Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   SGGB_RS05895 Genome accession   NC_017576
Coordinates   1179260..1180600 (-) Length   446 a.a.
NCBI ID   WP_009854246.1    Uniprot ID   A0A139QTN8
Organism   Streptococcus gallolyticus subsp. gallolyticus ATCC 43143     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1174260..1185600
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGGB_RS05870 (SGGB_1126) - 1174765..1175829 (-) 1065 WP_009854242.1 BMP family lipoprotein -
  SGGB_RS05875 (SGGB_1127) deoC 1176018..1176680 (-) 663 WP_009854243.1 deoxyribose-phosphate aldolase -
  SGGB_RS05880 (SGGB_1129) - 1177171..1177764 (-) 594 WP_012961986.1 class I SAM-dependent methyltransferase -
  SGGB_RS05885 (SGGB_1130) coaA 1177878..1178798 (+) 921 WP_009854245.1 type I pantothenate kinase -
  SGGB_RS05890 (SGGB_1131) rpsT 1178873..1179124 (+) 252 WP_003064878.1 30S ribosomal protein S20 -
  SGGB_RS05895 (SGGB_1132) ciaH 1179260..1180600 (-) 1341 WP_009854246.1 sensor histidine kinase Regulator
  SGGB_RS05900 (SGGB_1133) - 1180590..1181265 (-) 676 Protein_1117 response regulator transcription factor -
  SGGB_RS05905 (SGGB_1134) - 1181463..1184006 (-) 2544 WP_009854248.1 M1 family metallopeptidase -
  SGGB_RS05910 (SGGB_1135) phoU 1184229..1184882 (-) 654 WP_009854249.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50097.86 Da        Isoelectric Point: 5.3673

>NTDB_id=48916 SGGB_RS05895 WP_009854246.1 1179260..1180600(-) (ciaH) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
MLNKLQKKLSSGTFSHFFHFFAVFTGIFVIMTVIILQIMRYGLYSSVDTSLQNAADNANDYVVRTMERSDTLQSDDSSTD
TFSGGTSSSGKAKPSTGGVGLSNVSVLLYDEDGKILNALDAFVQFGTLSTTFDEDSVGEIKEQKITTIFGQTEKYHVLTV
KVSSSEYPSIKYATFLVSVRQLDEASERYVTITITVMVIFWIISVVASVYLANWTRKPIMESYEKQKSFVENASHELRTP
LAVLQNRLESLFRRPDATILDNSESIAASLDEVRNMRILTTNLLNLARRDDGLKVELEDIQPTTFNEIFENYDMIAEENG
KTFVGHNLAERPIKSDRTLLKQLMTILFDNAIKYTDDDGVIEFTVKTTDKQTILTVADNGPGISDADKVKIFDRFYRVDK
ARTRQKGGFGLGLSLAKQIVDVLKGDIQVKDNQPKGTIFEVRFNRH

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=48916 SGGB_RS05895 WP_009854246.1 1179260..1180600(-) (ciaH) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
ATGCTGAATAAATTACAGAAAAAATTATCGTCAGGGACATTTTCACATTTCTTCCATTTCTTTGCTGTCTTTACGGGAAT
TTTTGTCATCATGACAGTTATCATTTTGCAGATTATGCGCTATGGTCTTTATTCCTCTGTTGATACGAGTTTGCAAAATG
CAGCAGACAATGCCAATGATTATGTCGTGCGAACTATGGAACGTAGCGATACTTTGCAATCGGATGATTCTTCTACGGAC
ACTTTTTCAGGAGGAACAAGTAGTTCTGGGAAAGCGAAACCTAGTACTGGCGGAGTTGGTCTAAGTAACGTTAGCGTTCT
TCTTTATGATGAAGACGGTAAAATCTTAAATGCTTTGGATGCTTTTGTTCAATTTGGAACGTTATCGACAACTTTTGATG
AAGATAGTGTCGGCGAAATCAAAGAACAGAAGATTACGACCATTTTTGGTCAAACCGAGAAATACCATGTGCTGACTGTA
AAAGTGAGTAGTAGCGAGTATCCTAGTATAAAATACGCTACTTTCCTTGTTAGCGTTCGTCAGTTAGATGAAGCTAGCGA
ACGATATGTAACAATTACGATCACTGTTATGGTTATTTTCTGGATTATTTCGGTCGTAGCAAGTGTTTATCTTGCCAATT
GGACAAGAAAACCAATTATGGAAAGCTATGAAAAACAAAAATCCTTTGTCGAAAATGCTAGTCATGAGTTGCGTACACCG
CTTGCTGTTTTGCAGAATCGTTTAGAAAGTCTCTTTAGGCGACCCGATGCTACAATTTTGGATAATAGTGAAAGTATTGC
CGCCAGTCTAGACGAAGTTCGAAATATGCGAATTTTGACCACAAATCTGCTGAATTTGGCACGTCGTGACGATGGTTTGA
AAGTTGAGTTGGAGGATATTCAACCAACGACTTTCAATGAAATCTTTGAAAATTACGATATGATTGCTGAAGAAAATGGC
AAGACATTTGTCGGACATAATTTGGCAGAGCGACCAATCAAATCAGATCGTACATTGTTAAAACAACTGATGACTATCTT
ATTTGATAATGCCATAAAATACACCGACGATGATGGTGTCATTGAATTTACCGTTAAAACAACAGACAAACAAACAATTC
TGACAGTTGCTGATAACGGCCCAGGGATTAGCGACGCTGATAAAGTTAAGATTTTTGACCGTTTTTATCGTGTGGATAAA
GCACGGACACGTCAAAAAGGTGGTTTTGGTCTAGGATTGTCACTTGCTAAGCAAATTGTTGACGTTTTAAAAGGCGATAT
TCAAGTCAAAGATAACCAACCAAAAGGAACTATTTTTGAAGTTCGTTTTAATCGTCATTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(227-292)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(336-443)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A139QTN8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

59.368

99.327

0.59
  ciaH Streptococcus pneumoniae Rx1

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae D39

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae R6

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae TIGR4

51.467

99.327

0.511

Multiple sequence alignment