Detailed information NTG0047938

Bioinformatically predicted

Overview

• Name: pilA
• Type: Machinery gene
• Locus tag: NMBM01240149_RS00225
• Genome accession: NC_017514
• Coordinates: 41122..42387 (+)
• Length: 421 a.a.
• NCBI ID: WP_002215249.1
• Uniprot ID: A0A425AK53
• Organism: Neisseria meningitidis M01-240149
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 36122..47387

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMBM01240149_RS00205 (NMBM01240149_0038)	-	36853..37854 (+)	1002	WP_002223261.1	thiamine ABC transporter substrate-binding protein	-
NMBM01240149_RS00210 (NMBM01240149_0039)	-	37948..38796 (+)	849	WP_002215243.1	mechanosensitive ion channel family protein	-
NMBM01240149_RS00215 (NMBM01240149_0040)	-	38822..39307 (+)	486	WP_002215245.1	CinA family protein	-
NMBM01240149_RS00220 (NMBM01240149_0041)	msrAB	39409..40977 (-)	1569	WP_002224229.1	bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB	-
NMBM01240149_RS00225 (NMBM01240149_0042)	pilA	41122..42387 (+)	1266	WP_002215249.1	signal recognition particle-docking protein FtsY	Machinery gene
NMBM01240149_RS00230 (NMBM01240149_0043)	pilC	43243..46377 (+)	3135	WP_014580888.1	PilC family type IV pilus tip adhesin	Machinery gene

Sequence

Protein

• Length: 421 a.a.
• Molecular weight: 45185.50 Da
• Isoelectric Point: 4.5585

>NTDB_id=47938 NMBM01240149_RS00225 WP_002215249.1 41122..42387(+) (pilA) [Neisseria meningitidis M01-240149]
MFSFFRRKKKQETPAPEEAQVQETAAKAESEVTQIVENIKEEVESLTESVKGQVESAVETVSGAVEQVKEAVAEMLSEAE
EAAEKAAEQVEAAKEAIAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLTKSRDKMAKSLAGVFGGGQIDEDLYEELET
VLITSDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGK
LAKYFQAQGKSVLLAAGDTFRAAAREQLQAWGERNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHL
MEEIKKVKRVLQKAMPDAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGV
GEGIDDLRPFDARAFVDALLD

Nucleotide

• Length: 1266 bp

>NTDB_id=47938 NMBM01240149_RS00225 WP_002215249.1 41122..42387(+) (pilA) [Neisseria meningitidis M01-240149]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCCCGAGGAGGCTCAAGTTCAGGAAACTGCAGCAAA
AGCAGAATCCGAAGTTACTCAAATAGTTGAAAATATTAAAGAAGAAGTCGAATCTTTAACGGAAAGCGTCAAAGGGCAGG
TCGAATCGGCTGTTGAAACCGTCAGCGGTGCGGTTGAACAAGTAAAGGAAGCCGTTGCCGAGATGCTGTCTGAAGCAGAG
GAAGCGGCGGAAAAAGCAGCGGAACAAGTCGAAGCGGCAAAAGAAGCCATTGCCGAAACCGTCGGCGAGGCTGTCGGGCA
AGTTCAAGAAGCCGTTGCAACAACTGAAGAACACAAGCTCGGTTGGGCGGCGCGTTTGAAACAAGGTTTGACCAAATCGC
GCGACAAAATGGCGAAATCGCTGGCGGGCGTGTTCGGCGGCGGACAAATCGACGAAGATTTGTACGAAGAGCTGGAAACC
GTGCTGATTACCAGCGATATGGGCATGGAAGCCACCGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGG
GCTGAAAGACGGCAACGAATTGCGCGGCGCGCTGAAAGAAGCCTTGTACGACCTGATTAAGCCTCTAGAGAAACCGCTGG
TTTTGCCCGAAACCAAAGAGCCGTTTGTCATCATGCTTGCTGGCATCAACGGCGCGGGCAAAACCACATCCATCGGCAAA
CTCGCCAAATATTTCCAAGCGCAGGGCAAATCTGTGCTGCTTGCCGCCGGCGATACTTTCCGCGCCGCCGCGCGTGAGCA
GCTTCAAGCTTGGGGCGAACGCAACAACGTAACCGTGATTTCGCAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATG
CCGTCCAAGCCGCCAAAGCGCGCGGCATCGACATTGTGCTGGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCACTTG
ATGGAAGAAATCAAAAAAGTGAAACGCGTGCTGCAAAAAGCCATGCCCGACGCGCCGCACGAAATCATCGTCGTGCTTGA
TGCCAATATCGGTCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTAGGGCTGACCGGTTTAATCGTGACCA
AACTCGACGGCACGGCAAAAGGCGGCATCCTCGCCGCGCTTGCCTCCGACCGCCCCGTCCCCGTCCGCTACATCGGCGTG
GGCGAAGGCATAGACGATTTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

• SRP54-type protein, GTPase domain (SRP54) (221-420)

• SRP54-type protein, helical bundle domain (SRP54_N) (136-202)

3D structure

• AlphaFold DB: A0A425AK53

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilA	Neisseria gonorrhoeae MS11	94.062	100	0.941