Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   IBL27_RS01300 Genome accession   NZ_CP061071
Coordinates   262484..263809 (+) Length   441 a.a.
NCBI ID   WP_002308983.1    Uniprot ID   -
Organism   Streptococcus mutans B04Sm5     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 257484..268809
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IBL27_RS01275 (IBL27_01275) dnaI 257655..258554 (+) 900 WP_002308985.1 primosomal protein DnaI -
  IBL27_RS01280 (IBL27_01280) der 258567..259877 (+) 1311 WP_002272420.1 ribosome biogenesis GTPase Der -
  IBL27_RS01285 (IBL27_01285) - 259952..260578 (+) 627 WP_002278266.1 hypothetical protein -
  IBL27_RS01290 (IBL27_01290) - 260626..261264 (+) 639 WP_002265117.1 VTT domain-containing protein -
  IBL27_RS01295 (IBL27_01295) comE/blpR 261735..262487 (+) 753 WP_002270252.1 response regulator transcription factor Regulator
  IBL27_RS01300 (IBL27_01300) comD/blpH 262484..263809 (+) 1326 WP_002308983.1 sensor histidine kinase Regulator
  IBL27_RS01305 (IBL27_01305) comC/blpC 263978..264109 (-) 132 WP_002268639.1 ComC/BlpC family leader-containing pheromone/bacteriocin Regulator
  IBL27_RS01310 (IBL27_01310) cipB 264376..264606 (+) 231 WP_002309764.1 Blp family class II bacteriocin Regulator
  IBL27_RS01315 (IBL27_01315) - 264737..265138 (+) 402 WP_002310604.1 hypothetical protein -
  IBL27_RS01320 (IBL27_01320) - 266518..266937 (+) 420 WP_002263913.1 hypothetical protein -
  IBL27_RS01325 (IBL27_01325) - 267084..267488 (+) 405 WP_002263912.1 hypothetical protein -
  IBL27_RS09845 - 267611..267823 (-) 213 Protein_238 IS3 family transposase -
  IBL27_RS01330 (IBL27_01330) - 268263..268427 (+) 165 WP_002265308.1 hypothetical protein -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 50529.80 Da        Isoelectric Point: 9.8662

>NTDB_id=480227 IBL27_RS01300 WP_002308983.1 262484..263809(+) (comD/blpH) [Streptococcus mutans B04Sm5]
MNEALMILSNGLLTYLTVLFLLFLFSKVSNVTLSKKELTLFSISNFLIMIAVTMVNVNLFYPAEPLYFIVLSIYLNRQNS
LSLNIFYGLLPVASSDLFRRAIIFFILDGNQGIVMDSSIITTYMIEFAGIALSYLFLSVFNVDIGRLKDSLTKMKVKKRL
IPMNITMLLYYLLIQALYIIESYNVIPVLKFRKFVVIVYLILFLILISFLSQYTKQKVQNEIMAQKEAQIRNITQYSQQI
ESLYKDIQSFRHDYLNILTSLRLGIENKDLASIEKIYHQILEKTGHQLQDTRYNIGHLANIQNDAVKGILSAKILEAQNK
KIAVNVEVSSKIQLPDMELLDFITILSILCDNAIEAALESLKPKVQLAFFKKNGSIVFIIQNSTKEKQIDVSKIFKENYS
TKGPNRGIGLAKVNHILEHYPKTSLQTSSHHHLFKQLLIIK

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=480227 IBL27_RS01300 WP_002308983.1 262484..263809(+) (comD/blpH) [Streptococcus mutans B04Sm5]
ATGAATGAAGCCTTAATGATACTTTCAAATGGTTTATTAACTTATCTAACCGTTCTATTTCTCTTGTTTCTATTTTCCAA
GGTAAGTAATGTCACTTTATCGAAAAAGGAATTAACTCTTTTTTCGATAAGCAATTTTCTGATAATGATTGCTGTTACGA
TGGTAAATGTAAACCTGTTTTATCCTGCAGAGCCTCTTTATTTTATAGTTTTATCAATTTATCTTAATAGACAGAATAGT
CTTTCTCTAAATATATTTTATGGTCTGCTGCCTGTTGCCAGTTCTGACTTGTTTAGGCGGGCAATCATATTCTTTATCTT
GGATGGAAATCAAGGAATTGTAATGGACAGTAGCATTATAACCACCTATATGATCGAGTTTGCAGGAATAGCGCTAAGTT
ACCTCTTTCTAAGTGTGTTCAATGTTGATATTGGTCGACTTAAAGATAGTTTGACCAAGATGAAGGTCAAAAAACGCTTG
ATCCCAATGAATATTACTATGCTTCTATACTACCTTTTAATACAGGCATTGTATATTATAGAGAGTTATAATGTGATACC
GGTTTTAAAATTTCGTAAATTTGTCGTTATTGTCTATCTTATTTTATTTTTGATTCTGATCTCATTTTTAAGCCAATATA
CCAAACAAAAGGTTCAAAATGAGATAATGGCACAAAAGGAAGCTCAGATTCGAAATATTACCCAGTATAGTCAGCAGATA
GAATCTCTTTACAAGGATATTCAAAGTTTCCGCCATGATTATCTGAATATTTTAACTAGCCTCAGATTAGGCATTGAAAA
TAAAGATTTAGCTAGTATTGAAAAGATTTACCATCAAATCTTAGAAAAAACAGGACATCAATTGCAGGATACCCGTTATA
ATATCGGTCATCTAGCTAATATCCAAAACGATGCTGTCAAGGGTATCTTGTCAGCAAAAATTTTAGAAGCTCAGAATAAA
AAGATTGCTGTCAATGTAGAAGTCTCAAGTAAAATACAACTGCCTGATATGGAGTTGCTTGATTTCATTACCATACTTTC
TATCTTGTGTGATAATGCTATTGAGGCCGCTCTCGAATCACTAAAACCTAAAGTTCAGTTAGCCTTTTTTAAGAAAAATG
GCAGCATAGTCTTTATCATTCAGAATTCCACCAAAGAAAAACAAATAGATGTGAGTAAAATTTTTAAAGAAAACTATTCC
ACTAAAGGCCCCAATCGCGGTATTGGTTTAGCAAAGGTGAATCATATTCTTGAACATTATCCCAAAACTAGTTTACAAAC
AAGCAGTCATCATCATTTATTCAAGCAACTCCTAATAATAAAATAG

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(337-440)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

96.825

100

0.968