Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   J6O57_RS03780 Genome accession   NZ_CP073718
Coordinates   758608..759267 (-) Length   219 a.a.
NCBI ID   WP_057108015.1    Uniprot ID   -
Organism   Escherichia coli strain CX08     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 753608..764267
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J6O57_RS03755 (J6O57_03715) parE 753660..755552 (+) 1893 WP_000195274.1 DNA topoisomerase IV subunit B -
  J6O57_RS03760 (J6O57_03720) ygiN 755600..755914 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  J6O57_RS03765 (J6O57_03725) mdaB 755945..756526 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  J6O57_RS03770 (J6O57_03730) ygiZ 756884..757216 (+) 333 WP_057108017.1 DUF2645 family protein -
  J6O57_RS03775 (J6O57_03735) qseC 757262..758611 (-) 1350 WP_057108016.1 quorum sensing histidine kinase QseC -
  J6O57_RS03780 (J6O57_03740) ciaR 758608..759267 (-) 660 WP_057108015.1 quorum sensing response regulator transcription factor QseB Regulator
  J6O57_RS03785 (J6O57_03745) ygiW 759419..759811 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  J6O57_RS03790 (J6O57_03750) ygiV 759864..760346 (+) 483 WP_057108014.1 GyrI-like domain-containing protein -
  J6O57_RS03795 (J6O57_03755) parC 760892..763150 (+) 2259 WP_001281881.1 DNA topoisomerase IV subunit A -
  J6O57_RS03800 (J6O57_03760) plsC 763384..764121 (+) 738 WP_000965712.1 1-acylglycerol-3-phosphate O-acyltransferase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24593.47 Da        Isoelectric Point: 6.5032

>NTDB_id=487763 J6O57_RS03780 WP_057108015.1 758608..759267(-) (ciaR) [Escherichia coli strain CX08]
MRILLIEDDMLIGDGIKTGLSKMGFSVDSFTQGRQGKEALYSAPYDAVILDLTLPGMDGHDILREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKELALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=487763 J6O57_RS03780 WP_057108015.1 758608..759267(-) (ciaR) [Escherichia coli strain CX08]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTCGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCACGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGAGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTAATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAACTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

37.885

100

0.393
  ciaR Streptococcus pneumoniae D39

37.885

100

0.393
  ciaR Streptococcus pneumoniae R6

37.885

100

0.393
  ciaR Streptococcus pneumoniae TIGR4

37.885

100

0.393
  ciaR Streptococcus mutans UA159

35.426

100

0.361