Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   MSA_RS10415 Genome accession   NC_021486
Coordinates   2014039..2016018 (-) Length   659 a.a.
NCBI ID   WP_079269307.1    Uniprot ID   -
Organism   Streptococcus agalactiae ILRI005     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2009039..2021018
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MSA_RS10390 (MSA_21490) recA 2009048..2010187 (-) 1140 WP_001085741.1 recombinase RecA Machinery gene
  MSA_RS10395 (MSA_21500) cinA 2010261..2011520 (-) 1260 WP_016481338.1 competence/damage-inducible protein A Machinery gene
  MSA_RS10400 (MSA_21510) - 2011609..2012160 (-) 552 WP_000817341.1 DNA-3-methyladenine glycosylase I -
  MSA_RS10405 (MSA_21520) ruvA 2012183..2012773 (-) 591 WP_000272490.1 Holliday junction branch migration protein RuvA Machinery gene
  MSA_RS10410 (MSA_21530) - 2012775..2014007 (-) 1233 WP_016481339.1 MFS transporter -
  MSA_RS10415 (MSA_21540) hexB 2014039..2016018 (-) 1980 WP_079269307.1 DNA mismatch repair endonuclease MutL Machinery gene
  MSA_RS10420 (MSA_21550) - 2016238..2016441 (+) 204 WP_000191849.1 cold shock domain-containing protein -
  MSA_RS10425 (MSA_21560) hexA 2016498..2019074 (-) 2577 WP_016481341.1 DNA mismatch repair protein MutS Machinery gene
  MSA_RS10430 (MSA_21570) argR 2019131..2019568 (-) 438 WP_001033152.1 arginine repressor -

Sequence

Protein


Download         Length: 659 a.a.        Molecular weight: 74017.21 Da        Isoelectric Point: 5.3704

>NTDB_id=49128 MSA_RS10415 WP_079269307.1 2014039..2016018(-) (hexB) [Streptococcus agalactiae ILRI005]
MNLSKIIELPDILANQIAAGEVVERPSSVVKELVENAIDAGSSQITIEVEESGLKKIQITDNGEGMTSEDAVLSLRRHAT
SKIKSQSDLFRIRTLGFRGEALPSIASISLMTIKTATEQGKQGTLLVAKGGNIEKQEVVSSPRGTKILVENLFFNTPARL
KYMKSLQSELAHIIDIVNRLSLAHPEVAFTLINDGKEMTKTSGTGDLRQAIAGIYGLNTAKKMIEISNADLDFEISGYVS
LPELTRANRNYITLLINGRYIKNFLLNRSILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKERELMSLI
STAISESLKQYDLIPDALENLAKTSTRSVDKPIQTSFSLKQPGLYYDRAKNDFFIDADTVSEPIANFTNLDKSDGSVDND
VKNSINQGATQSPSIKYASRDQADSENFIHSQDYLSSKQSLNKLVEKLDSEESSTFPELEFFGQMHGTYLFAQGNGGLYI
IDQHAAQERVKYEYYREKIGEVDNSLQQLLVPFLFEFSSSDFLQLQEKMSLLQDVGIFLEPYGNNTFILREHPIWMKEEE
VESGVYEMCDMLLLTNEVSVKKYRAELAIMMSCKRSIKANHTLDDYSARHLLDQLAQCKNPYNCPHGRPVLVNFTKADME
KMFKRIQENHTSLRDLGKY

Nucleotide


Download         Length: 1980 bp        

>NTDB_id=49128 MSA_RS10415 WP_079269307.1 2014039..2016018(-) (hexB) [Streptococcus agalactiae ILRI005]
ATGAACTTGTCTAAAATTATTGAATTACCGGATATATTAGCTAACCAGATTGCTGCTGGTGAGGTTGTTGAAAGGCCTAG
TAGCGTCGTTAAAGAATTAGTTGAAAATGCCATAGATGCAGGAAGTAGCCAAATTACCATAGAGGTTGAAGAATCTGGTC
TTAAAAAGATTCAAATAACGGATAACGGTGAAGGGATGACTAGTGAGGATGCCGTTCTCAGTTTACGACGTCACGCTACA
TCCAAAATCAAAAGCCAGAGTGACCTTTTTCGTATTCGGACCTTAGGTTTTCGTGGTGAAGCTCTACCATCAATCGCTTC
GATTAGTTTAATGACGATAAAAACAGCTACAGAGCAAGGGAAACAAGGGACGTTACTTGTTGCTAAAGGGGGAAACATTG
AAAAACAGGAAGTTGTTTCAAGTCCTCGTGGAACAAAAATTTTAGTTGAAAATTTATTCTTTAATACGCCTGCCAGATTG
AAATACATGAAGAGTTTACAGTCTGAACTAGCTCATATTATTGATATTGTTAATAGACTCAGTCTAGCGCATCCGGAAGT
TGCTTTTACACTGATAAATGATGGTAAAGAAATGACTAAAACTAGTGGGACTGGCGATTTGAGACAGGCGATTGCAGGTA
TTTATGGTTTAAATACTGCAAAAAAAATGATTGAGATTTCAAATGCAGATTTAGATTTTGAAATTTCGGGTTATGTAAGT
TTGCCTGAATTGACACGAGCTAACCGAAACTATATTACCCTATTAATTAACGGTCGTTACATTAAAAATTTTCTTTTGAA
CCGCTCAATTCTAGATGGTTATGGTTCAAAGTTGATGGTTGGAAGATTTCCAATTGCTGTCATTGATATTCAGATAGATC
CTTATCTAGCAGATGTCAACGTTCATCCGACTAAGCAAGAGGTGAGAATTTCTAAGGAACGAGAATTAATGAGTTTAATA
AGCACAGCAATTTCTGAGAGTCTTAAACAATATGATTTGATTCCGGATGCTTTAGAGAATTTAGCTAAAACTAGTACCCG
AAGTGTAGATAAGCCTATACAAACAAGCTTCTCACTAAAACAGCCTGGTTTGTATTACGATAGGGCTAAAAATGACTTTT
TTATAGATGCAGATACTGTATCTGAACCTATTGCTAACTTTACAAACCTTGACAAAAGTGACGGTTCAGTTGACAATGAT
GTAAAAAACTCTATTAATCAAGGAGCAACGCAGTCTCCTAGTATAAAGTATGCTAGTAGAGATCAAGCTGATAGTGAGAA
CTTCATTCATTCTCAGGATTACCTTAGTAGTAAACAGTCACTTAACAAACTTGTTGAAAAATTAGATTCGGAAGAAAGTT
CGACTTTTCCAGAGCTCGAATTTTTTGGTCAAATGCATGGGACCTACTTATTTGCTCAAGGGAATGGTGGGTTGTATATT
ATTGATCAACATGCAGCTCAAGAGCGTGTAAAATACGAGTATTACCGTGAAAAGATAGGTGAGGTTGATAATAGTCTTCA
ACAATTGTTAGTACCATTTCTATTTGAATTTTCAAGTTCAGATTTTCTTCAATTACAAGAAAAAATGTCATTATTACAAG
ATGTTGGTATTTTCTTGGAACCGTATGGTAATAATACTTTCATTTTAAGGGAACATCCAATTTGGATGAAAGAAGAAGAG
GTAGAGTCTGGCGTTTATGAAATGTGTGATATGTTGTTGCTCACTAATGAAGTATCAGTGAAAAAATATCGCGCAGAGTT
GGCTATTATGATGTCTTGCAAGCGATCTATTAAAGCAAACCATACGCTAGACGATTACTCAGCACGTCATTTATTAGATC
AGTTAGCGCAATGTAAAAATCCTTATAATTGCCCTCATGGAAGACCTGTTTTAGTTAATTTTACAAAAGCTGATATGGAG
AAAATGTTTAAACGAATCCAAGAAAATCATACAAGCCTCAGGGATTTAGGAAAATATTGA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(211-328)

MutL C terminal dimerisation domain (MutL_C)

(460-603)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(27-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

68.741

100

0.687