Detailed information NTG0477368

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: H7789_RS04575
• Genome accession: NZ_CP060646
• Coordinates: 910204..911514 (+)
• Length: 436 a.a.
• NCBI ID: WP_136260995.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY1026
• Function: Required for optimal comC expression (predicted from homology) Competence regulation

Genomic Context

Location: 905204..916514

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7789_RS04560 (H7789_04555)	phoU	905796..906449 (+)	654	WP_002984514.1	phosphate signaling complex protein PhoU	-
H7789_RS04565 (H7789_04560)	-	906654..909191 (+)	2538	WP_115230507.1	M1 family metallopeptidase	-
H7789_RS04570 (H7789_04565)	ciaR	909537..910211 (+)	675	WP_002984519.1	response regulator transcription factor	Regulator
H7789_RS04575 (H7789_04570)	ciaH	910204..911514 (+)	1311	WP_136260995.1	sensor histidine kinase	Regulator
H7789_RS04580 (H7789_04575)	rpsT	911639..911887 (-)	249	WP_009881183.1	30S ribosomal protein S20	-
H7789_RS04585 (H7789_04580)	coaA	911941..912861 (-)	921	WP_010922353.1	type I pantothenate kinase	-
H7789_RS04590 (H7789_04585)	-	913129..913722 (+)	594	WP_002989699.1	class I SAM-dependent methyltransferase	-
H7789_RS04595 (H7789_04590)	-	914325..914714 (+)	390	WP_002984531.1	cytidine deaminase	-
H7789_RS04600 (H7789_04595)	-	914808..915860 (+)	1053	WP_002989701.1	BMP family protein	-

Sequence

Protein

• Length: 436 a.a.
• Molecular weight: 50085.63 Da
• Isoelectric Point: 9.2692

>NTDB_id=477368 H7789_RS04575 WP_136260995.1 910204..911514(+) (ciaH) [Streptococcus pyogenes strain TSPY1026]
MNKLKKEILSDNYNHFFHFFAVFTGIFVIMTIIILQIMRFGVYSSVDSSLVSVSNNASSYANRTMARISSFYFDTENNII
KALPDSDSSKLLGTPAANTDIILFSANGTILNAFDAFSNYQNFHLDKRRLGSIETTSLMNFYGQEEKYHTITVRVHIKNY
PAVAYMMAVVNVEQLDRANERYERIIIIVMSVFWLISILASIYLAKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTHLDTDFFNAIFENYELVAKEYGKIFYFQS
QVNRSLRMDKALLKQLITILFDNAIKYTDKNGIIEIIVKTTDKNLLISVIDNGPGITDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVMSLKGNITVKDNDPKGSIFEVKL

Nucleotide

• Length: 1311 bp

>NTDB_id=477368 H7789_RS04575 WP_136260995.1 910204..911514(+) (ciaH) [Streptococcus pyogenes strain TSPY1026]
ATGAATAAATTAAAAAAAGAGATTTTATCAGATAACTATAACCACTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTCATTATGACTATTATTATCTTACAGATTATGCGGTTTGGCGTTTATTCGTCAGTTGATAGTAGTTTAGTTTCTGTTA
GTAATAATGCAAGTAGCTATGCTAATCGTACGATGGCTAGAATATCTTCTTTTTACTTTGATACTGAAAATAACATTATT
AAGGCGCTGCCTGATTCAGATAGTTCTAAGTTATTAGGAACGCCTGCAGCTAATACAGATATCATTTTGTTTAGTGCTAA
TGGAACAATTTTAAATGCTTTTGATGCGTTTTCTAACTATCAAAATTTTCATTTAGATAAACGCCGGTTGGGGAGTATTG
AAACCACCAGTTTAATGAATTTTTATGGACAAGAAGAAAAATACCATACGATAACTGTAAGGGTTCATATCAAAAATTAT
CCTGCAGTTGCCTATATGATGGCAGTAGTAAATGTGGAACAATTAGACCGCGCTAATGAACGTTACGAGCGCATTATTAT
TATAGTTATGAGTGTTTTTTGGCTAATTTCTATTTTAGCAAGTATTTATTTAGCCAAGTGGAGCAGAAAACCTATTTTAG
AAAGCTATGAAAAACAAAAAATGTTTGTTGAAAATGCTAGTCATGAATTAAGGACCCCTTTGGCGGTCTTACAGAATCGT
CTGGAATCACTTTTTCGTAAGCCCAACGAAACGATATTAGAAAATAGTGAGCATCTCGCTTCTAGTTTAGACGAGGTTCG
CAACATGCGCATCTTAACAACTAATTTATTAAATTTAGCAAGACGAGATGATGGCATTAATCCACAGTGGACTCATTTAG
ATACAGATTTTTTTAATGCTATTTTTGAGAATTATGAACTAGTTGCTAAAGAATATGGAAAAATATTTTATTTTCAGAGC
CAAGTCAATAGATCGTTAAGAATGGATAAGGCTTTACTAAAACAATTAATAACGATTTTATTTGACAATGCTATTAAATA
TACAGATAAAAATGGTATTATTGAAATTATAGTGAAAACAACGGACAAAAATTTATTAATTTCTGTTATTGATAATGGTC
CAGGGATAACAGATGAAGAAAAGAAAAAGATTTTTGATCGTTTTTATCGAGTTGACAAAGCTAGAACACGGCAAACAGGT
GGATTTGGCTTGGGGTTGGCTTTAGCTCAGCAAATCGTGATGTCTTTAAAAGGAAATATTACAGTAAAGGATAATGATCC
TAAAGGTAGTATTTTTGAAGTCAAATTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (329-436)

• His Kinase A (phospho-acceptor) domain (HisKA) (220-285)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus mutans UA159	57.666	100	0.578
ciaH	Streptococcus pneumoniae Rx1	51.142	100	0.514
ciaH	Streptococcus pneumoniae D39	51.142	100	0.514
ciaH	Streptococcus pneumoniae R6	51.142	100	0.514
ciaH	Streptococcus pneumoniae TIGR4	51.142	100	0.514