Detailed information
Bioinformatically predicted
Overview
| Name | pilX | Type | Machinery gene |
| Locus tag | NMBH4476_RS07235 | Genome accession | NC_017516 |
| Coordinates | 1388673..1389146 (-) | Length | 157 a.a. |
| NCBI ID | WP_002225356.1 | Uniprot ID | - |
| Organism | Neisseria meningitidis H44/76 | ||
| Function | assembly of type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 1375355..1391973 | 1388673..1389146 | within | 0 |
Gene organization within MGE regions
Location: 1375355..1391973
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NMBH4476_RS07120 (NMBH4476_1262) | - | 1375454..1375879 (+) | 426 | WP_002219430.1 | hypothetical protein | - |
| NMBH4476_RS07125 (NMBH4476_1263) | - | 1376123..1376323 (+) | 201 | WP_002219431.1 | hypothetical protein | - |
| NMBH4476_RS07130 (NMBH4476_1264) | - | 1376391..1376750 (+) | 360 | WP_002219432.1 | hypothetical protein | - |
| NMBH4476_RS07135 (NMBH4476_1265) | - | 1376775..1377629 (+) | 855 | WP_002219433.1 | YfdQ family protein | - |
| NMBH4476_RS07140 (NMBH4476_1266) | - | 1377699..1377914 (+) | 216 | WP_002219434.1 | hypothetical protein | - |
| NMBH4476_RS07145 (NMBH4476_1267) | - | 1377949..1378209 (+) | 261 | WP_002223443.1 | NGO1622 family putative holin | - |
| NMBH4476_RS07150 (NMBH4476_1268) | - | 1378206..1378499 (+) | 294 | WP_002220689.1 | hypothetical protein | - |
| NMBH4476_RS07155 (NMBH4476_1269) | - | 1378502..1378693 (+) | 192 | WP_002219435.1 | type ISP restriction/modification enzyme | - |
| NMBH4476_RS07160 (NMBH4476_1270) | - | 1378693..1378833 (+) | 141 | WP_002225349.1 | hypothetical protein | - |
| NMBH4476_RS07165 (NMBH4476_1271) | - | 1378830..1379039 (+) | 210 | WP_002220687.1 | hypothetical protein | - |
| NMBH4476_RS07170 (NMBH4476_1272) | - | 1379097..1380014 (-) | 918 | WP_002219437.1 | KilA-N domain-containing protein | - |
| NMBH4476_RS07175 (NMBH4476_1273) | - | 1380883..1381239 (-) | 357 | WP_002223441.1 | DUF4760 domain-containing protein | - |
| NMBH4476_RS07190 (NMBH4476_1275) | - | 1381787..1382167 (-) | 381 | WP_002220683.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| NMBH4476_RS07195 (NMBH4476_1276) | - | 1382280..1383352 (-) | 1073 | Protein_1322 | tyrosine-type recombinase/integrase | - |
| NMBH4476_RS07210 (NMBH4476_1279) | yaaA | 1383881..1384660 (-) | 780 | WP_002225351.1 | peroxide stress protein YaaA | - |
| NMBH4476_RS15850 | - | 1384709..1384834 (-) | 126 | Protein_1324 | IS5/IS1182 family transposase | - |
| NMBH4476_RS07215 (NMBH4476_1280) | dapC | 1384923..1386110 (-) | 1188 | WP_002225352.1 | succinyldiaminopimelate transaminase | - |
| NMBH4476_RS07220 (NMBH4476_1281) | dut | 1386188..1386640 (-) | 453 | WP_002225353.1 | dUTP diphosphatase | - |
| NMBH4476_RS07225 (NMBH4476_1282) | - | 1386840..1387208 (+) | 369 | Protein_1327 | AzlC family ABC transporter permease | - |
| NMBH4476_RS07235 (NMBH4476_1283) | pilX | 1388673..1389146 (-) | 474 | WP_002225356.1 | PilX family type IV pilin | Machinery gene |
| NMBH4476_RS07240 (NMBH4476_1284) | pilK | 1389151..1389744 (-) | 594 | WP_002244085.1 | PilX N-terminal domain-containing pilus assembly protein | Machinery gene |
| NMBH4476_RS07245 (NMBH4476_1285) | pilJ | 1389723..1390664 (-) | 942 | WP_033911581.1 | PilW family protein | Machinery gene |
| NMBH4476_RS07250 (NMBH4476_1286) | pilV | 1390661..1391281 (-) | 621 | WP_002225360.1 | type IV pilus modification protein PilV | Machinery gene |
| NMBH4476_RS07255 (NMBH4476_1287) | pilH | 1391305..1391973 (-) | 669 | WP_002230433.1 | Tfp pilus assembly protein FimT/FimU | Machinery gene |
Sequence
Protein
Download Length: 157 a.a. Molecular weight: 17521.30 Da Isoelectric Point: 9.4258
>NTDB_id=48055 NMBH4476_RS07235 WP_002225356.1 1388673..1389146(-) (pilX) [Neisseria meningitidis H44/76]
MEQKGFTLIEMMIVVAILGIISVIAIPSYQSYIEKGYQSQLYTEMVGINNISKQFILKNPLDDNQTIENKLEIFVSGYKM
NPKIAKKYSVSVKFVDKEKSRAYRLVGVPKAGTGYTLSVWMNSVGDGYKCRDAASAQAHLETLSSDVGCEAFSNRKK
MEQKGFTLIEMMIVVAILGIISVIAIPSYQSYIEKGYQSQLYTEMVGINNISKQFILKNPLDDNQTIENKLEIFVSGYKM
NPKIAKKYSVSVKFVDKEKSRAYRLVGVPKAGTGYTLSVWMNSVGDGYKCRDAASAQAHLETLSSDVGCEAFSNRKK
Nucleotide
Download Length: 474 bp
>NTDB_id=48055 NMBH4476_RS07235 WP_002225356.1 1388673..1389146(-) (pilX) [Neisseria meningitidis H44/76]
ATGGAACAAAAAGGGTTTACATTGATTGAGATGATGATAGTCGTCGCGATACTCGGCATTATCAGCGTCATTGCCATACC
TTCTTATCAAAGTTATATTGAAAAAGGCTATCAGTCCCAGCTTTATACGGAGATGGTCGGTATCAACAATATTTCCAAAC
AGTTTATTTTGAAAAATCCCCTGGACGATAATCAGACCATCGAGAACAAACTGGAAATATTTGTCTCAGGCTATAAGATG
AATCCGAAAATTGCCAAAAAATATAGTGTTTCGGTAAAGTTTGTCGATAAGGAAAAATCAAGGGCATACAGGTTGGTCGG
CGTTCCGAAGGCGGGGACGGGTTATACTTTGTCGGTATGGATGAACAGCGTGGGCGACGGATACAAATGCCGTGATGCCG
CTTCTGCCCAAGCCCATTTGGAGACCTTGTCCTCAGATGTCGGCTGTGAAGCCTTCTCTAATCGTAAAAAATAA
ATGGAACAAAAAGGGTTTACATTGATTGAGATGATGATAGTCGTCGCGATACTCGGCATTATCAGCGTCATTGCCATACC
TTCTTATCAAAGTTATATTGAAAAAGGCTATCAGTCCCAGCTTTATACGGAGATGGTCGGTATCAACAATATTTCCAAAC
AGTTTATTTTGAAAAATCCCCTGGACGATAATCAGACCATCGAGAACAAACTGGAAATATTTGTCTCAGGCTATAAGATG
AATCCGAAAATTGCCAAAAAATATAGTGTTTCGGTAAAGTTTGTCGATAAGGAAAAATCAAGGGCATACAGGTTGGTCGG
CGTTCCGAAGGCGGGGACGGGTTATACTTTGTCGGTATGGATGAACAGCGTGGGCGACGGATACAAATGCCGTGATGCCG
CTTCTGCCCAAGCCCATTTGGAGACCTTGTCCTCAGATGTCGGCTGTGAAGCCTTCTCTAATCGTAAAAAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilX | Neisseria meningitidis 8013 |
92.994 |
100 |
0.93 |
| pilL | Neisseria gonorrhoeae MS11 |
88.535 |
100 |
0.885 |