Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYF   Type   Machinery gene
Locus tag   H7793_RS00680 Genome accession   NZ_CP060642
Coordinates   104486..104920 (+) Length   144 a.a.
NCBI ID   WP_002987783.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY1312     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 99486..109920
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7793_RS00650 (H7793_00655) - 101155..101520 (+) 366 WP_002986560.1 DUF1033 family protein -
  H7793_RS00655 (H7793_00660) comYA 101613..102551 (+) 939 WP_002987773.1 competence type IV pilus ATPase ComGA Machinery gene
  H7793_RS00660 (H7793_00665) comYB 102487..103521 (+) 1035 WP_223845212.1 competence type IV pilus assembly protein ComGB Machinery gene
  H7793_RS00665 (H7793_00670) comYC 103523..103849 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  H7793_RS00670 (H7793_00675) comGD 103824..104252 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  H7793_RS00675 (H7793_00680) comGE 104209..104493 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  H7793_RS00680 (H7793_00685) comYF 104486..104920 (+) 435 WP_002987783.1 competence type IV pilus minor pilin ComGF Machinery gene
  H7793_RS00685 (H7793_00690) comGG 104904..105230 (+) 327 WP_002987787.1 competence type IV pilus minor pilin ComGG -
  H7793_RS00690 (H7793_00695) comYH 105328..106281 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  H7793_RS00695 (H7793_00700) - 106340..107536 (+) 1197 WP_002987791.1 acetate kinase -
  H7793_RS00700 (H7793_00705) - 107723..108031 (+) 309 WP_011284425.1 hypothetical protein -
  H7793_RS00705 (H7793_00710) proC 108114..108884 (-) 771 WP_002986527.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 144 a.a.        Molecular weight: 16585.23 Da        Isoelectric Point: 10.2064

>NTDB_id=477126 H7793_RS00680 WP_002987783.1 104486..104920(+) (comYF) [Streptococcus pyogenes strain TSPY1312]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFCKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide


Download         Length: 435 bp        

>NTDB_id=477126 H7793_RS00680 WP_002987783.1 104486..104920(+) (comYF) [Streptococcus pyogenes strain TSPY1312]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTCCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTACCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTGCAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGATATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(41-135)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYF Streptococcus mutans UA140

51.079

96.528

0.493
  comYF Streptococcus mutans UA159

50.36

96.528

0.486
  comGF Lactococcus lactis subsp. cremoris KW2

46.715

95.139

0.444
  comGF/cglF Streptococcus mitis NCTC 12261

44.776

93.056

0.417
  comGF/cglF Streptococcus pneumoniae Rx1

43.609

92.361

0.403
  comGF/cglF Streptococcus pneumoniae D39

43.609

92.361

0.403
  comGF/cglF Streptococcus pneumoniae R6

43.609

92.361

0.403
  comGF/cglF Streptococcus pneumoniae TIGR4

43.609

92.361

0.403
  comGF/cglF Streptococcus mitis SK321

42.857

92.361

0.396