Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   I872_RS09950 Genome accession   NC_021175
Coordinates   2014761..2016707 (-) Length   648 a.a.
NCBI ID   WP_015605960.1    Uniprot ID   A0ABM5NMF3
Organism   Streptococcus cristatus AS 1.3089     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2009761..2021707
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I872_RS09915 (I872_09940) - 2010492..2010902 (+) 411 WP_041826926.1 helix-turn-helix domain-containing protein -
  I872_RS09920 (I872_09945) - 2010946..2011503 (-) 558 WP_015605954.1 GNAT family N-acetyltransferase -
  I872_RS09925 (I872_09950) - 2011575..2012234 (-) 660 WP_015605955.1 type II CAAX prenyl endopeptidase Rce1 family protein -
  I872_RS09930 (I872_09955) - 2012239..2012793 (-) 555 WP_015605956.1 DNA-3-methyladenine glycosylase I -
  I872_RS09935 (I872_09960) ruvA 2012803..2013393 (-) 591 WP_015605957.1 Holliday junction branch migration protein RuvA Machinery gene
  I872_RS09940 (I872_09965) - 2013563..2014069 (+) 507 WP_015605958.1 helix-turn-helix domain-containing protein -
  I872_RS09945 (I872_09970) - 2014053..2014628 (+) 576 WP_015605959.1 RDD family protein -
  I872_RS09950 (I872_09975) hexB 2014761..2016707 (-) 1947 WP_015605960.1 DNA mismatch repair endonuclease MutL Machinery gene
  I872_RS09955 (I872_09980) brsR 2016892..2017332 (+) 441 WP_015605961.1 LytTR family DNA-binding domain-containing protein Regulator
  I872_RS09960 (I872_09985) - 2017329..2017799 (+) 471 WP_015605962.1 DUF3021 family protein -
  I872_RS09965 (I872_09990) hexA 2017995..2020544 (-) 2550 WP_015605963.1 DNA mismatch repair protein MutS Machinery gene
  I872_RS09970 (I872_09995) argR 2020617..2021057 (-) 441 WP_015605964.1 arginine repressor -

Sequence

Protein


Download         Length: 648 a.a.        Molecular weight: 73408.47 Da        Isoelectric Point: 5.1215

>NTDB_id=48582 I872_RS09950 WP_015605960.1 2014761..2016707(-) (hexB) [Streptococcus cristatus AS 1.3089]
MSKIIELPEILANQIAAGEVIERPSSVVKELVENSIDAGASQITIEIEEAGLKSIQVTDNGEGIDHQDVPLALRRHATSK
IKKQADLFRIRTLGFRGEAIPSIASVSRFTIETATESGQHGTLLVAQGGEIEEHEPTSSPVGTKIKIEDLFFNTPARLKY
MKSQQAELSHIVDVINRLSLAHPEVAFTLISDGREMTRTAGSGNLRQAIAGIYGLATAKKMVEISASDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPLAVINIQIDPYLADVNVHPTKQEVRISKERELMTLISQ
AIATSLKEQDLIPDALENLAKSTVKRATKPEQTSLPLKENRLYYDREQNDFFLKPQVAEQQLFFEESAEPVHEATDEKAE
LPQSTSVKFAERKPASHDQLDHPELDQASLERAVDKLEQEEKSSFPELEYFGQMHGTYLFAQGKGGLYIIDQHAAQERVK
YEYYREKIGDVDNSQQQLLVPHIFEFPADDMLRIKQRMELLEDAGIFLEEYGANQFILREHPIWFKEEEIEAGIYEMCDM
LLLTKEVSIKKYRAELAIMMSCKRSIKANHSLDDYSARDLLFQLSQCDNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHT
SLRELGKY

Nucleotide


Download         Length: 1947 bp        

>NTDB_id=48582 I872_RS09950 WP_015605960.1 2014761..2016707(-) (hexB) [Streptococcus cristatus AS 1.3089]
ATGTCAAAAATTATCGAACTTCCAGAAATTCTAGCCAATCAGATTGCGGCCGGTGAAGTCATTGAACGGCCTAGCAGCGT
GGTCAAGGAGCTAGTGGAGAACTCAATTGATGCGGGTGCCAGTCAGATTACGATCGAAATCGAAGAAGCTGGACTCAAGA
GCATTCAGGTGACGGATAATGGCGAGGGCATTGACCACCAAGATGTCCCTCTGGCCCTTCGACGCCATGCTACCAGTAAA
ATCAAGAAGCAAGCGGATCTCTTTCGGATTCGGACGCTGGGTTTTCGTGGTGAGGCCATTCCTTCCATTGCTTCTGTCTC
ACGTTTTACCATTGAAACAGCGACTGAATCTGGCCAGCATGGGACTCTACTAGTTGCCCAAGGCGGTGAGATTGAAGAGC
ATGAGCCGACCAGCAGTCCGGTAGGAACGAAAATCAAGATAGAAGATCTCTTCTTCAATACTCCAGCCCGGCTCAAGTAT
ATGAAGAGCCAGCAGGCTGAGCTGTCCCATATTGTTGATGTGATTAATCGGCTTAGTCTGGCCCATCCGGAAGTGGCTTT
CACCCTTATCAGTGACGGCCGCGAAATGACACGGACTGCCGGCAGTGGCAATCTGCGTCAGGCTATTGCGGGTATCTATG
GTCTGGCAACAGCCAAGAAAATGGTGGAAATCTCTGCTTCAGATCTGGATTTTGAAGTGAGCGGCTATGTCAGTCTGCCT
GAGCTGACTCGGGCAAATCGTAATTATATTACGATTCTCATCAACGGCCGTTATATCAAGAATTTCCTGCTCAATCGTGC
TATTTTGGATGGCTACGGCAGCAAGCTTATGGTAGGCCGCTTTCCACTAGCGGTCATCAATATTCAGATTGACCCCTATC
TGGCCGATGTCAATGTCCATCCGACCAAGCAAGAGGTGCGGATTTCTAAAGAGCGGGAACTCATGACCTTGATTTCACAA
GCCATTGCGACTAGTCTCAAGGAGCAAGACCTGATTCCGGATGCTTTGGAAAATCTAGCCAAATCAACTGTTAAGCGTGC
GACTAAGCCCGAACAGACCAGTCTTCCGCTGAAAGAAAATCGCCTCTACTACGATAGGGAGCAGAATGATTTCTTCCTCA
AGCCGCAGGTGGCTGAGCAGCAGCTATTCTTTGAAGAATCAGCGGAGCCTGTCCATGAAGCGACAGATGAAAAAGCAGAA
CTGCCACAATCGACTTCGGTCAAATTTGCAGAGAGAAAGCCTGCCAGCCATGACCAACTAGACCATCCAGAGCTAGATCA
GGCTAGTCTGGAGCGGGCTGTGGATAAGTTGGAACAAGAAGAGAAGTCAAGCTTCCCAGAGTTAGAATATTTCGGCCAGA
TGCATGGTACCTATCTCTTTGCTCAGGGCAAGGGCGGTCTTTACATTATTGACCAACATGCCGCCCAAGAGCGAGTCAAG
TATGAGTATTATCGGGAGAAGATTGGGGATGTGGACAATAGCCAGCAGCAGCTCTTAGTACCTCATATCTTTGAATTTCC
AGCGGATGATATGTTGCGAATCAAGCAGCGGATGGAGTTGTTAGAAGATGCTGGCATCTTTTTAGAAGAGTACGGAGCCA
ATCAGTTTATCCTCCGCGAGCATCCCATTTGGTTCAAGGAAGAGGAGATTGAAGCCGGCATCTATGAAATGTGTGATATG
CTTCTCCTGACCAAGGAAGTTTCCATCAAGAAATATCGGGCAGAGCTGGCCATTATGATGAGCTGCAAACGCTCCATCAA
GGCCAATCACAGTCTGGATGACTACTCTGCGCGTGACTTGCTCTTTCAGCTGTCCCAGTGTGACAATCCCTATAACTGCC
CACACGGCCGGCCGGTCTTGGTCAACTTTACCAAGTCGGATATGGAAAAAATGTTCCGCCGTATTCAGGAAAATCACACT
AGCCTGCGGGAGTTAGGGAAATACTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-117)

MutL C terminal dimerisation domain (MutL_C)

(450-592)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

77.812

100

0.779

Multiple sequence alignment