Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   KDN44_RS03440 Genome accession   NZ_CP073360
Coordinates   707390..708049 (-) Length   219 a.a.
NCBI ID   WP_001221502.1    Uniprot ID   B7LGG8
Organism   Escherichia coli strain EC11     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 702390..713049
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KDN44_RS03415 parE 702481..704373 (+) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -
  KDN44_RS03420 ygiN 704421..704735 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  KDN44_RS03425 mdaB 704766..705347 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  KDN44_RS03430 ygiZ 705666..705998 (+) 333 WP_000912120.1 DUF2645 family protein -
  KDN44_RS03435 qseC 706044..707393 (-) 1350 WP_000673354.1 quorum sensing histidine kinase QseC -
  KDN44_RS03440 ciaR 707390..708049 (-) 660 WP_001221502.1 quorum sensing response regulator transcription factor QseB Regulator
  KDN44_RS03445 ygiW 708201..708593 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  KDN44_RS03450 ygiV 708646..709128 (+) 483 WP_000183494.1 GyrI-like domain-containing protein -
  KDN44_RS03455 parC 709674..711932 (+) 2259 WP_001281841.1 DNA topoisomerase IV subunit A -
  KDN44_RS03460 plsC 712166..712903 (+) 738 WP_000965712.1 1-acylglycerol-3-phosphate O-acyltransferase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24745.66 Da        Isoelectric Point: 6.6543

>NTDB_id=487245 KDN44_RS03440 WP_001221502.1 707390..708049(-) (ciaR) [Escherichia coli strain EC11]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=487245 KDN44_RS03440 WP_001221502.1 707390..708049(-) (ciaR) [Escherichia coli strain EC11]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCGCCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGAGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B7LGG8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365