Detailed information NTG0048989

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: STH8232_RS03610
• Genome accession: NC_017581
• Coordinates: 679250..680251 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus JIM 8232
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 674250..685251

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STH8232_RS03590 (STH8232_0818)	smpB	675357..675821 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
STH8232_RS03595 (STH8232_0819)	-	675975..677381 (+)	1407	WP_011680934.1	Cof-type HAD-IIB family hydrolase	-
STH8232_RS03600 (STH8232_0820)	-	677383..677748 (+)	366	WP_014621358.1	S1 RNA-binding domain-containing protein	-
STH8232_RS03605 (STH8232_0821)	-	677851..678936 (-)	1086	WP_011225703.1	M24 family metallopeptidase	-
STH8232_RS03610 (STH8232_0822)	ccpA	679250..680251 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
STH8232_RS10395 (STH8232_0823)	-	680311..680478 (+)	168	WP_014621359.1	hypothetical protein	-
STH8232_RS03615 (STH8232_0825)	-	680614..681378 (+)	765	WP_014621361.1	MmcQ/YjbR family DNA-binding protein	-
STH8232_RS03620 (STH8232_0826)	-	681391..682506 (+)	1116	WP_041829027.1	glycerate kinase	-
STH8232_RS03625 (STH8232_0827)	-	682553..683008 (-)	456	WP_011680938.1	YueI family protein	-
STH8232_RS03630 (STH8232_0828)	eno	683217..684521 (+)	1305	WP_011680939.1	surface-displayed alpha-enolase	-
STH8232_RS03635 (STH8232_0829)	-	684675..684860 (-)	186	WP_014621363.1	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=48989 STH8232_RS03610 WP_004197422.1 679250..680251(+) (ccpA) [Streptococcus thermophilus JIM 8232]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=48989 STH8232_RS03610 WP_004197422.1 679250..680251(+) (ccpA) [Streptococcus thermophilus JIM 8232]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTCGTCATTCCAAATATTGTGAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCTGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGATGTT
ATCCTTAATCATGGTCTAACTTTACGCCAATCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547