Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   IAU62_RS06990 Genome accession   NZ_CP061029
Coordinates   1428863..1429579 (+) Length   238 a.a.
NCBI ID   WP_002447515.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain Z0118SE0132     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1423863..1434579
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IAU62_RS06965 - 1425263..1426048 (+) 786 WP_002487355.1 carbon-nitrogen family hydrolase -
  IAU62_RS06970 hld 1426429..1426506 (-) 78 WP_002494082.1 delta-hemolysin -
  IAU62_RS06975 - 1426823..1427386 (+) 564 WP_002495668.1 accessory gene regulator AgrB -
  IAU62_RS06980 agrD 1427392..1427532 (+) 141 WP_002447513.1 cyclic lactone autoinducer peptide AgrD -
  IAU62_RS06985 agrC 1427557..1428846 (+) 1290 WP_002447514.1 quorum-sensing sensor histidine kinase AgrC -
  IAU62_RS06990 agrA 1428863..1429579 (+) 717 WP_002447515.1 quorum-sensing response regulator AgrA Regulator
  IAU62_RS06995 - 1429647..1430606 (-) 960 WP_099774858.1 carbohydrate kinase -
  IAU62_RS07000 - 1430613..1432085 (-) 1473 WP_099774860.1 sucrose-6-phosphate hydrolase -
  IAU62_RS07005 - 1432345..1433298 (-) 954 WP_102841575.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27967.00 Da        Isoelectric Point: 5.6250

>NTDB_id=479872 IAU62_RS06990 WP_002447515.1 1428863..1429579(+) (agrA) [Staphylococcus epidermidis strain Z0118SE0132]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELTLATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=479872 IAU62_RS06990 WP_002447515.1 1428863..1429579(+) (agrA) [Staphylococcus epidermidis strain Z0118SE0132]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAACTTTAGCAACAAATGATCCTTATGAGGTCTTAGAGCAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACCAGTCACAGTGAACTCACTTATTTGACGTTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAGGATGATCCATCTGAATTAAAAATGAGAATCATAGATTGTCTTGAAACAGCACATACACGACTCAAATTAT
TATCTAAAGAAAGTAATGTAGATACGATTGAGTTAAAACGTGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGACTCATCGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
GGAATTAGCACAACTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTGATAAACAGGCATAATATTGAATCTATTG
ATTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.395

100

0.874
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.178

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.178

100

0.374