Detailed information NTG0480978

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: IB935_RS02290
• Genome accession: NZ_CP061134
• Coordinates: 428210..429211 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain BSAC_bs192 isolate Invasive disease
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 423210..434211

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IB935_RS02265 (IB935_02265)	-	423884..424567 (-)	684	WP_011017476.1	DUF969 domain-containing protein	-
IB935_RS02270 (IB935_02270)	-	424778..425704 (-)	927	WP_002990711.1	glycosyltransferase family 2 protein	-
IB935_RS02275 (IB935_02275)	-	425849..426226 (-)	378	WP_002985686.1	VOC family protein	-
IB935_RS02280 (IB935_02280)	-	426237..426902 (-)	666	WP_121158073.1	NAD(P)H-dependent oxidoreductase	-
IB935_RS02285 (IB935_02285)	-	426951..428036 (-)	1086	WP_011528361.1	aminopeptidase P family protein	-
IB935_RS02290 (IB935_02290)	ccpA	428210..429211 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
IB935_RS02295 (IB935_02295)	-	429342..430340 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
IB935_RS02300 (IB935_02300)	-	430342..431676 (+)	1335	WP_011528362.1	glycosyltransferase family 4 protein	-
IB935_RS02305 (IB935_02305)	thrS	432098..434041 (+)	1944	WP_011528363.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=480978 IB935_RS02290 WP_002985680.1 428210..429211(+) (ccpA) [Streptococcus pyogenes strain BSAC_bs192 isolate Invasive disease]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=480978 IB935_RS02290 WP_002985680.1 428210..429211(+) (ccpA) [Streptococcus pyogenes strain BSAC_bs192 isolate Invasive disease]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559