Detailed information NTG0477214

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: H7792_RS06645
• Genome accession: NZ_CP060643
• Coordinates: 1360398..1361399 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain TSPY416
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1355398..1366399

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7792_RS06630 (H7792_06620)	thrS	1355568..1357511 (-)	1944	WP_030127185.1	threonine--tRNA ligase	-
H7792_RS06635 (H7792_06625)	-	1357933..1359267 (-)	1335	WP_030127184.1	glycosyltransferase family 4 protein	-
H7792_RS06640 (H7792_06630)	-	1359269..1360267 (-)	999	WP_030127183.1	glycosyltransferase family 4 protein	-
H7792_RS06645 (H7792_06635)	ccpA	1360398..1361399 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
H7792_RS06650 (H7792_06640)	-	1361573..1362658 (+)	1086	WP_030127182.1	aminopeptidase P family protein	-
H7792_RS06655 (H7792_06645)	-	1362707..1363372 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
H7792_RS06660 (H7792_06650)	-	1363383..1363760 (+)	378	WP_002985686.1	VOC family protein	-
H7792_RS06665 (H7792_06655)	-	1363905..1364831 (+)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
H7792_RS06670 (H7792_06660)	-	1365042..1365725 (+)	684	WP_012560521.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=477214 H7792_RS06645 WP_002985680.1 1360398..1361399(-) (ccpA) [Streptococcus pyogenes strain TSPY416]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=477214 H7792_RS06645 WP_002985680.1 1360398..1361399(-) (ccpA) [Streptococcus pyogenes strain TSPY416]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAATGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCTAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559