Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JQM62_RS24840 Genome accession   NZ_CP071711
Coordinates   5023635..5024291 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain EC20017429     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 5018635..5029291
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JQM62_RS24810 (JQM62_24605) dcyD 5019515..5020501 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  JQM62_RS24815 (JQM62_24610) tcyL 5020516..5021184 (+) 669 WP_001158206.1 cystine ABC transporter permease -
  JQM62_RS24820 (JQM62_24615) tcyN 5021181..5021933 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JQM62_RS24825 (JQM62_24620) sdiA 5022163..5022885 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  JQM62_RS24830 (JQM62_24625) yecF 5022952..5023176 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  JQM62_RS24835 (JQM62_24630) yecU 5023163..5023339 (-) 177 WP_000590347.1 protein YecU -
  JQM62_RS30250 - 5023422..5023493 (-) 72 Protein_4871 transcriptional regulator -
  JQM62_RS24840 (JQM62_24635) letA 5023635..5024291 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JQM62_RS24845 (JQM62_24640) uvrC 5024288..5026120 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  JQM62_RS24850 (JQM62_24645) pgsA 5026177..5026725 (+) 549 WP_001160189.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JQM62_RS24870 (JQM62_24665) - 5027720..5028001 (+) 282 WP_071529678.1 hypothetical protein -
  JQM62_RS24875 (JQM62_24670) - 5028191..5028331 (-) 141 WP_000078920.1 Hok/Gef family protein -
  JQM62_RS24880 (JQM62_24675) - 5028521..5028781 (-) 261 WP_000488107.1 ogr/Delta-like zinc finger family protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=478566 JQM62_RS24840 WP_000611335.1 5023635..5024291(+) (letA) [Escherichia coli strain EC20017429]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=478566 JQM62_RS24840 WP_000611335.1 5023635..5024291(+) (letA) [Escherichia coli strain EC20017429]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486