Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   KD735_RS03860 Genome accession   NZ_CP073624
Coordinates   798429..799088 (-) Length   219 a.a.
NCBI ID   WP_054625965.1    Uniprot ID   -
Organism   Escherichia coli strain AW1.7     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 793429..804088
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KD735_RS03830 (KD735_03790) ygiN 794330..794644 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  KD735_RS03835 (KD735_03795) mdaB 794675..795256 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  KD735_RS03840 - 795506..795985 (+) 480 WP_000065333.1 Hcp family type VI secretion system effector -
  KD735_RS03845 - 795988..796698 (+) 711 WP_000834029.1 hypothetical protein -
  KD735_RS03850 (KD735_03805) ygiZ 796705..797037 (+) 333 WP_000914691.1 DUF2645 family protein -
  KD735_RS03855 (KD735_03810) qseC 797083..798432 (-) 1350 WP_000673402.1 quorum sensing histidine kinase QseC -
  KD735_RS03860 (KD735_03815) ciaR 798429..799088 (-) 660 WP_054625965.1 quorum sensing response regulator transcription factor QseB Regulator
  KD735_RS03865 (KD735_03820) ygiW 799240..799632 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  KD735_RS03870 (KD735_03825) ygiV 799685..800167 (+) 483 WP_054625966.1 AraC family transcriptional regulator -
  KD735_RS03875 (KD735_03830) mqsR 800372..800668 (+) 297 WP_000415584.1 type II toxin-antitoxin system toxin MqsR -
  KD735_RS03880 (KD735_03835) mqsA 800670..801065 (+) 396 WP_000650107.1 type II toxin-antitoxin system antitoxin MqsA -
  KD735_RS03885 (KD735_03840) ygiS 801198..802805 (+) 1608 WP_001295629.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24701.65 Da        Isoelectric Point: 6.9850

>NTDB_id=487491 KD735_RS03860 WP_054625965.1 798429..799088(-) (ciaR) [Escherichia coli strain AW1.7]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERIEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=487491 KD735_RS03860 WP_054625965.1 798429..799088(-) (ciaR) [Escherichia coli strain AW1.7]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTATAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365