Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   INV104_RS02575 Genome accession   NC_017591
Coordinates   498122..498859 (+) Length   245 a.a.
NCBI ID   WP_001219141.1    Uniprot ID   -
Organism   Streptococcus pneumoniae INV104     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 493122..503859
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INV104_RS13135 - 494052..494291 (-) 240 WP_001813906.1 hypothetical protein -
  INV104_RS02545 (INV104_04370) - 494453..494740 (-) 288 WP_000777753.1 hypothetical protein -
  INV104_RS02550 (INV104_04380) - 494750..495160 (-) 411 WP_001278304.1 HIT family protein -
  INV104_RS02555 (INV104_04390) pptA 495228..495959 (+) 732 WP_000889923.1 ABC transporter ATP-binding protein Regulator
  INV104_RS02560 (INV104_04400) - 495956..497005 (+) 1050 WP_000653751.1 ABC transporter permease -
  INV104_RS02565 (INV104_04410) - 497173..497502 (-) 330 WP_000132572.1 hypothetical protein -
  INV104_RS02570 (INV104_04420) - 497779..498117 (+) 339 WP_000682133.1 LytTR family DNA-binding domain-containing protein -
  INV104_RS02575 (INV104_04430) comE/blpR 498122..498859 (+) 738 WP_001219141.1 response regulator transcription factor Regulator
  INV104_RS02580 (INV104_04440) - 498873..500213 (+) 1341 WP_001099891.1 sensor histidine kinase -
  INV104_RS02585 (INV104_04450) blpC 500284..500412 (-) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  INV104_RS02590 (INV104_04460) - 500469..501830 (-) 1362 WP_001069076.1 bacteriocin secretion accessory protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28752.87 Da        Isoelectric Point: 6.2366

>NTDB_id=49148 INV104_RS02575 WP_001219141.1 498122..498859(+) (comE/blpR) [Streptococcus pneumoniae INV104]
MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=49148 INV104_RS02575 WP_001219141.1 498122..498859(+) (comE/blpR) [Streptococcus pneumoniae INV104]
ATGAGAATATTTGTTTTAGAGGATGATTTTTCCCAACAGACTAGGATTGAAACGACGATTGAGAAACTCTTGAAGGAACA
TCATATCACTCCCAGCTCTTTTGAGGTATTTGGCAAGCCAGACCAACTGCTGGCAGAGGTGCATGAGAAGGGGGCCCATC
AGCTATTCTTTTTGGATATTGAGATTCGAAATGAGGAGATGAAGGGTCTGGAAGTGGCTAGAAAGATTCGGGATCGGGAT
CCGTATGCCCTGATTGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCCTTTCGCTACCAAGTGTCTGCTCTGGA
CTATATTGATAAGGCCCTTTCGGCAGAGGAGTTTGAATCTCGTATCGAGACAGCCCTCCTCTATGCCAATGGTCAAGACA
GTAAAAGTCTAGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCTCAATTCCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACGTCCACAAGACCCCATCGTGTTATTCTCTATACCAAGACAGACAGGCTGGAATTTACAGCGAGTCTAGAGGA
GGTTCTCAAGCAGGAGCCTCGTCTCTTGCAGTGCCATCGCTCTTTTCTCATCAATCCTGCCAATGTGGTGCATTTAGATA
AGAAAGAAAAACTGCTTTTCTTTCCCAATGGTGGAAGTTGTCTAATCGCGCGTTATAAGGTCAGGGAAGTGTCTGAGGCT
ATTAATAACTTACACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.441

100

0.539
  comE/comE1 Streptococcus equinus JB1

43.038

96.735

0.416
  comE/comE2 Streptococcus equinus JB1

38.43

98.776

0.38

Multiple sequence alignment