Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SGGB_RS02630 Genome accession   NC_017576
Coordinates   491565..492866 (+) Length   433 a.a.
NCBI ID   WP_013642741.1    Uniprot ID   -
Organism   Streptococcus gallolyticus subsp. gallolyticus ATCC 43143     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 486565..497866
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGGB_RS02605 (SGGB_0471) - 487216..487860 (+) 645 WP_009853571.1 response regulator transcription factor -
  SGGB_RS02610 (SGGB_0472) - 487979..489379 (+) 1401 WP_009853572.1 Cof-type HAD-IIB family hydrolase -
  SGGB_RS02615 (SGGB_0473) - 489379..489735 (+) 357 WP_003063541.1 S1 RNA-binding domain-containing protein -
  SGGB_RS02620 (SGGB_0474) cysK 489849..490778 (-) 930 WP_014619962.1 cysteine synthase A -
  SGGB_RS02625 (SGGB_0475) - 490882..491508 (-) 627 WP_013642740.1 YigZ family protein -
  SGGB_RS02630 (SGGB_0476) comFA/cflA 491565..492866 (+) 1302 WP_013642741.1 DEAD/DEAH box helicase Machinery gene
  SGGB_RS02635 (SGGB_0477) comFC/cflB 492863..493525 (+) 663 WP_013642742.1 ComF family protein Machinery gene
  SGGB_RS02640 (SGGB_0478) hpf 493601..494149 (+) 549 WP_013642743.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49209.45 Da        Isoelectric Point: 10.0391

>NTDB_id=48905 SGGB_RS02630 WP_013642741.1 491565..492866(+) (comFA/cflA) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
MDKLDNYYGRLFTQAQLSDALKKQAKQLPAMTKLNHHYVCNRCGSQVSLQNKLQTNVFYCRNCLVFGRNTSNGHLYYFPQ
KRFSKKDSLIWKGKLTPYQDDVSKGMLDGIDAKKDLLIHAVTGAGKTEMIYQSVSKIIDDGGCVCLASPRIDVCLELYKR
LSRDFLCPITLLHGDSEPYKRAPLIIATTHQLLKFYQAFDLLIIDEVDAFPFVDNAVLYHAVDKAIKPNGTKIFLTATST
DELDKKVKTGTLTKLHLARRFHANPLVVPQKIWLSGVLSNMQKKKIPRKLINLLKKQRQTRYPLLIFFPNIEQGEAFTQI
LQTYFPEEQIAFVSSKTENRLEIVEKFRKQELSILVTTTILERGVTFPCVDVFVVLANHRLYTKSALVQISGRVGRAAER
PTGELLFLHDGSTKEMRKAIAEIKAMNKKGGFA

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=48905 SGGB_RS02630 WP_013642741.1 491565..492866(+) (comFA/cflA) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
ATGGATAAACTGGATAATTATTATGGAAGACTATTTACACAAGCTCAACTTTCGGATGCCTTAAAAAAGCAGGCTAAACA
GTTGCCAGCAATGACAAAATTAAATCATCATTATGTTTGCAATCGTTGTGGTAGTCAAGTGTCTTTACAAAATAAACTTC
AAACAAACGTTTTTTATTGTCGAAATTGCCTTGTTTTTGGAAGAAATACGAGTAATGGACATCTCTATTATTTTCCACAA
AAACGTTTTTCTAAAAAAGATTCTCTTATTTGGAAAGGAAAATTGACTCCTTACCAAGATGACGTTTCAAAAGGGATGTT
AGACGGCATTGATGCTAAGAAAGACCTACTTATTCATGCTGTTACAGGTGCTGGAAAAACAGAAATGATTTACCAATCTG
TATCCAAAATAATTGATGACGGTGGTTGTGTTTGTCTAGCAAGTCCGCGAATTGATGTTTGTCTGGAGCTTTATAAACGC
TTGTCGCGTGATTTTTTGTGTCCGATTACATTGCTTCATGGAGATTCTGAGCCCTACAAACGTGCCCCTTTAATCATTGC
CACAACACATCAACTTTTAAAATTTTACCAAGCTTTTGATTTGTTAATTATTGATGAAGTTGATGCCTTTCCATTTGTGG
ATAATGCCGTGCTTTACCATGCTGTTGATAAAGCTATCAAACCTAATGGAACAAAGATTTTTTTAACAGCGACATCAACA
GATGAATTAGATAAAAAAGTAAAAACAGGAACTCTGACCAAATTGCACCTTGCTCGACGCTTTCATGCCAATCCATTAGT
TGTGCCACAAAAAATCTGGTTGTCTGGTGTTTTATCCAATATGCAAAAGAAGAAAATTCCCCGGAAATTAATAAATCTTC
TAAAAAAACAACGTCAAACCCGCTATCCTTTGCTAATTTTCTTCCCAAATATCGAACAAGGAGAAGCCTTTACTCAAATT
TTACAAACTTACTTTCCAGAAGAACAAATCGCTTTTGTGTCTAGTAAAACAGAAAATCGCTTAGAAATTGTAGAAAAATT
TAGGAAACAAGAACTTTCTATTTTGGTAACAACAACCATTTTAGAACGTGGTGTCACTTTCCCATGCGTAGATGTTTTTG
TAGTGCTTGCCAATCATAGATTATACACCAAAAGCGCGCTAGTTCAGATTTCAGGGCGAGTTGGGAGAGCAGCAGAGCGT
CCAACAGGAGAGCTGTTATTCTTGCATGACGGTAGTACCAAAGAAATGAGAAAAGCTATTGCTGAAATTAAAGCGATGAA
TAAAAAAGGAGGATTTGCATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(287-397)

DEAD/DEAH box helicase (DEAD)

(96-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

60.187

98.614

0.594
  comFA/cflA Streptococcus pneumoniae Rx1

60.187

98.614

0.594
  comFA/cflA Streptococcus pneumoniae D39

60.187

98.614

0.594
  comFA/cflA Streptococcus pneumoniae R6

60.187

98.614

0.594
  comFA/cflA Streptococcus pneumoniae TIGR4

60.187

98.614

0.594
  comFA/cflA Streptococcus mitis SK321

59.485

98.614

0.587
  comFA Lactococcus lactis subsp. cremoris KW2

50.98

94.226

0.48
  comFA Latilactobacillus sakei subsp. sakei 23K

38.051

99.538

0.379

Multiple sequence alignment