Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   H7789_RS07020 Genome accession   NZ_CP060646
Coordinates   1426985..1427695 (-) Length   236 a.a.
NCBI ID   WP_002985645.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY1026     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1421985..1432695
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7789_RS07005 (H7789_07000) rnc 1423691..1424383 (-) 693 WP_002990670.1 ribonuclease III -
  H7789_RS07010 (H7789_07005) vicX 1424827..1425636 (-) 810 WP_136022319.1 MBL fold metallo-hydrolase Regulator
  H7789_RS07015 (H7789_07010) vicK 1425640..1426992 (-) 1353 WP_002995609.1 cell wall metabolism sensor histidine kinase VicK Regulator
  H7789_RS07020 (H7789_07015) vicR 1426985..1427695 (-) 711 WP_002985645.1 response regulator YycF Regulator
  H7789_RS07025 (H7789_07020) - 1427857..1428891 (-) 1035 WP_172448831.1 DUF3114 domain-containing protein -
  H7789_RS07030 (H7789_07025) - 1428947..1430194 (-) 1248 WP_002995606.1 AMP-binding protein -
  H7789_RS07035 (H7789_07030) - 1430151..1431299 (-) 1149 WP_136261082.1 acetyl-CoA C-acyltransferase -
  H7789_RS07040 (H7789_07035) - 1431704..1431847 (-) 144 WP_136261083.1 dihydroxyacetone kinase -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27083.99 Da        Isoelectric Point: 4.9038

>NTDB_id=477376 H7789_RS07020 WP_002985645.1 1426985..1427695(-) (vicR) [Streptococcus pyogenes strain TSPY1026]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAFVAKKHGQEVE
LTHREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=477376 H7789_RS07020 WP_002985645.1 1426985..1427695(-) (vicR) [Streptococcus pyogenes strain TSPY1026]
ATGAAAAAAATACTTATTGTGGATGATGAAAAACCGATTTCTGACATTATTAAGTTTAATTTGACAAAAGAAGGTTATGA
CATTGTTACAGCTTTTGATGGACGCGAAGCGGTAACAATTTTTGAAGAAGAAAAGCCAGATTTAATTATTCTTGATTTGA
TGCTCCCTGAGTTGGACGGTCTTGAAGTAGCCAAGGAAATTCGTAAAACCAGTCATGTCCCGATTATTATGTTGTCGGCT
AAAGATAGTGAGTTTGACAAGGTTATTGGACTTGAAATTGGGGCTGATGATTACGTGACCAAGCCTTTTTCTAATCGGGA
ATTGCTGGCGCGTGTCAAGGCTCATCTGCGTCGTACCGAAACTATTGAAACGGCTGTTGCAGAAGAAAATGCTTCTTCAG
GTACACAGGAACTAACCATTGGTAATTTACAGATTTTACCAGATGCGTTTGTTGCTAAAAAACATGGTCAAGAGGTAGAG
TTGACCCATCGTGAATTTGAACTATTGCATCATCTAGCTAACCATATGGGTCAGGTGATGACACGAGAACACTTATTGGA
AATTGTTTGGGGATATGATTATTTTGGCGATGTGCGCACGGTTGATGTGACTGTTCGTCGTCTTCGTGAAAAAATTGAAG
ACACACCAAGTCGTCCTGAGTATATTTTAACAAGACGTGGTGTTGGGTACTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.254

100

0.903
  micA Streptococcus pneumoniae Cp1015

79.06

99.153

0.784
  covR Streptococcus salivarius strain HSISS4

44.828

98.305

0.441
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

36.91

98.729

0.364