAACGCTTGCAAAATACATCTCGACAAGTGACTAACCTGGCCTTTTTGGATGTGGCGGGGCGTATTGCTCAGGCGCTT
ATGCATCTAGCAAAACAACCTGAAGCCATGACTCATCCAGATGGCATGCAGATTAAAATTACGCGTCAGGAAATTGGTCA
AATGGTGGGCTGTTCACGTGAAACCGTAGGGCGAATAATTAAGATGCTGGAAGATCAAAATCTAATTCATGCGCACGGTA
AAACCATTGTGGTTTACGGCACTCGATAG

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(34-120)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(154-218)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A369YVV2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

90.909

94.144

0.856
  crp Vibrio cholerae strain A1552

73.529

91.892

0.676
  crp Acinetobacter baumannii D1279779

46.231

89.64

0.414