Detailed information    

insolico Bioinformatically predicted

Overview


Name   comE   Type   Machinery gene
Locus tag   NMV_RS15395 Genome accession   NC_017501
Coordinates   2138475..2138939 (-) Length   154 a.a.
NCBI ID   WP_014574275.1    Uniprot ID   -
Organism   Neisseria meningitidis 8013     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2128693..2138774 2138475..2138939 flank -299


Gene organization within MGE regions


Location: 2128693..2138939
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMV_RS10905 (NMV_2208) - 2128693..2129685 (+) 993 WP_014574273.1 DNA cytosine methyltransferase -
  NMV_RS10910 (NMV_2209) - 2129790..2133200 (+) 3411 WP_048813560.1 DUF3418 domain-containing protein -
  NMV_RS10915 (NMV_2210) - 2133223..2133645 (-) 423 WP_002214928.1 very short patch repair endonuclease -
  NMV_RS10920 (NMV_2211) - 2133649..2135295 (-) 1647 WP_014574274.1 TIGR02391 family protein -
  NMV_RS10925 (NMV_2212) - 2135309..2136364 (-) 1056 WP_002221681.1 DNA cytosine methyltransferase -
  NMV_RS10935 - 2136770..2137242 (-) 473 Protein_2049 transposase -
  NMV_RS16385 (NMV_2215) - 2137580..2137848 (+) 269 Protein_2050 5'-nucleotidase -
  NMV_RS10945 (NMV_2216) comP 2137938..2138387 (-) 450 WP_002218144.1 type IV pilin protein Machinery gene
  NMV_RS15395 (NMV_2217) comE 2138475..2138939 (-) 465 WP_014574275.1 ComEA family DNA-binding protein Machinery gene

Sequence


Protein


Download         Length: 154 a.a.        Molecular weight: 16503.77 Da        Isoelectric Point: 10.9585

>NTDB_id=47765 NMV_RS15395 WP_014574275.1 2138475..2138939(-) (comE) [Neisseria meningitidis 8013]
MLCPEKMSGMAGRHPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCTFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKAPAKPAIPAAKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=47765 NMV_RS15395 WP_014574275.1 2138475..2138939(-) (comE) [Neisseria meningitidis 8013]
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACGGCATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACCCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCACCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGCTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTAGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCGGTCGGTGCGCCCGCACCAAAAGCCCCAGCCAAACCGGCTATACCGGCCGCTAAAAAATAG

Domains


Predicted by InterproScan.

(75-133)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

90.984

79.221

0.721

  comE Neisseria gonorrhoeae MS11

90.984

79.221

0.721

  comE Neisseria gonorrhoeae MS11

90.984

79.221

0.721

  comE Neisseria gonorrhoeae MS11

90.984

79.221

0.721


Multiple sequence alignment