Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   J6O57_RS01835 Genome accession   NZ_CP073718
Coordinates   396478..397110 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain CX08     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 391478..402110
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J6O57_RS01810 (J6O57_01775) yhfG 391611..391778 (+) 168 WP_000736860.1 YhfG family protein -
  J6O57_RS01815 (J6O57_01780) fic 391768..392370 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  J6O57_RS01820 (J6O57_01785) pabA 392402..392965 (+) 564 WP_000601854.1 aminodeoxychorismate synthase component 2 -
  J6O57_RS01825 (J6O57_01790) argD 393051..394271 (+) 1221 WP_000963791.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  J6O57_RS01830 (J6O57_01795) yhfK 394337..396427 (-) 2091 WP_170886103.1 YccS/YhfK family membrane protein -
  J6O57_RS01835 (J6O57_01800) crp 396478..397110 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  J6O57_RS01840 (J6O57_01805) yhfA 397412..397816 (+) 405 WP_001148910.1 OsmC family protein -
  J6O57_RS01845 (J6O57_01810) prkB 397871..398740 (-) 870 WP_001274680.1 phosphoribulokinase -
  J6O57_RS01850 (J6O57_01815) yheU 398794..399012 (-) 219 WP_000907085.1 YheU family protein -
  J6O57_RS01855 (J6O57_01820) yheT 399006..400028 (-) 1023 WP_044067488.1 hydrolase -
  J6O57_RS01860 (J6O57_01825) yheS 400028..401941 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=487756 J6O57_RS01835 WP_000242755.1 396478..397110(-) (crp) [Escherichia coli strain CX08]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=487756 J6O57_RS01835 WP_000242755.1 396478..397110(-) (crp) [Escherichia coli strain CX08]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467