Detailed information NTG0477377

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: H7789_RS07075
• Genome accession: NZ_CP060646
• Coordinates: 1439618..1440619 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain TSPY1026
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1434618..1445619

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7789_RS07060 (H7789_07055)	thrS	1434788..1436731 (-)	1944	WP_002985672.1	threonine--tRNA ligase	-
H7789_RS07065 (H7789_07060)	-	1437153..1438487 (-)	1335	WP_228628099.1	glycosyltransferase family 4 protein	-
H7789_RS07070 (H7789_07065)	-	1438489..1439487 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
H7789_RS07075 (H7789_07070)	ccpA	1439618..1440619 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
H7789_RS07080 (H7789_07075)	-	1440793..1441878 (+)	1086	WP_002985682.1	aminopeptidase P family protein	-
H7789_RS07085 (H7789_07080)	-	1441927..1442592 (+)	666	WP_136261088.1	NAD(P)H-dependent oxidoreductase	-
H7789_RS07090 (H7789_07085)	-	1442603..1442980 (+)	378	WP_002985686.1	VOC family protein	-
H7789_RS07095 (H7789_07090)	-	1443125..1444051 (+)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
H7789_RS07100 (H7789_07095)	-	1444262..1444945 (+)	684	WP_053308560.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=477377 H7789_RS07075 WP_002985680.1 1439618..1440619(-) (ccpA) [Streptococcus pyogenes strain TSPY1026]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=477377 H7789_RS07075 WP_002985680.1 1439618..1440619(-) (ccpA) [Streptococcus pyogenes strain TSPY1026]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCTCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGACATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559