Detailed information    

insolico Bioinformatically predicted

Overview

Name   dsbA2   Type   Machinery gene
Locus tag   NMBG2136_RS10050 Genome accession   NC_017513
Coordinates   1920659..1921354 (-) Length   231 a.a.
NCBI ID   WP_002215704.1    Uniprot ID   Q7DDR6
Organism   Neisseria meningitidis G2136     
Function   DNA binding and uptake; interact with PilQ (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1904957..1922184 1920659..1921354 within 0


Gene organization within MGE regions


Location: 1904957..1922184
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMBG2136_RS09960 (NMBG2136_1787) - 1906345..1906590 (-) 246 WP_002226028.1 hypothetical protein -
  NMBG2136_RS09970 (NMBG2136_1788) - 1906702..1907130 (+) 429 WP_002226027.1 CopD family protein -
  NMBG2136_RS09975 (NMBG2136_1789) - 1907142..1907618 (+) 477 WP_002226026.1 CYTH domain-containing protein -
  NMBG2136_RS09980 (NMBG2136_1790) - 1907968..1908456 (-) 489 WP_002226025.1 dihydrofolate reductase -
  NMBG2136_RS09985 (NMBG2136_1791) aroG 1908524..1909579 (-) 1056 WP_002226024.1 3-deoxy-7-phosphoheptulonate synthase AroG -
  NMBG2136_RS14580 - 1909741..1909968 (-) 228 WP_153310284.1 hypothetical protein -
  NMBG2136_RS09990 (NMBG2136_1793) - 1910194..1910502 (+) 309 WP_017629289.1 membrane protein -
  NMBG2136_RS14995 (NMBG2136_1794) - 1910551..1910655 (-) 105 Protein_1851 IS1595 family transposase -
  NMBG2136_RS09995 (NMBG2136_1795) - 1910759..1910965 (-) 207 WP_002220254.1 hypothetical protein -
  NMBG2136_RS10000 (NMBG2136_1796) comP 1911132..1911581 (-) 450 WP_002221685.1 type IV pilin protein Machinery gene
  NMBG2136_RS10005 (NMBG2136_1797) comE 1911669..1912133 (-) 465 WP_011799029.1 helix-hairpin-helix domain-containing protein Machinery gene
  NMBG2136_RS10040 (NMBG2136_1803) - 1917932..1918738 (-) 807 WP_002221447.1 cytochrome C assembly family protein -
  NMBG2136_RS10045 (NMBG2136_1804) ffh 1918958..1920328 (+) 1371 WP_002221448.1 signal recognition particle protein -
  NMBG2136_RS10050 (NMBG2136_1805) dsbA2 1920659..1921354 (-) 696 WP_002215704.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  NMBG2136_RS10055 (NMBG2136_1806) - 1921525..1922184 (-) 660 WP_002218694.1 NYN domain-containing protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 25419.90 Da        Isoelectric Point: 5.1502

>NTDB_id=47929 NMBG2136_RS10050 WP_002215704.1 1920659..1921354(-) (dsbA2) [Neisseria meningitidis G2136]
MKLKTLALTSLTLLALAACSKQAETSVPADSAQSSSSAPAAPAELNEGVNYTVLSTPIPQQQAGKIEVLEFFGYFCPHCA
HLEPVLSEHIKTFKDDTYMRREHVVWGDEMKPLARLAAAVEMAGESDKANSHIFDAMVNQKINLADTDTLKKWLSEQTAF
DGKKVLAAFEAPESQARAAQMEELTNKFQISGTPTVIVGGKYQVEFKDWQSGMTTIDQLVDKVREEQKKPQ

Nucleotide


Download         Length: 696 bp        

>NTDB_id=47929 NMBG2136_RS10050 WP_002215704.1 1920659..1921354(-) (dsbA2) [Neisseria meningitidis G2136]
ATGAAACTGAAAACCTTAGCTTTGACTTCATTGACCCTGTTGGCATTGGCCGCTTGTAGCAAACAGGCTGAAACCAGTGT
TCCGGCAGACAGCGCCCAAAGCAGCTCATCTGCTCCGGCAGCCCCTGCTGAGTTGAACGAAGGTGTGAACTACACTGTAT
TGTCTACGCCTATTCCGCAACAGCAGGCCGGTAAAATCGAAGTATTGGAATTTTTCGGCTACTTCTGCCCGCATTGCGCC
CATCTTGAGCCGGTCTTGAGCGAGCACATCAAAACGTTTAAAGACGATACCTATATGCGCCGGGAGCATGTCGTGTGGGG
TGATGAAATGAAACCTTTGGCACGTTTGGCGGCCGCAGTGGAAATGGCCGGTGAATCAGATAAAGCCAACAGCCATATTT
TCGATGCGATGGTTAATCAAAAAATCAATCTGGCCGATACCGATACCCTGAAAAAATGGCTGTCCGAGCAAACAGCGTTT
GACGGCAAAAAAGTATTGGCTGCATTTGAGGCTCCTGAAAGCCAAGCGCGTGCGGCTCAAATGGAAGAGTTGACCAATAA
ATTCCAAATCAGCGGCACACCGACTGTGATTGTCGGCGGCAAATACCAAGTTGAATTTAAAGACTGGCAGTCTGGTATGA
CCACGATTGACCAGTTGGTGGATAAAGTACGCGAAGAGCAGAAAAAGCCGCAATAA

Domains

Predicted by InterproScan.

Thioredoxin (Thioredoxin_4)

(65-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q7DDR6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dsbA2 Neisseria meningitidis MC58

100

100

1
  dsbA1 Neisseria meningitidis MC58

71.245

100

0.719

Multiple sequence alignment