Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   J7U23_RS03715 Genome accession   NZ_CP072435
Coordinates   698665..699405 (+) Length   246 a.a.
NCBI ID   WP_096811959.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain S24736     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 693665..704405
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7U23_RS03695 (J7U23_03670) - 695195..695557 (+) 363 WP_039671040.1 SAG1252 family conjugative relaxosome accessory protein -
  J7U23_RS03700 (J7U23_03675) mobC 695560..695925 (+) 366 WP_039671039.1 plasmid mobilization relaxosome protein MobC -
  J7U23_RS03705 (J7U23_03680) - 695912..697795 (+) 1884 WP_111679172.1 SAG1250 family conjugative relaxase -
  J7U23_RS03710 (J7U23_03685) - 698322..698663 (+) 342 WP_024404826.1 LytTR family DNA-binding domain-containing protein -
  J7U23_RS03715 (J7U23_03690) comE/blpR 698665..699405 (+) 741 WP_096811959.1 response regulator transcription factor Regulator
  J7U23_RS03720 (J7U23_03695) - 699416..700756 (+) 1341 WP_039671036.1 sensor histidine kinase -
  J7U23_RS03725 (J7U23_03700) - 700804..700959 (-) 156 WP_096811960.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  J7U23_RS03730 (J7U23_03705) comB 701058..702419 (-) 1362 WP_096811961.1 bacteriocin secretion accessory protein Regulator

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28894.15 Da        Isoelectric Point: 7.2201

>NTDB_id=482767 J7U23_RS03715 WP_096811959.1 698665..699405(+) (comE/blpR) [Streptococcus thermophilus strain S24736]
MNIFVMEDDFMQQARIEKIITKLLEKHNIVPKKFEISGKPHQLLQAIEEKGVHQLFFLDIEIKEDELKGLQVAKQIREID
PYASIVFVTTHSEFMPLSFRYQVSALDYIDKELGVTEFESRIEAALLHTHNKDNSAVSDDSFYFKSKYAQVQYPFNEVYY
IETSPRPHRVILYTKTDRMEFTASLSDILKQDKRLVQCHRSFAINPRNVVKVDRNEKQIYFPNGATCFISRQKLESTLAV
IDRLHR

Nucleotide


Download         Length: 741 bp        

>NTDB_id=482767 J7U23_RS03715 WP_096811959.1 698665..699405(+) (comE/blpR) [Streptococcus thermophilus strain S24736]
ATGAATATCTTTGTAATGGAAGATGATTTTATGCAACAAGCGAGAATTGAGAAGATTATTACTAAGCTGTTAGAAAAGCA
CAACATCGTTCCGAAAAAATTTGAAATTTCAGGAAAACCTCATCAGCTACTTCAAGCAATAGAAGAAAAAGGAGTACATC
AGCTCTTCTTTTTAGATATTGAGATTAAGGAAGACGAACTAAAAGGACTTCAAGTCGCTAAACAAATTAGAGAGATTGAC
CCTTATGCTAGTATTGTTTTTGTGACAACACACTCCGAGTTTATGCCCTTATCTTTCAGGTACCAGGTATCTGCCTTGGA
CTATATTGACAAAGAGCTTGGAGTTACCGAATTTGAATCGCGAATAGAAGCAGCTTTACTTCATACTCACAATAAGGACA
ATAGCGCCGTATCGGATGATTCATTCTATTTTAAGTCCAAATATGCTCAAGTACAATACCCATTCAATGAAGTGTACTAC
ATCGAGACTTCTCCCCGCCCTCATCGTGTTATCCTTTATACCAAGACAGACCGAATGGAGTTCACAGCAAGTTTGTCAGA
CATTTTGAAACAAGATAAACGACTTGTACAATGTCATCGTTCGTTTGCAATCAATCCGAGGAATGTTGTTAAAGTGGATA
GAAATGAAAAACAGATCTACTTTCCTAATGGAGCCACCTGTTTTATTTCAAGGCAAAAGCTAGAATCAACTTTAGCTGTT
ATTGATAGACTGCATAGATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.719

98.374

0.528
  comE/comE1 Streptococcus equinus JB1

41.423

97.154

0.402
  comE/comE2 Streptococcus equinus JB1

36.475

99.187

0.362