Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilV   Type   Machinery gene
Locus tag   NMBH4476_RS07250 Genome accession   NC_017516
Coordinates   1390661..1391281 (-) Length   206 a.a.
NCBI ID   WP_002225360.1    Uniprot ID   -
Organism   Neisseria meningitidis H44/76     
Function   repress natural transformation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1375355..1391973 1390661..1391281 within 0


Gene organization within MGE regions


Location: 1375355..1391973
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMBH4476_RS07120 (NMBH4476_1262) - 1375454..1375879 (+) 426 WP_002219430.1 hypothetical protein -
  NMBH4476_RS07125 (NMBH4476_1263) - 1376123..1376323 (+) 201 WP_002219431.1 hypothetical protein -
  NMBH4476_RS07130 (NMBH4476_1264) - 1376391..1376750 (+) 360 WP_002219432.1 hypothetical protein -
  NMBH4476_RS07135 (NMBH4476_1265) - 1376775..1377629 (+) 855 WP_002219433.1 YfdQ family protein -
  NMBH4476_RS07140 (NMBH4476_1266) - 1377699..1377914 (+) 216 WP_002219434.1 hypothetical protein -
  NMBH4476_RS07145 (NMBH4476_1267) - 1377949..1378209 (+) 261 WP_002223443.1 NGO1622 family putative holin -
  NMBH4476_RS07150 (NMBH4476_1268) - 1378206..1378499 (+) 294 WP_002220689.1 hypothetical protein -
  NMBH4476_RS07155 (NMBH4476_1269) - 1378502..1378693 (+) 192 WP_002219435.1 type ISP restriction/modification enzyme -
  NMBH4476_RS07160 (NMBH4476_1270) - 1378693..1378833 (+) 141 WP_002225349.1 hypothetical protein -
  NMBH4476_RS07165 (NMBH4476_1271) - 1378830..1379039 (+) 210 WP_002220687.1 hypothetical protein -
  NMBH4476_RS07170 (NMBH4476_1272) - 1379097..1380014 (-) 918 WP_002219437.1 KilA-N domain-containing protein -
  NMBH4476_RS07175 (NMBH4476_1273) - 1380883..1381239 (-) 357 WP_002223441.1 DUF4760 domain-containing protein -
  NMBH4476_RS07190 (NMBH4476_1275) - 1381787..1382167 (-) 381 WP_002220683.1 type II toxin-antitoxin system PemK/MazF family toxin -
  NMBH4476_RS07195 (NMBH4476_1276) - 1382280..1383352 (-) 1073 Protein_1322 tyrosine-type recombinase/integrase -
  NMBH4476_RS07210 (NMBH4476_1279) yaaA 1383881..1384660 (-) 780 WP_002225351.1 peroxide stress protein YaaA -
  NMBH4476_RS15850 - 1384709..1384834 (-) 126 Protein_1324 IS5/IS1182 family transposase -
  NMBH4476_RS07215 (NMBH4476_1280) dapC 1384923..1386110 (-) 1188 WP_002225352.1 succinyldiaminopimelate transaminase -
  NMBH4476_RS07220 (NMBH4476_1281) dut 1386188..1386640 (-) 453 WP_002225353.1 dUTP diphosphatase -
  NMBH4476_RS07225 (NMBH4476_1282) - 1386840..1387208 (+) 369 Protein_1327 AzlC family ABC transporter permease -
  NMBH4476_RS07235 (NMBH4476_1283) pilX 1388673..1389146 (-) 474 WP_002225356.1 PilX family type IV pilin Machinery gene
  NMBH4476_RS07240 (NMBH4476_1284) pilK 1389151..1389744 (-) 594 WP_002244085.1 PilX N-terminal domain-containing pilus assembly protein Machinery gene
  NMBH4476_RS07245 (NMBH4476_1285) pilJ 1389723..1390664 (-) 942 WP_033911581.1 PilW family protein Machinery gene
  NMBH4476_RS07250 (NMBH4476_1286) pilV 1390661..1391281 (-) 621 WP_002225360.1 type IV pilus modification protein PilV Machinery gene
  NMBH4476_RS07255 (NMBH4476_1287) pilH 1391305..1391973 (-) 669 WP_002230433.1 Tfp pilus assembly protein FimT/FimU Machinery gene

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 22325.27 Da        Isoelectric Point: 4.9868

>NTDB_id=48058 NMBH4476_RS07250 WP_002225360.1 1390661..1391281(-) (pilV) [Neisseria meningitidis H44/76]
MKNNDCFRLKDSQSGMALIEVLVAMLVLTIGILALLSVQLRTVASVREAETQTIVSQITQNLMEGMLMNPTIDSDSNKKN
YNLYMGNHTLPHTLSAVDGDFAIDAMKTKGQLAEAQLKRFSYELKNALPDAAAIHYAVCKDSSGNAPTLSGNAFSSNCDN
KANGDTLIKVLWVNDSAGDSDISRTNLEVSGDNIVYTYQARVGGRE

Nucleotide


Download         Length: 621 bp        

>NTDB_id=48058 NMBH4476_RS07250 WP_002225360.1 1390661..1391281(-) (pilV) [Neisseria meningitidis H44/76]
ATGAAGAATAATGATTGCTTCCGCCTGAAAGATTCCCAGTCCGGTATGGCGCTGATAGAAGTCTTGGTTGCTATGCTCGT
TCTGACCATCGGTATTTTGGCACTATTGTCTGTACAGTTGCGGACAGTCGCTTCCGTCAGGGAGGCGGAGACACAAACCA
TCGTCAGCCAAATCACGCAAAACCTGATGGAGGGAATGTTGATGAATCCGACCATTGATTCGGACAGCAACAAGAAAAAC
TATAATCTTTACATGGGAAACCATACACTACCGCATACACTATCAGCTGTGGATGGCGATTTTGCGATTGATGCCATGAA
AACTAAGGGGCAATTGGCAGAGGCACAATTGAAGAGATTTAGTTATGAGCTGAAAAATGCCTTGCCGGATGCGGCAGCCA
TCCATTACGCCGTCTGCAAGGATTCGTCGGGTAACGCGCCGACATTGTCCGGCAATGCTTTTTCTTCAAATTGCGACAAT
AAGGCAAACGGGGATACTTTAATTAAAGTATTGTGGGTAAATGATTCGGCAGGGGATTCGGATATTTCCCGTACGAATCT
TGAGGTGAGCGGCGACAATATCGTATATACTTATCAGGCAAGGGTCGGAGGTCGGGAATGA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-36)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilV Neisseria meningitidis 8013

98.544

100

0.985
  pilI Neisseria gonorrhoeae MS11

83.01

100

0.83
  pilV Neisseria gonorrhoeae MS11

83.01

100

0.83

Multiple sequence alignment