Detailed information NTG0477152

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: H7793_RS04640
• Genome accession: NZ_CP060642
• Coordinates: 899788..901098 (+)
• Length: 436 a.a.
• NCBI ID: WP_002989693.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY1312
• Function: Required for optimal comC expression (predicted from homology) Competence regulation

Genomic Context

Location: 894788..906098

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7793_RS04625 (H7793_04625)	phoU	895380..896033 (+)	654	WP_002984514.1	phosphate signaling complex protein PhoU	-
H7793_RS04630 (H7793_04630)	-	896238..898775 (+)	2538	WP_002989692.1	M1 family metallopeptidase	-
H7793_RS04635 (H7793_04635)	ciaR	899121..899795 (+)	675	WP_002984519.1	response regulator transcription factor	Regulator
H7793_RS04640 (H7793_04640)	ciaH	899788..901098 (+)	1311	WP_002989693.1	sensor histidine kinase	Regulator
H7793_RS04645 (H7793_04645)	rpsT	901223..901471 (-)	249	WP_009881183.1	30S ribosomal protein S20	-
H7793_RS04650 (H7793_04650)	coaA	901525..902445 (-)	921	WP_002989697.1	type I pantothenate kinase	-
H7793_RS04655 (H7793_04655)	-	902713..903305 (+)	593	Protein_866	class I SAM-dependent methyltransferase	-
H7793_RS04660 (H7793_04660)	-	903956..904345 (+)	390	WP_002984531.1	cytidine deaminase	-
H7793_RS04665 (H7793_04665)	-	904439..905491 (+)	1053	WP_002989701.1	BMP family protein	-

Sequence

Protein

• Length: 436 a.a.
• Molecular weight: 50119.65 Da
• Isoelectric Point: 9.0641

>NTDB_id=477152 H7793_RS04640 WP_002989693.1 899788..901098(+) (ciaH) [Streptococcus pyogenes strain TSPY1312]
MNKLKKEILSDNYNHFFHFFAVFTGIFVIMTIIILQIMRFGVYSSVDSSLVSVSNNASSYANRTMARISSFYFDTENNII
KALPDSDSSKLLGTPAANTDIILFSANGTILNAFDAFSNYQNFHLDKYRLGSIETTSLMNFYGQEEKYHTITVRVHIKNY
PAVAYMMAVVNVEQLDRANERYERIIIIVMSVFWLISILASIYLAKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTHLDTDFFNAIFENYELVAKEYGKIFYFQN
QVNRSLRMDKALLKQLITILFDNAIKYTDKNGIIEIIVKTTDKNLLISVIDNGPGITDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVMSLKGNITVKDNDPKGSIFEVKL

Nucleotide

• Length: 1311 bp

>NTDB_id=477152 H7793_RS04640 WP_002989693.1 899788..901098(+) (ciaH) [Streptococcus pyogenes strain TSPY1312]
ATGAATAAATTAAAAAAAGAGATTTTATCAGATAACTATAACCACTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTCATTATGACTATTATTATCTTACAGATTATGCGGTTTGGCGTTTATTCGTCAGTTGACAGTAGTTTAGTTTCTGTTA
GTAATAATGCAAGTAGCTATGCTAATCGTACGATGGCTAGAATATCTTCTTTTTACTTTGATACTGAAAATAACATTATT
AAGGCGCTGCCTGATTCAGATAGTTCTAAGTTATTAGGAACGCCTGCAGCTAATACAGATATCATTTTGTTTAGTGCTAA
TGGAACAATTTTAAATGCTTTTGATGCGTTTTCTAACTATCAAAATTTTCATTTAGATAAATACCGTTTGGGGAGTATTG
AAACCACCAGTTTAATGAATTTTTATGGACAAGAAGAAAAATACCATACGATAACTGTAAGGGTTCATATCAAAAATTAT
CCTGCAGTTGCCTATATGATGGCAGTAGTAAATGTGGAACAATTAGACCGCGCTAATGAACGTTACGAGCGCATTATTAT
TATAGTTATGAGTGTTTTTTGGCTAATTTCTATTTTAGCAAGTATTTATTTAGCCAAGTGGAGCAGAAAACCTATTTTAG
AAAGCTATGAAAAACAAAAAATGTTTGTTGAAAATGCTAGTCATGAACTAAGGACCCCTTTGGCGGTCTTACAGAATCGT
CTGGAATCGCTTTTTCGTAAGCCCAACGAAACGATATTAGAAAATAGTGAGCATCTCGCTTCTAGTTTAGACGAGGTTCG
CAACATGCGCATCTTAACAACTAATTTATTAAATTTAGCAAGACGAGATGATGGCATTAATCCACAGTGGACTCATTTAG
ATACAGATTTTTTTAATGCTATTTTTGAGAATTATGAACTAGTTGCTAAAGAATATGGAAAAATATTTTATTTTCAGAAC
CAAGTCAATAGATCGTTAAGAATGGATAAGGCTTTACTAAAACAATTAATAACGATTTTATTTGACAATGCTATTAAATA
TACAGATAAAAATGGTATTATTGAAATTATAGTGAAAACAACGGACAAAAATTTATTAATTTCTGTTATTGATAATGGTC
CAGGGATAACAGATGAAGAAAAGAAAAAGATTTTTGATCGTTTTTATCGAGTTGACAAAGCTAGAACACGGCAAACAGGT
GGATTTGGCTTGGGGTTGGCTTTAGCTCAGCAAATCGTGATGTCTTTAAAAGGAAATATTACAGTAAAGGATAATGATCC
TAAAGGTAGTATTTTTGAAGTCAAATTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (329-436)

• His Kinase A (phospho-acceptor) domain (HisKA) (220-285)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus mutans UA159	57.895	100	0.58
ciaH	Streptococcus pneumoniae Rx1	51.37	100	0.516
ciaH	Streptococcus pneumoniae D39	51.37	100	0.516
ciaH	Streptococcus pneumoniae R6	51.37	100	0.516
ciaH	Streptococcus pneumoniae TIGR4	51.37	100	0.516