Detailed information NTG0049129

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: MSA_RS10425
• Genome accession: NC_021486
• Coordinates: 2016498..2019074 (-)
• Length: 858 a.a.
• NCBI ID: WP_016481341.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae ILRI005
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2011498..2024074

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MSA_RS10400 (MSA_21510)	-	2011609..2012160 (-)	552	WP_000817341.1	DNA-3-methyladenine glycosylase I	-
MSA_RS10405 (MSA_21520)	ruvA	2012183..2012773 (-)	591	WP_000272490.1	Holliday junction branch migration protein RuvA	Machinery gene
MSA_RS10410 (MSA_21530)	-	2012775..2014007 (-)	1233	WP_016481339.1	MFS transporter	-
MSA_RS10415 (MSA_21540)	hexB	2014039..2016018 (-)	1980	WP_079269307.1	DNA mismatch repair endonuclease MutL	Machinery gene
MSA_RS10420 (MSA_21550)	-	2016238..2016441 (+)	204	WP_000191849.1	cold shock domain-containing protein	-
MSA_RS10425 (MSA_21560)	hexA	2016498..2019074 (-)	2577	WP_016481341.1	DNA mismatch repair protein MutS	Machinery gene
MSA_RS10430 (MSA_21570)	argR	2019131..2019568 (-)	438	WP_001033152.1	arginine repressor	-
MSA_RS10435 (MSA_21580)	argS	2019790..2021481 (+)	1692	WP_016481342.1	arginine--tRNA ligase	-
MSA_RS10440 (MSA_21590)	-	2021569..2021877 (+)	309	WP_016481343.1	bacteriocin immunity protein	-
MSA_RS10445 (MSA_21600)	-	2021904..2022776 (-)	873	WP_016481344.1	YitT family protein	-
MSA_RS10450 (MSA_21610)	-	2022884..2023828 (-)	945	WP_016481345.1	YitT family protein	-

Sequence

Protein

• Length: 858 a.a.
• Molecular weight: 97078.70 Da
• Isoelectric Point: 4.8155

>NTDB_id=49129 MSA_RS10425 WP_016481341.1 2016498..2019074(-) (hexA) [Streptococcus agalactiae ILRI005]
MAKPTISPGMQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNAEKPIPMAGVPYHSAQQYIDVLV
ELGYKVAIAEQMEDPKKAVGVVKREVVQVVTPGTVVESTKPDSANNFLVAIDSQDQQTFGLAYMDVSTGEFQATLLTDFE
SVRSEILNLKAREIVVGYQLTDEKNHLLTKQMNLLLSYEDERLNDIHLIDEQLTDLEISAAEKLLQYVHRTQKRELSHLQ
KVVHYEIKDYLQMSYATKNSLDLLENARTSKKHGSLYWLLDETKTAMGTRMLRTWIDRPLVSMNRIKERQDIIQVFLDYF
FERNDLTESLKGVYDIERLASRVSFGKANPKDLLQLGQTLSQIPRIKMILQSFNQPELDIIVNKIDTMPELESLINTAIA
PEAQATITEGNIIKSGFDKQLDNYRTVMREGTGWIADIEAKERAASGIGTLKIDYNKKDGYYFHVTNSNLSLVPEHFFRK
ATLKNSERYGTAELAKIEGEMLEAREQSSNLEYDIFMRVRAQVESYIKRLQELAKTIATVDVLQSLAVVAENYHYVRPKF
NDEHQIKIKNGRHATVEKVMGVQEYIPNSIYFDSQTDIQLITGPNMSGKSTYMRQLALTVIMAQMGGFVSADEVDLPVFD
AIFTRIGAADDLISGQSTFMVEMMEANQAVKRASDKSLILFDELGRGTATYDGMALAQSIIEYIHNRVRAKTMFATHYHE
LTDLSEQLTRLVNVHVATLERDGEVTFLHKIESGPADKSYGIHVAKIAGLPIDLLDRATDILSQLEADAVQLIVSPSQEA
VTADLNEELDSEKQQGQLSLFEEPSNAGRVIEELEAIDIMNLTPMQAMNAIFDLKKLL

Nucleotide

• Length: 2577 bp

>NTDB_id=49129 MSA_RS10425 WP_016481341.1 2016498..2019074(-) (hexA) [Streptococcus agalactiae ILRI005]
ATGGCCAAGCCAACGATATCACCGGGAATGCAACAGTATCTGGATATAAAAGAGAATTATCCAGATGCTTTTTTGCTTTT
TAGAATGGGTGATTTTTATGAATTATTTTATGATGATGCGGTAAAAGCAGCACAAATCCTGGAAATTAGCTTGACTAGTC
GAAATAAGAACGCAGAAAAGCCAATCCCAATGGCAGGAGTTCCCTATCACTCAGCTCAACAGTATATTGACGTTTTAGTT
GAATTAGGTTACAAAGTAGCCATTGCTGAGCAGATGGAAGATCCTAAAAAAGCTGTGGGAGTGGTCAAGCGTGAGGTAGT
GCAAGTTGTTACCCCGGGAACGGTTGTGGAGTCAACGAAGCCGGATAGTGCTAATAATTTCTTAGTAGCGATTGATTCGC
AAGATCAACAAACATTTGGTCTAGCATATATGGATGTCTCAACTGGAGAGTTTCAGGCAACCCTTTTAACAGATTTTGAG
TCCGTCCGTAGTGAAATACTAAATTTAAAAGCTCGTGAGATTGTAGTAGGATATCAATTGACGGACGAAAAAAATCACCT
ACTGACGAAGCAGATGAACTTGCTTTTATCATACGAAGACGAACGACTTAATGATATTCATTTGATTGATGAACAGTTAA
CTGATTTGGAAATATCTGCTGCGGAAAAACTTTTACAATATGTGCATAGAACACAAAAGCGTGAACTTAGTCATTTACAG
AAAGTAGTTCATTATGAAATAAAGGACTATTTACAAATGTCATATGCAACAAAAAATAGTCTAGATTTACTGGAGAACGC
TAGAACAAGCAAGAAGCACGGAAGTCTTTACTGGTTGTTAGATGAGACTAAAACAGCGATGGGAACTCGAATGCTGAGAA
CTTGGATTGACAGGCCTTTGGTAAGTATGAATCGAATCAAGGAACGTCAAGATATTATTCAAGTGTTTCTTGATTATTTT
TTTGAGAGAAATGATCTCACAGAAAGTTTAAAGGGTGTATATGATATTGAACGCCTAGCAAGTCGAGTATCTTTCGGAAA
AGCCAACCCTAAAGATCTATTGCAACTCGGACAGACCTTATCACAAATTCCTCGGATTAAAATGATTTTACAGTCCTTCA
ATCAACCTGAGCTTGACATCATTGTCAACAAAATTGACACTATGCCTGAATTAGAAAGTTTAATTAATACGGCGATAGCC
CCAGAAGCACAGGCTACTATAACTGAGGGAAACATTATCAAGTCTGGATTTGATAAGCAATTGGATAATTATCGAACAGT
GATGCGTGAAGGTACAGGTTGGATTGCTGATATTGAAGCTAAGGAAAGAGCAGCAAGTGGTATCGGTACTCTTAAAATTG
ATTATAATAAAAAAGACGGTTATTACTTCCATGTTACCAATTCCAATTTATCACTAGTACCGGAGCATTTTTTCCGTAAA
GCGACATTAAAAAATTCTGAACGCTATGGAACAGCAGAACTAGCCAAAATTGAAGGTGAAATGCTCGAAGCTCGCGAGCA
ATCTTCAAATTTAGAATATGATATTTTTATGCGTGTTCGTGCCCAAGTAGAATCTTATATTAAACGTCTTCAAGAGTTAG
CAAAGACGATTGCAACCGTTGATGTTCTACAGAGTTTGGCAGTAGTTGCAGAAAATTATCACTATGTTCGTCCAAAATTT
AATGATGAACATCAGATTAAGATTAAGAATGGGCGTCATGCAACTGTTGAAAAAGTGATGGGGGTGCAAGAATATATTCC
CAATAGTATCTATTTTGATAGTCAGACAGATATCCAGTTGATTACAGGACCAAATATGAGTGGTAAGTCGACCTATATGC
GCCAGTTAGCTTTGACAGTTATTATGGCACAAATGGGAGGTTTTGTATCGGCAGACGAAGTTGATTTGCCTGTATTTGAT
GCAATATTTACTAGGATTGGTGCTGCTGATGACTTAATTTCTGGGCAATCAACCTTTATGGTAGAAATGATGGAAGCGAA
TCAAGCTGTAAAACGAGCCAGTGATAAATCTTTGATTCTTTTTGATGAATTAGGTCGAGGGACAGCCACTTATGATGGTA
TGGCATTAGCTCAATCGATTATAGAATATATTCATAACCGTGTTAGGGCAAAAACAATGTTCGCGACTCATTACCATGAG
TTGACAGATTTATCTGAACAATTGACAAGACTTGTCAATGTACACGTGGCTACTTTAGAGAGAGATGGAGAAGTTACCTT
CTTACATAAAATTGAATCTGGACCTGCGGATAAGTCTTATGGGATACACGTCGCAAAAATAGCTGGTTTACCAATTGACT
TATTGGATAGGGCGACTGATATTTTATCACAGTTGGAAGCTGATGCAGTACAGTTGATCGTATCGCCCTCCCAAGAAGCT
GTTACTGCTGACTTAAATGAGGAACTAGATTCTGAGAAGCAACAAGGACAATTATCGCTTTTTGAAGAACCTTCAAATGC
AGGTAGGGTTATTGAGGAGTTAGAAGCGATAGATATAATGAATCTAACTCCAATGCAAGCTATGAATGCTATATTTGACT
TAAAGAAATTATTATAA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-240)

• MutS family domain IV (MutS_IV) (416-506)

• MutS domain III (MutS_III) (257-547)

• MutS domain I (MutS_I) (8-118)

• MutS domain V (MutS_V) (600-786)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	69.114	100	0.691
mutS	Pseudomonas stutzeri strain ATCC 17587	36.405	100	0.373