Detailed information    

insolico Bioinformatically predicted

Overview

Name   dsbA1   Type   Machinery gene
Locus tag   NMBM04240196_RS02320 Genome accession   NC_017515
Coordinates   423264..423908 (+) Length   214 a.a.
NCBI ID   WP_002226073.1    Uniprot ID   A0A378VTS6
Organism   Neisseria meningitidis M04-240196     
Function   DNA binding and uptake; interact with PilQ (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 418264..428908
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMBM04240196_RS02295 (NMBM04240196_0409) putP 418471..419997 (-) 1527 WP_002227025.1 sodium/proline symporter PutP -
  NMBM04240196_RS02305 (NMBM04240196_0410) - 420480..420800 (+) 321 WP_002216505.1 accessory factor UbiK family protein -
  NMBM04240196_RS02310 (NMBM04240196_0411) comM 420814..422310 (+) 1497 WP_014581352.1 YifB family Mg chelatase-like AAA ATPase Machinery gene
  NMBM04240196_RS02315 (NMBM04240196_0412) ftsN 422416..423261 (+) 846 WP_002226072.1 cell division protein FtsN -
  NMBM04240196_RS02320 (NMBM04240196_0413) dsbA1 423264..423908 (+) 645 WP_002226073.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  NMBM04240196_RS02325 (NMBM04240196_0414) - 423941..424762 (+) 822 WP_002226074.1 undecaprenyl-diphosphate phosphatase -
  NMBM04240196_RS02340 (NMBM04240196_0417) - 425343..426560 (-) 1218 WP_014581353.1 class I SAM-dependent methyltransferase -
  NMBM04240196_RS02345 (NMBM04240196_0418) mraZ 426839..427294 (+) 456 WP_002212482.1 division/cell wall cluster transcriptional repressor MraZ -
  NMBM04240196_RS02350 (NMBM04240196_0419) rsmH 427291..428277 (+) 987 WP_014581354.1 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH -
  NMBM04240196_RS02355 (NMBM04240196_0420) ftsL 428274..428537 (+) 264 WP_002220363.1 cell division protein FtsL -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23967.99 Da        Isoelectric Point: 9.8294

>NTDB_id=47995 NMBM04240196_RS02320 WP_002226073.1 423264..423908(+) (dsbA1) [Neisseria meningitidis M04-240196]
MKLKHLLPLLLSAVLSAQAYALTEREDYLVLDKPIPQEQSGKIEVLEFFGYFCVHCHHFDPLLLKLGKALPSDAYLRTEH
VVWQPEMLGLARMAAAVNLSGLKYQANPAVFKAVYEQKIRLENRAVAGKWALSQKGFDGKKLMRAYDSPEAAAAALKMQK
LTEQYGIDSTPTVIVGGKYRVIFNNGFDGGVHTIKELVAKVREERKRQTPAVQK

Nucleotide


Download         Length: 645 bp        

>NTDB_id=47995 NMBM04240196_RS02320 WP_002226073.1 423264..423908(+) (dsbA1) [Neisseria meningitidis M04-240196]
ATGAAGCTCAAACATCTGTTGCCGCTGCTGCTGTCGGCAGTGTTGTCCGCGCAGGCATATGCCCTGACGGAAAGGGAAGA
CTATCTTGTGTTGGATAAACCCATTCCTCAAGAACAGTCGGGTAAAATTGAGGTTTTGGAATTTTTCGGCTATTTCTGCG
TACATTGCCATCATTTCGATCCTTTGTTATTGAAATTGGGCAAGGCATTGCCGTCTGATGCCTATTTGAGGACGGAGCAC
GTGGTCTGGCAGCCTGAAATGCTCGGTCTGGCCAGGATGGCGGCTGCCGTCAATTTGTCGGGTTTGAAATATCAGGCAAA
CCCTGCTGTGTTTAAAGCAGTTTACGAACAAAAAATCCGCTTGGAAAACAGGGCTGTTGCCGGAAAATGGGCTTTGTCTC
AAAAAGGCTTTGACGGCAAAAAACTGATGCGCGCCTATGATTCCCCCGAAGCTGCCGCCGCCGCATTAAAAATGCAGAAA
CTGACGGAACAATACGGTATTGACAGCACGCCGACCGTTATTGTCGGCGGAAAATACCGCGTTATCTTCAATAATGGCTT
TGACGGCGGCGTTCATACGATTAAAGAATTGGTTGCCAAAGTCAGGGAAGAACGCAAGCGTCAGACCCCTGCTGTACAGA
AATAG

Domains

Predicted by InterproScan.

Thioredoxin (Thioredoxin_4)

(42-179)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A378VTS6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dsbA1 Neisseria meningitidis MC58

56.684

87.383

0.495
  dsbA2 Neisseria meningitidis MC58

51.075

86.916

0.444

Multiple sequence alignment