Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYF   Type   Machinery gene
Locus tag   H7796_RS00665 Genome accession   NZ_CP060640
Coordinates   104921..105355 (+) Length   144 a.a.
NCBI ID   WP_002986542.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY764     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 99921..110355
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7796_RS00635 (H7796_00645) - 101590..101955 (+) 366 WP_002986560.1 DUF1033 family protein -
  H7796_RS00640 (H7796_00650) comYA 102048..102986 (+) 939 WP_002986557.1 competence type IV pilus ATPase ComGA Machinery gene
  H7796_RS00645 (H7796_00655) comYB 102922..103956 (+) 1035 WP_228631569.1 competence type IV pilus assembly protein ComGB Machinery gene
  H7796_RS00650 (H7796_00660) comYC 103958..104284 (+) 327 WP_011528161.1 competence type IV pilus major pilin ComGC Machinery gene
  H7796_RS00655 (H7796_00665) comGD 104259..104687 (+) 429 WP_076639399.1 competence type IV pilus minor pilin ComGD -
  H7796_RS00660 (H7796_00670) comGE 104644..104928 (+) 285 WP_307777288.1 competence type IV pilus minor pilin ComGE -
  H7796_RS00665 (H7796_00675) comYF 104921..105355 (+) 435 WP_002986542.1 competence type IV pilus minor pilin ComGF Machinery gene
  H7796_RS00670 (H7796_00680) comGG 105339..105665 (+) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  H7796_RS00675 (H7796_00685) comYH 105763..106716 (+) 954 WP_010921802.1 class I SAM-dependent methyltransferase Machinery gene
  H7796_RS00680 (H7796_00690) - 106775..107971 (+) 1197 WP_020904834.1 acetate kinase -
  H7796_RS00685 (H7796_00695) - 108158..108466 (+) 309 Protein_89 hypothetical protein -
  H7796_RS00690 (H7796_00700) proC 108549..109319 (-) 771 WP_076639397.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 144 a.a.        Molecular weight: 16573.20 Da        Isoelectric Point: 10.3584

>NTDB_id=477021 H7796_RS00665 WP_002986542.1 104921..105355(+) (comYF) [Streptococcus pyogenes strain TSPY764]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIGQSQICITLKWKSGLERTFYYAFQD

Nucleotide


Download         Length: 435 bp        

>NTDB_id=477021 H7796_RS00665 WP_002986542.1 104921..105355(+) (comYF) [Streptococcus pyogenes strain TSPY764]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTATCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAG
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTCCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGCTATTTGGAATATCACGTAGTCATATTCACATAGGGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(41-135)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYF Streptococcus mutans UA140

51.079

96.528

0.493
  comYF Streptococcus mutans UA159

50.36

96.528

0.486
  comGF Lactococcus lactis subsp. cremoris KW2

45.985

95.139

0.437
  comGF/cglF Streptococcus mitis NCTC 12261

44.03

93.056

0.41
  comGF/cglF Streptococcus pneumoniae Rx1

43.609

92.361

0.403
  comGF/cglF Streptococcus pneumoniae D39

43.609

92.361

0.403
  comGF/cglF Streptococcus pneumoniae R6

43.609

92.361

0.403
  comGF/cglF Streptococcus pneumoniae TIGR4

43.609

92.361

0.403
  comGF/cglF Streptococcus mitis SK321

42.857

92.361

0.396