Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   KCG52_RS07570 Genome accession   NZ_CP073114
Coordinates   1582505..1583182 (-) Length   225 a.a.
NCBI ID   WP_254343588.1    Uniprot ID   -
Organism   Neisseria subflava strain HP0048     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1577505..1588182
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KCG52_RS07555 (KCG52_07535) - 1579419..1579931 (+) 513 WP_283254529.1 shikimate kinase -
  KCG52_RS07560 (KCG52_07540) aroB 1579953..1581032 (+) 1080 WP_107848890.1 3-dehydroquinate synthase -
  KCG52_RS07565 (KCG52_07545) - 1581162..1582475 (-) 1314 WP_254343586.1 ATP-binding protein -
  KCG52_RS07570 (KCG52_07550) ciaR 1582505..1583182 (-) 678 WP_254343588.1 response regulator Regulator
  KCG52_RS07575 (KCG52_07555) - 1583328..1583894 (-) 567 WP_049328898.1 NADPH-dependent FMN reductase -
  KCG52_RS07580 (KCG52_07560) - 1584031..1585458 (+) 1428 WP_254343589.1 MFS transporter -
  KCG52_RS07585 (KCG52_07565) dacB 1585529..1586941 (+) 1413 WP_254343590.1 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 24333.92 Da        Isoelectric Point: 4.8995

>NTDB_id=486812 KCG52_RS07570 WP_254343588.1 1582505..1583182(-) (ciaR) [Neisseria subflava strain HP0048]
MRVLLVEDDAMIAQAVSANLKDTGYAVDWVSRGSEVAAAVAAQAYDLLLLDLGLPGKDGLDVLAQIRNGGCTVPVLIVTA
RDDLHSRLNGLDGGADDYIVKPFDMAELQARMRAVLRRHGGQVQTLLTNGIITLNPSTHQAEVVGQEQAVMLSNKEFAVL
QALLLRPGMILSRSDLEDKIYGWGEEVESNAVDFLIHALRKKLGKEAIQNVRGVGWLVAQNNQAV

Nucleotide


Download         Length: 678 bp        

>NTDB_id=486812 KCG52_RS07570 WP_254343588.1 1582505..1583182(-) (ciaR) [Neisseria subflava strain HP0048]
ATGCGCGTATTATTGGTTGAAGACGATGCCATGATTGCCCAAGCCGTCAGTGCCAACCTGAAAGACACCGGCTACGCTGT
CGATTGGGTCAGCCGCGGTTCGGAAGTGGCCGCGGCAGTGGCGGCGCAGGCATACGATTTGCTGCTCTTGGATTTGGGTT
TGCCCGGCAAAGACGGTTTGGACGTATTGGCGCAAATCCGCAACGGCGGCTGTACCGTTCCCGTCTTAATCGTAACCGCG
CGCGATGATTTGCACAGCCGCCTCAACGGCCTGGACGGCGGCGCAGACGACTACATCGTCAAACCCTTCGACATGGCGGA
ACTGCAAGCCCGTATGCGCGCCGTATTGCGCCGACACGGCGGACAGGTGCAAACGCTGCTGACCAACGGCATCATCACGC
TCAACCCTTCCACCCATCAGGCGGAAGTAGTCGGGCAGGAACAGGCCGTCATGCTCAGCAACAAAGAATTTGCCGTCCTC
CAAGCCCTGCTGCTGCGTCCGGGCATGATTCTGTCGCGCAGCGATTTGGAAGACAAAATCTACGGCTGGGGCGAAGAAGT
CGAAAGCAACGCCGTTGACTTCCTGATTCACGCCTTACGCAAAAAACTCGGCAAAGAAGCGATTCAAAACGTCCGCGGGG
TCGGCTGGCTGGTTGCACAAAACAACCAGGCCGTCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(148-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

37.004

100

0.373
  ciaR Streptococcus pneumoniae Rx1

36.937

98.667

0.364
  ciaR Streptococcus pneumoniae D39

36.937

98.667

0.364
  ciaR Streptococcus pneumoniae R6

36.937

98.667

0.364
  ciaR Streptococcus pneumoniae TIGR4

36.937

98.667

0.364