Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   IF745_RS13275 Genome accession   NZ_CP062338
Coordinates   2699242..2699958 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain NAS_NP_103     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2694242..2704958
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IF745_RS13255 (IF745_13200) - 2695334..2696284 (+) 951 WP_000790326.1 LacI family DNA-binding transcriptional regulator -
  IF745_RS13260 (IF745_13205) - 2696433..2697917 (+) 1485 WP_064130040.1 sucrose-6-phosphate hydrolase -
  IF745_RS13265 (IF745_13210) - 2697914..2698873 (+) 960 WP_001253302.1 carbohydrate kinase -
  IF745_RS13270 (IF745_13215) - 2699061..2699170 (-) 110 Protein_2575 hypothetical protein -
  IF745_RS13275 (IF745_13220) agrA 2699242..2699958 (-) 717 WP_000688498.1 LytTR family DNA-binding domain-containing protein Regulator
  IF745_RS13280 (IF745_13225) - 2699977..2701269 (-) 1293 WP_240024803.1 GHKL domain-containing protein -
  IF745_RS13285 (IF745_13230) - 2701294..2701434 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide -
  IF745_RS13290 (IF745_13235) agrB 2701431..2702000 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  IF745_RS13295 hld 2702290..2702370 (+) 81 WP_000046022.1 delta-hemolysin -
  IF745_RS13300 (IF745_13245) - 2702970..2703755 (-) 786 WP_000867939.1 carbon-nitrogen family hydrolase -
  IF745_RS13305 (IF745_13250) - 2704116..2704742 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=488012 IF745_RS13275 WP_000688498.1 2699242..2699958(-) (agrA) [Staphylococcus aureus strain NAS_NP_103]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=488012 IF745_RS13275 WP_000688498.1 2699242..2699958(-) (agrA) [Staphylococcus aureus strain NAS_NP_103]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996