Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   KH969_RS13300 Genome accession   NZ_CP074701
Coordinates   2720580..2721212 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 702/18     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2715580..2726212
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KH969_RS13275 (KH969_13285) yheS 2715749..2717662 (+) 1914 WP_000634832.1 ABC transporter ATP-binding protein -
  KH969_RS13280 (KH969_13290) yheT 2717662..2718684 (+) 1023 WP_000057383.1 hydrolase -
  KH969_RS13285 (KH969_13295) yheU 2718678..2718896 (+) 219 WP_000907085.1 YheU family protein -
  KH969_RS13290 (KH969_13300) prkB 2718950..2719819 (+) 870 WP_001274680.1 phosphoribulokinase -
  KH969_RS13295 (KH969_13305) yhfA 2719874..2720278 (-) 405 WP_001148908.1 OsmC family protein -
  KH969_RS13300 (KH969_13310) crp 2720580..2721212 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  KH969_RS13305 (KH969_13315) yhfK 2721263..2723353 (+) 2091 WP_001296470.1 YccS/YhfK family putative transporter -
  KH969_RS13310 (KH969_13320) argD 2723416..2724639 (-) 1224 WP_000963789.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  KH969_RS13315 (KH969_13325) pabA 2724725..2725288 (-) 564 WP_000601860.1 aminodeoxychorismate synthase component 2 -
  KH969_RS13320 (KH969_13330) fic 2725320..2725922 (-) 603 WP_001280625.1 putative adenosine monophosphate-protein transferase Fic -
  KH969_RS13325 (KH969_13335) yhfG 2725912..2726079 (-) 168 WP_000736865.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=492019 KH969_RS13300 WP_000242755.1 2720580..2721212(+) (crp) [Escherichia coli strain 702/18]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=492019 KH969_RS13300 WP_000242755.1 2720580..2721212(+) (crp) [Escherichia coli strain 702/18]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467