Detailed information NTG0048091

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: SPN994038_RS09500
• Genome accession: NC_021026
• Coordinates: 1764379..1765278 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904867.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae SPN994038
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1759379..1770278

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPN994038_RS09475 (SPN994038_17360)	rsmA	1759709..1760581 (-)	873	WP_001216830.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
SPN994038_RS09480 (SPN994038_17370)	-	1760712..1761020 (-)	309	WP_000333257.1	hypothetical protein	-
SPN994038_RS09485 (SPN994038_17380)	-	1761013..1761654 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
SPN994038_RS09490 (SPN994038_17390)	-	1761656..1763686 (-)	2031	WP_000825263.1	bacteriocin-associated integral membrane family protein	-
SPN994038_RS09495 (SPN994038_17400)	-	1763763..1764059 (-)	297	WP_000815394.1	lactococcin 972 family bacteriocin	-
SPN994038_RS09500 (SPN994038_17410)	comR	1764379..1765278 (-)	900	WP_000904867.1	helix-turn-helix domain-containing protein	Regulator
SPN994038_RS09505 (SPN994038_17420)	rnmV	1765350..1765910 (-)	561	WP_000664448.1	ribonuclease M5	-
SPN994038_RS09510 (SPN994038_17430)	-	1765910..1766683 (-)	774	WP_000575607.1	TatD family hydrolase	-
SPN994038_RS09515 (SPN994038_17440)	-	1766989..1767696 (-)	708	Protein_1815	DUF1542 domain-containing protein	-
SPN994038_RS09520 (SPN994038_17450)	rpmH	1767905..1768039 (-)	135	WP_000831906.1	50S ribosomal protein L34	-
SPN994038_RS09525 (SPN994038_17460)	-	1768184..1769398 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
SPN994038_RS09530 (SPN994038_17470)	-	1769554..1769847 (-)	294	WP_000977365.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35191.04 Da
• Isoelectric Point: 5.0703

>NTDB_id=48091 SPN994038_RS09500 WP_000904867.1 1764379..1765278(-) (comR) [Streptococcus pneumoniae SPN994038]
MLIGQKIKEIRIEKGISRPDFCGDEQGLTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=48091 SPN994038_RS09500 WP_000904867.1 1764379..1765278(-) (comR) [Streptococcus pneumoniae SPN994038]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGG
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAGAAGGTAACTCAAATAGAGAATTACTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCTTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (7-59)

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	37.801	97.324	0.368
comR	Streptococcus suis 05ZYH33	37.801	97.324	0.368