Detailed information NTG0481424

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: D39N_RS09000
• Genome accession: NZ_CP061208
• Coordinates: 1791274..1792284 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990602.1
• Uniprot ID: A0A0H2ZQ65
• Organism: Streptococcus pneumoniae strain D39_P0
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1786274..1797284

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D39N_RS08970 (D39N_01801)	-	1786294..1787508 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
D39N_RS08975 (D39N_01802)	-	1787664..1787957 (-)	294	WP_000977365.1	hypothetical protein	-
D39N_RS08980 (D39N_01803)	-	1788119..1788571 (+)	453	WP_000079154.1	universal stress protein	-
D39N_RS08985 (D39N_01804)	-	1788606..1789994 (-)	1389	WP_000453139.1	Cof-type HAD-IIB family hydrolase	-
D39N_RS08990 (D39N_01805)	-	1790060..1791022 (+)	963	WP_001124777.1	asparaginase	-
D39N_RS08995	-	1791019..1791210 (-)	192	WP_001092029.1	hypothetical protein	-
D39N_RS09000 (D39N_01806)	ccpA	1791274..1792284 (-)	1011	WP_000990602.1	catabolite control protein A	Regulator
D39N_RS09005 (D39N_01807)	-	1792709..1793308 (-)	600	WP_000866719.1	response regulator transcription factor	-
D39N_RS09010 (D39N_01808)	-	1793310..1794407 (-)	1098	WP_000893546.1	sensor histidine kinase	-
D39N_RS09015 (D39N_01809)	-	1794407..1795144 (-)	738	WP_000832834.1	ABC transporter permease	-
D39N_RS09020 (D39N_01810)	-	1795146..1796030 (-)	885	WP_000219348.1	ABC transporter ATP-binding protein	-
D39N_RS09025 (D39N_01811)	-	1796017..1796211 (-)	195	WP_000820180.1	hypothetical protein	-
D39N_RS09030 (D39N_01812)	-	1796208..1796414 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37042.99 Da
• Isoelectric Point: 5.3212

>NTDB_id=481424 D39N_RS09000 WP_000990602.1 1791274..1792284(-) (ccpA) [Streptococcus pneumoniae strain D39_P0]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTATVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=481424 D39N_RS09000 WP_000990602.1 1791274..1792284(-) (ccpA) [Streptococcus pneumoniae strain D39_P0]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAGCCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCTATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0H2ZQ65

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	100	100	1
ccpA	Streptococcus gordonii str. Challis substr. CH1	86.826	99.405	0.863
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.402	98.512	0.565