Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilE   Type   Machinery gene
Locus tag   NMBB_RS00105 Genome accession   NC_017505
Coordinates   17389..17898 (-) Length   169 a.a.
NCBI ID   WP_014575067.1    Uniprot ID   -
Organism   Neisseria meningitidis alpha710     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 12389..22898
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMBB_RS00090 (NMBB_0018) gnd 13072..14520 (-) 1449 WP_014575066.1 decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase -
  NMBB_RS00100 (NMBB_0020) lpxC 15793..16716 (-) 924 WP_002233293.1 UDP-3-O-acyl-N-acetylglucosamine deacetylase -
  NMBB_RS00105 (NMBB_0021) pilE 17389..17898 (-) 510 WP_014575067.1 pilin Machinery gene
  NMBB_RS00115 (NMBB_0023) - 18658..19035 (-) 378 Protein_19 pilin -
  NMBB_RS00120 (NMBB_0024) - 19037..19453 (-) 417 Protein_20 pilin -
  NMBB_RS00125 (NMBB_0025) - 19863..20282 (-) 420 Protein_21 pilin -
  NMBB_RS00130 (NMBB_0026) - 21021..21389 (-) 369 Protein_22 pilin -
  NMBB_RS00135 (NMBB_0027) - 21573..21908 (-) 336 Protein_23 pilin -
  NMBB_RS00140 (NMBB_0028) - 22126..22503 (-) 378 Protein_24 pilin -

Sequence

Protein


Download         Length: 169 a.a.        Molecular weight: 18096.53 Da        Isoelectric Point: 8.4525

>NTDB_id=47768 NMBB_RS00105 WP_014575067.1 17389..17898(-) (pilE) [Neisseria meningitidis alpha710]
MNTLQKGFTLIELMIVIAIVGILAAVALPAYQDYTARAQVSEAILLAEGQKSAVTEYYLNHGIWPGDNSSAGVASSSTIK
GKYVKSVEVKNGVITAQMASSNVNNEIKDKKLSLWAKRQDGSVKWFCGQPVTRNAGAKADDVTADTTSTDKKIDTKHLPS
TCRDESSAT

Nucleotide


Download         Length: 510 bp        

>NTDB_id=47768 NMBB_RS00105 WP_014575067.1 17389..17898(-) (pilE) [Neisseria meningitidis alpha710]
ATGAACACCCTTCAAAAAGGTTTTACCCTTATCGAGCTGATGATTGTGATTGCCATCGTCGGCATTTTGGCGGCAGTCGC
CCTTCCTGCTTATCAAGACTACACAGCCCGCGCACAAGTTTCCGAAGCCATTCTTTTGGCTGAAGGTCAAAAATCAGCCG
TCACCGAGTATTACCTGAATCACGGCATATGGCCCGGCGACAACAGTTCTGCCGGCGTGGCATCTTCTTCAACAATCAAA
GGCAAATATGTTAAAAGCGTTGAAGTCAAAAACGGCGTCATTACCGCCCAAATGGCTTCAAGCAACGTAAACAATGAAAT
CAAAGACAAAAAACTCTCCCTGTGGGCCAAGCGTCAAGACGGTTCGGTAAAATGGTTCTGCGGACAGCCGGTTACGCGCA
ACGCCGGCGCCAAAGCCGACGACGTTACCGCCGACACCACCAGCACCGACAAGAAGATCGACACCAAGCACCTGCCGTCA
ACCTGCCGCGATGAAAGTAGTGCTACCTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(5-28)

Pilin (bacterial filament) (Pilin)

(36-163)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilE Neisseria gonorrhoeae strain FA1090

84.024

100

0.84
  pilE Neisseria gonorrhoeae MS11

80.357

99.408

0.799
  comP Acinetobacter baylyi ADP1

38.69

99.408

0.385

Multiple sequence alignment