Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   NMBM01240149_RS00230 Genome accession   NC_017514
Coordinates   43243..46377 (+) Length   1044 a.a.
NCBI ID   WP_014580888.1    Uniprot ID   -
Organism   Neisseria meningitidis M01-240149     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 38243..51377
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMBM01240149_RS00215 (NMBM01240149_0040) - 38822..39307 (+) 486 WP_002215245.1 CinA family protein -
  NMBM01240149_RS00220 (NMBM01240149_0041) msrAB 39409..40977 (-) 1569 WP_002224229.1 bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB -
  NMBM01240149_RS00225 (NMBM01240149_0042) pilA 41122..42387 (+) 1266 WP_002215249.1 signal recognition particle-docking protein FtsY Machinery gene
  NMBM01240149_RS00230 (NMBM01240149_0043) pilC 43243..46377 (+) 3135 WP_014580888.1 PilC family type IV pilus tip adhesin Machinery gene
  NMBM01240149_RS00235 (NMBM01240149_0044) yccS 47586..49736 (-) 2151 WP_002240930.1 YccS family putative transporter -
  NMBM01240149_RS00240 (NMBM01240149_0045) - 50022..51248 (-) 1227 WP_002240931.1 PilT/PilU family type 4a pilus ATPase -

Sequence

Protein


Download         Length: 1044 a.a.        Molecular weight: 114763.66 Da        Isoelectric Point: 9.5887

>NTDB_id=47939 NMBM01240149_RS00230 WP_014580888.1 43243..46377(+) (pilC) [Neisseria meningitidis M01-240149]
MNKTLKRQVFRHTALYAAILMFSHTGGGGGAQAETHNYAIVMNNQKLPEVKWGQQYQSLVNKENTRQVIHTSGFGIKKNV
SLSFNNTDEVVAKKNGTVVFGAATYLPPYGKVSGFDEEKLKERTNALDWIGTTDPGLVGYSYENVTCNSGNCPEVSYKTQ
FIFDNHQLAKKKTDSKLDIYEDKSRDNSPIYKLQDYPWLGVSFNLGGESSFKPKRQGSLVSSFSEDVTQQNGTQDQYKGK
NLVYTTEDYNNQGNRNHQDKHHAIAFYLNAKLHLLDKKGIKDITDKTVQLGVLKPRIDLTEAWKNRHGSFFSNGNWTFED
KGAVSVKLILPEVKAGRCINKSNPNPKAQVLSPALTAPALWFGPVQNGKVQMYSASVSTYPDSSSSRIFLQNLKRKTDPG
RPGRYSLATLNKSDIESRKPTFTGRQTIIRLDGGVQQIKLDKSNEATGLNGNTNNNTFGIVKEYSVNPETNEWKKVLLPW
TVRSFSNDNEFVKFNKESDKYSQRYRIRENGNNSKRDLGDIVNSPIVAVGGYLATSANDGMVHIFKKGNGGDDRNYSLKL
SYIPGTMPRKDIESKDSNLAKELRTFAEKSYVGDRYGVDGGFVLRKVDNLNGQNRVFMFGAMGFGGRGAYALDLTKADGS
DPTKASLFDVKDNGNNGNNRVELGYTVGTPQIGKTHDGKYAAFLASGYATKEINSTDNKTALYVYDLESSGTLIKKIDVP
GGKGGLSSPTLVDKDLDGIVDIAYAGDRGGKMYRFDLSNQDSSQWTVRTIFEGTKPITSAPAISQLKDKRVVIFGTGSDL
SEEDVDNNDIQSIYGIFDNDTDTGFAQDGLGKGLLEQKLEKDKDGKTLFLSDYKRSDGSGDKGWVVKLEAGQRVTVKPTV
VLRTAFVTIHKYTGNDKCGAETAILGINTADGGKLTKKSARPIVPEANTAVAQYSGHKKTSSGKSIPIGCMEKGNETVCP
NGYVYGKPVNVRYLDEKKTDGFSTTADGDAGGSGIDPAGKRSGKNNRCFSQKGVRTLLMNDLDSLDITGPTCGMKRISWR
EIFY

Nucleotide


Download         Length: 3135 bp        

>NTDB_id=47939 NMBM01240149_RS00230 WP_014580888.1 43243..46377(+) (pilC) [Neisseria meningitidis M01-240149]
ATGAATAAAACTTTAAAAAGGCAGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGGCGCAGGCGGAAACCCATAACTACGCTATTGTAATGAACAATCAAAAGCTGCCTGAGGTAAAGTGGGGGC
AACAATATCAATCATTGGTGAACAAAGAAAATACCCGTCAAGTTATCCATACGAGTGGTTTTGGAATCAAAAAAAACGTA
AGTTTATCATTCAATAATACCGATGAAGTTGTTGCTAAAAAAAACGGTACTGTCGTTTTCGGCGCAGCGACCTACCTGCC
GCCCTACGGCAAGGTTTCCGGTTTTGATGAAGAAAAGCTGAAAGAGCGCACCAATGCCCTTGATTGGATTGGTACGACCG
ACCCAGGGTTGGTAGGCTACAGCTACGAAAATGTTACATGCAACAGCGGCAACTGTCCTGAAGTTAGCTATAAAACCCAA
TTTATCTTCGATAATCACCAGTTGGCAAAAAAGAAAACAGACAGCAAGCTGGATATATACGAAGACAAAAGCCGCGACAA
TTCGCCCATTTACAAATTGCAGGATTATCCTTGGTTGGGCGTGTCTTTCAATTTGGGCGGAGAGAGCTCCTTCAAACCAA
AGAGACAAGGTTCTTTGGTATCTTCTTTTAGCGAGGATGTGACGCAGCAAAATGGTACACAAGACCAATACAAAGGCAAA
AACCTCGTTTATACGACAGAAGATTACAATAATCAGGGTAATCGTAACCATCAGGACAAACACCACGCCATCGCCTTTTA
TCTGAACGCCAAACTGCACCTGCTGGATAAAAAAGGGATTAAAGATATCACCGACAAAACAGTGCAGTTGGGTGTCTTGA
AACCGCGCATCGATTTGACGGAAGCGTGGAAAAACAGGCATGGGAGCTTTTTTAGTAATGGTAATTGGACGTTTGAAGAT
AAAGGAGCAGTCAGCGTCAAACTTATCTTGCCGGAAGTCAAAGCAGGCCGCTGCATCAATAAATCGAACCCCAATCCCAA
AGCCCAAGTCCTTTCCCCCGCACTGACTGCCCCCGCGCTGTGGTTCGGACCTGTGCAAAATGGTAAGGTGCAGATGTATT
CCGCTTCGGTTTCTACCTACCCCGACAGTTCGAGCAGCCGCATCTTCCTTCAAAATCTGAAAAGAAAAACCGACCCCGGC
AGACCCGGCCGCTATTCCCTCGCAACCTTGAATAAGTCGGATATTGAAAGTCGAAAGCCGACTTTCACAGGGCGGCAAAC
AATCATCCGATTGGATGGCGGCGTACAGCAGATCAAACTGGATAAAAGCAATGAGGCCACCGGTTTAAATGGAAATACCA
ACAACAACACTTTCGGCATTGTTAAGGAATATAGCGTCAATCCTGAGACCAATGAGTGGAAAAAAGTGCTGCTGCCTTGG
ACGGTTCGGAGTTTTAGTAATGACAATGAATTTGTAAAATTCAACAAAGAATCAGACAAATACAGCCAAAGATACCGCAT
CCGCGAAAACGGCAACAACAGCAAGCGCGATTTGGGCGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGGGTATTTGG
CTACTTCCGCCAACGACGGGATGGTGCATATCTTCAAAAAAGGCAACGGCGGGGATGACCGCAACTATAGTCTGAAGCTC
AGCTACATCCCCGGCACGATGCCGCGCAAGGATATTGAAAGCAAAGACTCCAACCTCGCCAAAGAGCTGCGCACCTTTGC
CGAAAAAAGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTTTTGCGCAAAGTTGATAACTTAAACGGGCAAA
ACCGCGTGTTTATGTTCGGCGCGATGGGCTTTGGCGGCAGAGGCGCATACGCCTTGGATTTGACCAAAGCCGACGGCAGT
GACCCGACAAAAGCCTCTTTGTTTGATGTAAAAGATAACGGCAATAATGGCAATAATCGCGTGGAATTAGGCTACACCGT
CGGCACGCCGCAAATCGGCAAAACCCACGACGGCAAATACGCCGCTTTCCTCGCCTCCGGTTATGCGACTAAAGAAATTA
ACAGCACAGACAATAAAACCGCGCTGTATGTGTATGATTTGGAAAGCAGCGGCACGCTGATTAAAAAAATCGATGTACCC
GGCGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCATTGTCGATATCGCCTATGCCGGCGA
TCGCGGCGGCAAGATGTACCGCTTTGATTTAAGCAATCAAGATTCTAGTCAATGGACTGTACGCACTATTTTTGAAGGCA
CAAAACCGATTACTTCCGCGCCCGCCATTTCCCAACTGAAAGACAAACGCGTGGTTATCTTCGGCACGGGCAGTGATTTG
AGTGAGGAGGATGTTGATAATAATGATATACAATCTATTTACGGTATTTTTGACAATGACACAGACACGGGTTTTGCGCA
AGACGGGCTGGGCAAAGGGCTGCTCGAGCAAAAGCTGGAAAAAGACAAAGACGGCAAAACGCTGTTTTTAAGCGACTACA
AAAGGTCTGACGGCTCGGGCGACAAGGGCTGGGTAGTGAAATTGGAAGCCGGACAGCGCGTTACCGTCAAACCGACCGTG
GTATTGCGTACCGCCTTTGTAACCATCCATAAATATACGGGTAATGACAAATGCGGCGCGGAAACCGCCATTTTGGGCAT
CAATACTGCCGACGGCGGCAAGCTGACCAAGAAAAGCGCGCGCCCGATTGTGCCGGAAGCCAATACGGCTGTCGCGCAAT
ATTCCGGCCATAAGAAAACTTCCAGCGGCAAATCCATCCCTATAGGTTGTATGGAAAAAGGCAATGAAACCGTCTGCCCG
AACGGATATGTTTACGGCAAACCGGTTAATGTGCGTTATCTGGATGAAAAGAAAACAGACGGATTTTCAACAACGGCAGA
CGGCGATGCGGGCGGCAGCGGTATAGACCCCGCCGGCAAGCGTTCCGGCAAAAACAACCGCTGCTTCTCCCAAAAAGGGG
TGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGACATTACCGGCCCGACGTGCGGTATGAAACGAATCAGCTGGCGT
GAAATCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(518-851)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

72.762

100

0.739

Multiple sequence alignment